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Accurate and robust medical image classification is paramount for early disease diagnosis and treatment planning. However, challenges such as limited annotated data, high intra-class variability, and subtle inter-class differences often…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Joao Florindo , Viviane Moura

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Recent advances in Spatial Transcriptomics (ST) pair histology images with spatially resolved gene expression profiles, enabling predictions of gene expression across different tissue locations based on image patches. This opens up new…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Aniruddha Ganguly , Debolina Chatterjee , Wentao Huang , Jie Zhang , Alisa Yurovsky , Travis Steele Johnson , Chao Chen

Deep learning techniques have emerged as a promising approach to highly accelerated MRI. However, recent reconstruction challenges have shown several drawbacks in current deep learning approaches, including the loss of fine image details…

Computer Vision and Pattern Recognition · Computer Science 2021-09-24 Ruiyang Zhao , Yuxin Zhang , Burhaneddin Yaman , Matthew P. Lungren , Michael S. Hansen

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

A Whole Slide Image (WSI) is a high-resolution digital image created by scanning an entire glass slide containing a biological specimen, such as tissue sections or cell samples, at multiple magnifications. These images are digitally…

Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

Recently, the Network Representation Learning (NRL) techniques, which represent graph structure via low-dimension vectors to support social-oriented application, have attracted wide attention. Though large efforts have been made, they may…

Social and Information Networks · Computer Science 2019-05-28 Hao Wang , Tong Xu , Qi Liu , Defu Lian , Enhong Chen , Dongfang Du , Han Wu , Wen Su

Graph-based methods have been extensively applied to whole-slide histopathology image (WSI) analysis due to the advantage of modeling the spatial relationships among different entities. However, most of the existing methods focus on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Tsai Hor Chan , Fernando Julio Cendra , Lan Ma , Guosheng Yin , Lequan Yu

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). However, existing approaches typically rely on pre-trained models from large natural image datasets, such as…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Yi Lin , Zhongchen Zhao , Zhengjie ZHU , Lisheng Wang , Kwang-Ting Cheng , Hao Chen

Survival prediction is a complex ordinal regression task that aims to predict the survival coefficient ranking among a cohort of patients, typically achieved by analyzing patients' whole slide images. Existing deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Minghao Han , Xukun Zhang , Dingkang Yang , Tao Liu , Haopeng Kuang , Jinghui Feng , Lihua Zhang

Existing Multimodal Large Language Models (MLLMs) struggle with 3D spatial reasoning, as they fail to construct structured abstractions of the 3D environment depicted in video inputs. To bridge this gap, drawing inspiration from cognitive…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Jiacheng Hua , Yishu Yin , Yuhang Wu , Tai Wang , Yifei Huang , Miao Liu

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Text-to-image retrieval (TIR) aims to find relevant images based on a textual query, but existing approaches are primarily based on whole-image captions and lack interpretability. Meanwhile, referring expression segmentation (RES) enables…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Li-Cheng Shen , Jih-Kang Hsieh , Wei-Hua Li , Chu-Song Chen

Until recently, the number of public real-world text images was insufficient for training scene text recognizers. Therefore, most modern training methods rely on synthetic data and operate in a fully supervised manner. Nevertheless, the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Aviad Aberdam , Roy Ganz , Shai Mazor , Ron Litman

Accurate travel time estimation (TTE) plays a crucial role in intelligent transportation systems. However, it remains challenging due to heterogeneous data sources and complex traffic dynamics. Moreover, traditional approaches typically…

Machine Learning · Computer Science 2026-01-27 Zhi Liu , Xuyuan Hu , Xiao Han , Zhehao Dai , Zhaolin Deng , Guojiang Shen , Xiangjie Kong

Multi-modal reasoning systems rely on a pre-trained object detector to extract regions of interest from the image. However, this crucial module is typically used as a black box, trained independently of the downstream task and on a fixed…

Computer Vision and Pattern Recognition · Computer Science 2021-10-13 Aishwarya Kamath , Mannat Singh , Yann LeCun , Gabriel Synnaeve , Ishan Misra , Nicolas Carion

In digital pathology, Whole Slide Image (WSI) analysis is usually formulated as a Multiple Instance Learning (MIL) problem. Although transformer-based architectures have been used for WSI classification, these methods require modifications…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Juan I. Pisula , Katarzyna Bozek

Learning good representation of giga-pixel level whole slide pathology images (WSI) for downstream tasks is critical. Previous studies employ multiple instance learning (MIL) to represent WSIs as bags of sampled patches because, for most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Chunyuan Li , Xinliang Zhu , Jiawen Yao , Junzhou Huang