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Augmentation is an effective alternative to utilize the small amount of labeled protein data. However, most of the existing work focuses on design-ing new architectures or pre-training tasks, and relatively little work has studied data…

Quantitative Methods · Quantitative Biology 2024-03-05 Rui Sun , Lirong Wu , Haitao Lin , Yufei Huang , Stan Z. Li

Protein fitness optimization is challenged by a vast combinatorial landscape where high-fitness variants are extremely sparse. Many current methods either underperform or require computationally expensive gradient-based sampling. We present…

Specialist language models (LMs) focus on a specific task or domain on which they often outperform generalist LMs of the same size. However, the specialist data needed to pretrain these models is only available in limited amount for most…

Computation and Language · Computer Science 2025-03-12 David Grangier , Simin Fan , Skyler Seto , Pierre Ablin

We present a new approach to encourage neural machine translation to satisfy lexical constraints. Our method acts at the training step and thereby avoiding the introduction of any extra computational overhead at inference step. The proposed…

Computation and Language · Computer Science 2021-06-08 Melissa Ailem , Jinghsu Liu , Raheel Qader

Model pruning technique is vital for accelerating large language models by reducing their size and computational requirements. However, the generalizability of existing pruning methods across diverse datasets and tasks remains unclear.…

Computation and Language · Computer Science 2025-03-04 Yizhuo Ding , Xinwei Sun , Yanwei Fu , Guosheng Hu

While experience replay is essential for data efficiency in reinforcement learning (RL), standard methods treat the replay buffer as a passive memory system, prioritizing samples based on numerical prediction errors rather than their…

Artificial Intelligence · Computer Science 2026-05-12 Yanan Xiao , Yixiang Tang , Zechen Feng , Lu Jiang , Minghao Yin , Pengyang Wang

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

Artificial Intelligence · Computer Science 2024-12-06 Yoav Kan-Tor , Michael Morris Danziger , Eden Zohar , Matan Ninio , Yishai Shimoni

The rapid advancement of large language models (LLMs) has led to significant improvements in natural language processing but also poses challenges due to their high computational and energy demands. This paper introduces a series of…

Computation and Language · Computer Science 2024-06-27 Dylan Hillier , Leon Guertler , Cheston Tan , Palaash Agrawal , Chen Ruirui , Bobby Cheng

This study proposes a text classification algorithm based on large language models, aiming to address the limitations of traditional methods in capturing long-range dependencies, understanding contextual semantics, and handling class…

Computation and Language · Computer Science 2025-12-11 Ning Lyu , Yuxi Wang , Feng Chen , Qingyuan Zhang

We propose a novel approach for using unsupervised boosting to create an ensemble of generative models, where models are trained in sequence to correct earlier mistakes. Our meta-algorithmic framework can leverage any existing base learner…

Machine Learning · Computer Science 2017-12-25 Aditya Grover , Stefano Ermon

Continued pre-training of small language models offers a promising path for domain adaptation with limited computational resources. I've investigated this approach within educational domains, evaluating it as a resource-efficient…

Computation and Language · Computer Science 2025-04-15 Salman Faroz

Recent breakthroughs and successful deployment of large language and vision models in a constrained environment predominantly follow a two phase approach. First, large models are trained to achieve peak performance, followed by a model…

Machine Learning · Computer Science 2024-11-22 Hanna Mazzawi , Pranjal Awasthi , Xavi Gonzalvo , Srikumar Ramalingam

Retrieval augmentation has become an effective solution to empower large language models (LLMs) with external and verified knowledge sources from the database, which overcomes the limitations and hallucinations of LLMs in handling…

Information Retrieval · Computer Science 2023-11-21 Tong Wu , Yulei Qin , Enwei Zhang , Zihan Xu , Yuting Gao , Ke Li , Xing Sun

Gradient boosting from the field of statistical learning is widely known as a powerful framework for estimation and selection of predictor effects in various regression models by adapting concepts from classification theory. Current…

Methodology · Statistics 2020-11-03 Colin Griesbach , Benjamin Säfken , Elisabeth Waldmann

There have been many recent investigations into prompt-based training of transformer language models for new text genres in low-resource settings. The prompt-based training approach has been found to be effective in generalizing pre-trained…

Computation and Language · Computer Science 2023-06-13 Jennifer D'Souza , Moussab Hrou , Sören Auer

We classify and re-examine some of the current approaches to improve the performance-computes trade-off of language models, including (1) non-causal models (such as masked language models), (2) extension of batch length with efficient…

Computation and Language · Computer Science 2020-09-16 Aran Komatsuzaki

Through prompting, large-scale pre-trained models have become more expressive and powerful, gaining significant attention in recent years. Though these big models have zero-shot capabilities, in general, labeled data are still required to…

Machine Learning · Computer Science 2023-05-02 Korawat Tanwisuth , Shujian Zhang , Huangjie Zheng , Pengcheng He , Mingyuan Zhou

Model-based methods and deep neural networks have both been tremendously successful paradigms in machine learning. In model-based methods, problem domain knowledge can be built into the constraints of the model, typically at the expense of…

Machine Learning · Computer Science 2014-11-21 John R. Hershey , Jonathan Le Roux , Felix Weninger

We present a framework for optimizing prompts in vision-language models to elicit multimodal reasoning without model retraining. Using an evolutionary algorithm to guide prompt updates downstream of visual tasks, our approach improves upon…

Computation and Language · Computer Science 2025-04-01 Sid Bharthulwar , John Rho , Katrina Brown

We propose Neural Priming, a technique for adapting large pretrained models to distribution shifts and downstream tasks given few or no labeled examples. Presented with class names or unlabeled test samples, Neural Priming enables the model…