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Related papers: QUBIQ: Uncertainty Quantification for Biomedical I…

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Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

Accurate medical image segmentation is crucial for diagnosis and analysis. However, the models without calibrated uncertainty estimates might lead to errors in downstream analysis and exhibit low levels of robustness. Estimating the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Yanwu Yang , Xutao Guo , Yiwei Pan , Pengcheng Shi , Haiyan Lv , Ting Ma

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

Deep learning (DL) models have provided state-of-the-art performance in various medical imaging benchmarking challenges, including the Brain Tumor Segmentation (BraTS) challenges. However, the task of focal pathology multi-compartment…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Raghav Mehta , Angelos Filos , Ujjwal Baid , Chiharu Sako , Richard McKinley , Michael Rebsamen , Katrin Datwyler , Raphael Meier , Piotr Radojewski , Gowtham Krishnan Murugesan , Sahil Nalawade , Chandan Ganesh , Ben Wagner , Fang F. Yu , Baowei Fei , Ananth J. Madhuranthakam , Joseph A. Maldjian , Laura Daza , Catalina Gomez , Pablo Arbelaez , Chengliang Dai , Shuo Wang , Hadrien Reynaud , Yuan-han Mo , Elsa Angelini , Yike Guo , Wenjia Bai , Subhashis Banerjee , Lin-min Pei , Murat AK , Sarahi Rosas-Gonzalez , Ilyess Zemmoura , Clovis Tauber , Minh H. Vu , Tufve Nyholm , Tommy Lofstedt , Laura Mora Ballestar , Veronica Vilaplana , Hugh McHugh , Gonzalo Maso Talou , Alan Wang , Jay Patel , Ken Chang , Katharina Hoebel , Mishka Gidwani , Nishanth Arun , Sharut Gupta , Mehak Aggarwal , Praveer Singh , Elizabeth R. Gerstner , Jayashree Kalpathy-Cramer , Nicolas Boutry , Alexis Huard , Lasitha Vidyaratne , Md Monibor Rahman , Khan M. Iftekharuddin , Joseph Chazalon , Elodie Puybareau , Guillaume Tochon , Jun Ma , Mariano Cabezas , Xavier Llado , Arnau Oliver , Liliana Valencia , Sergi Valverde , Mehdi Amian , Mohammadreza Soltaninejad , Andriy Myronenko , Ali Hatamizadeh , Xue Feng , Quan Dou , Nicholas Tustison , Craig Meyer , Nisarg A. Shah , Sanjay Talbar , Marc-Andre Weber , Abhishek Mahajan , Andras Jakab , Roland Wiest , Hassan M. Fathallah-Shaykh , Arash Nazeri , Mikhail Milchenko1 , Daniel Marcus , Aikaterini Kotrotsou , Rivka Colen , John Freymann , Justin Kirby , Christos Davatzikos , Bjoern Menze , Spyridon Bakas , Yarin Gal , Tal Arbel

Although segmenting natural images has shown impressive performance, these techniques cannot be directly applied to medical image segmentation. Medical image segmentation is particularly complicated by inherent uncertainties. For instance,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-06 Jiayuan Zhu , Junde Wu

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

Despite the recent improvements in overall accuracy, deep learning systems still exhibit low levels of robustness. Detecting possible failures is critical for a successful clinical integration of these systems, where each data point…

Image and Video Processing · Electrical Eng. & Systems 2019-10-14 Alain Jungo , Mauricio Reyes

The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor

The comprehensive integration of machine learning healthcare models within clinical practice remains suboptimal, notwithstanding the proliferation of high-performing solutions reported in the literature. A predominant factor hindering…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Ling Huang , Su Ruan , Yucheng Xing , Mengling Feng

Reliable uncertainty quantification is crucial for trustworthy decision-making and the deployment of AI models in medical imaging. While prior work has explored the ability of neural networks to quantify predictive, epistemic, and aleatoric…

Machine Learning · Statistics 2025-08-07 Simon Baur , Wojciech Samek , Jackie Ma

This paper explores uncertainty quantification (UQ) as an indicator of the trustworthiness of automated deep-learning (DL) tools in the context of white matter lesion (WML) segmentation from magnetic resonance imaging (MRI) scans of…

Deep learning based methods for automatic organ segmentation have shown promise in aiding diagnosis and treatment planning. However, quantifying and understanding the uncertainty associated with model predictions is crucial in critical…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Jadie Adams , Shireen Y. Elhabian

Uncertainty Quantification (UQ) is pivotal in enhancing the robustness, reliability, and interpretability of Machine Learning (ML) systems for healthcare, optimizing resources and improving patient care. Despite the emergence of ML-based…

Machine Learning · Computer Science 2025-05-07 L. Julián Lechuga López , Shaza Elsharief , Dhiyaa Al Jorf , Firas Darwish , Congbo Ma , Farah E. Shamout

Uncertainty estimation is important for interpreting the trustworthiness of machine learning models in many applications. This is especially critical in the data-driven active learning setting where the goal is to achieve a certain accuracy…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Bo Li , Tommy Sonne Alstrøm

Recent advances in deep learning have led to its widespread adoption across diverse domains, including medical imaging. This progress is driven by increasingly sophisticated model architectures, such as ResNets, Vision Transformers, and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Akshat Dubey , Aleksandar Anžel , Bahar İlgen , Georges Hattab

Advances in architectural design, data availability, and compute have driven remarkable progress in semantic segmentation. Yet, these models often rely on relaxed Bayesian assumptions, omitting critical uncertainty information needed for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 M. M. A. Valiuddin , R. J. G. van Sloun , C. G. A. Viviers , P. H. N. de With , F. van der Sommen

Uncertainty quantification (UQ) has become critical for evaluating the reliability of artificial intelligence systems, especially in medical image segmentation. This study addresses the interpretability of instance-wise uncertainty values…

Learning a medical image segmentation model is an inherently ambiguous task, as uncertainties exist in both images (noise) and manual annotations (human errors and bias) used for model training. To build a trustworthy image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Xinyu Bai , Wenjia Bai

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu
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