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Extracting actionable insight from Electronic Health Records (EHRs) poses several challenges for traditional machine learning approaches. Patients are often missing data relative to each other; the data comes in a variety of modalities,…

Machine Learning · Computer Science 2018-11-13 Brandon Malone , Alberto Garcia-Duran , Mathias Niepert

Time-series analysis is often affected by missing data, a common problem across several fields, including healthcare and environmental monitoring. Multiple Imputation by Chained Equations (MICE) has been prominent for imputing missing…

Machine Learning · Statistics 2026-04-10 Amuche Ibenegbu , Pierre Lafaye de Micheaux , Rohitash Chandra

Missingness is a common issue for neuroimaging data, and neglecting it in downstream statistical analysis can introduce bias and lead to misguided inferential conclusions. It is therefore crucial to conduct appropriate statistical methods…

Methodology · Statistics 2025-03-25 Tong Lu , Chixiang Chen , Hsin-Hsiung Huang , Peter Kochunov , Elliot Hong , Shuo Chen

Estimating the causal effect of time-varying treatments on survival outcomes is a challenging task in many domains, particularly in medicine where treatment protocols adapt over time. While recent advances in representation learning have…

Machine Learning · Statistics 2025-05-06 Ayoub Abraich

Healthcare clinics regularly encounter dynamic data that changes due to variations in patient populations, treatment policies, medical devices, and emerging disease patterns. Deep learning models can suffer from catastrophic forgetting when…

Machine Learning · Computer Science 2023-11-09 Amritpal Singh , Mustafa Burak Gurbuz , Shiva Souhith Gantha , Prahlad Jasti

Inferring causal effects of treatments is a central goal in many disciplines. The potential outcomes framework is a main statistical approach to causal inference, in which a causal effect is defined as a comparison of the potential outcomes…

Methodology · Statistics 2018-01-04 Peng Ding , Fan Li

Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…

The imputation of missing values in time series has many applications in healthcare and finance. While autoregressive models are natural candidates for time series imputation, score-based diffusion models have recently outperformed existing…

Machine Learning · Computer Science 2021-10-28 Yusuke Tashiro , Jiaming Song , Yang Song , Stefano Ermon

Time series imputation models have traditionally been developed using complete datasets with artificial masking patterns to simulate missing values. However, in real-world infrastructure monitoring, practitioners often encounter datasets…

Machine Learning · Computer Science 2025-06-26 Ryan Hildebrant , Rahul Bhope , Sharad Mehrotra , Christopher Tull , Nalini Venkatasubramanian

Time roots in applying language models for biomedical applications: models are trained on historical data and will be deployed for new or future data, which may vary from training data. While increasing biomedical tasks have employed…

Computation and Language · Computer Science 2024-08-13 Weisi Liu , Zhe He , Xiaolei Huang

Multiple imputation (MI) is a popular approach for dealing with missing data arising from non-response in sample surveys. Multiple imputation by chained equations (MICE) is one of the most widely used MI algorithms for multivariate data,…

Machine Learning · Computer Science 2022-03-22 Zhenhua Wang , Olanrewaju Akande , Jason Poulos , Fan Li

An increasing number of large-scale multi-modal research initiatives has been conducted in the typically developing population, as well as in psychiatric cohorts. Missing data is a common problem in such datasets due to the difficulty of…

Patient time series classification faces challenges in high degrees of dimensionality and missingness. In light of patient similarity theory, this study explores effective temporal feature engineering and reduction, missing value…

Artificial Intelligence · Computer Science 2017-05-02 Mohammad Amin Morid , Olivia R. Liu Sheng , Samir Abdelrahman

The masking-one-out (MOO) procedure, masking an observed entry and comparing it versus its imputed values, is a very common procedure for comparing imputation models. We study the optimum of this procedure and generalize it to a missing…

Methodology · Statistics 2025-11-14 Yanjiao Yang , Daniel Suen , Yen-Chi Chen

Clinical time series data are critical for patient monitoring and predictive modeling. These time series are typically multivariate and often comprise hundreds of heterogeneous features from different data sources. The grouping of features…

Machine Learning · Computer Science 2025-11-12 Fedor Sergeev , Manuel Burger , Polina Leshetkina , Vincent Fortuin , Gunnar Rätsch , Rita Kuznetsova

Data mining and machine learning hold great potential to enable health systems to systematically use data and analytics to identify inefficiencies and best practices that improve care and reduce costs. Waveform data offers particularly…

Machine Learning · Computer Science 2025-03-17 Michael Albada

Time series forecasting using historical data has been an interesting and challenging topic, especially when the data is corrupted by missing values. In many industrial problem, it is important to learn the inference function between the…

Machine Learning · Computer Science 2023-06-02 Trang H. Tran , Lam M. Nguyen , Kyongmin Yeo , Nam Nguyen , Dzung Phan , Roman Vaculin , Jayant Kalagnanam

Shared mental models are critical to team success; however, in practice, team members may have misaligned models due to a variety of factors. In safety-critical domains (e.g., aviation, healthcare), lack of shared mental models can lead to…

Artificial Intelligence · Computer Science 2022-05-11 Sangwon Seo , Lauren R. Kennedy-Metz , Marco A. Zenati , Julie A. Shah , Roger D. Dias , Vaibhav V. Unhelkar

Missing data can significantly hamper standard time series analysis, yet they occur frequently in applications. In this paper, we introduce temporal Wasserstein imputation, a novel method for imputing missing data in time series. Unlike…

Methodology · Statistics 2025-08-15 Shuo-Chieh Huang , Tengyuan Liang , Ruey S. Tsay

Predicting the risk of in-hospital mortality from electronic health records (EHRs) has received considerable attention. Such predictions will provide early warning of a patient's health condition to healthcare professionals so that timely…

Machine Learning · Computer Science 2023-08-22 Yuxi Liu , Zhenhao Zhang , Shaowen Qin , Flora D. Salim , Antonio Jimeno Yepes