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Deep learning models have achieved state-of-the-art performance in many classification tasks. However, most of them cannot provide an interpretation for their classification results. Machine learning models that are interpretable are…

Machine Learning · Computer Science 2021-11-04 Miles Q. Li , Benjamin C. M. Fung , Adel Abusitta

Deep neural networks (DNNs) achieve remarkable predictive performance but remain difficult to interpret, largely due to overparameterization that obscures the minimal structure required for interpretation. Here we introduce DeepIn, a…

Methodology · Statistics 2026-03-26 Zhiyao Tan , Liu Li , Huazhen Lin

State of the art machine learning algorithms are highly optimized to provide the optimal prediction possible, naturally resulting in complex models. While these models often outperform simpler more interpretable models by order of…

Machine Learning · Statistics 2016-11-24 Yotam Hechtlinger

Deep neural networks excel in mapping genomic DNA sequences to associated readouts (e.g., protein-DNA binding). Beyond prediction, the goal of these networks is to reveal to scientists the underlying motifs (and their syntax) which drive…

Genomics · Quantitative Biology 2024-10-10 Alex M. Tseng , Gokcen Eraslan , Tommaso Biancalani , Gabriele Scalia

Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user…

Machine Learning · Statistics 2016-06-20 Marco Tulio Ribeiro , Sameer Singh , Carlos Guestrin

Along with the great success of deep neural networks, there is also growing concern about their black-box nature. The interpretability issue affects people's trust on deep learning systems. It is also related to many ethical problems, e.g.,…

Machine Learning · Computer Science 2022-02-01 Yu Zhang , Peter Tiňo , Aleš Leonardis , Ke Tang

Mechanistic Interpretability aims to reverse engineer the algorithms implemented by neural networks by studying their weights and activations. An obstacle to reverse engineering neural networks is that many of the parameters inside a…

Deep learning has achieved remarkable success across many domains, but it has also created a growing demand for interpretability in model predictions. Although many explainable machine learning methods have been proposed, post-hoc…

Machine Learning · Computer Science 2026-01-28 Shijian Xu , Marcello Massimo Negri , Volker Roth

We formalize a novel modeling framework for achieving interpretability in deep learning, anchored in the principle of inference equivariance. While the direct verification of interpretability scales exponentially with the number of…

Finding human-understandable circuits in language models is a central goal of the field of mechanistic interpretability. We train models to have more understandable circuits by constraining most of their weights to be zeros, so that each…

Machine Learning · Computer Science 2025-11-18 Leo Gao , Achyuta Rajaram , Jacob Coxon , Soham V. Govande , Bowen Baker , Dan Mossing

To build intelligent machine learning systems, there are two broad approaches. One approach is to build inherently interpretable models, as endeavored by the growing field of causal representation learning. The other approach is to build…

Machine Learning · Computer Science 2024-12-10 Goutham Rajendran , Simon Buchholz , Bryon Aragam , Bernhard Schölkopf , Pradeep Ravikumar

Machine learning models that first learn a representation of a domain in terms of human-understandable concepts, then use it to make predictions, have been proposed to facilitate interpretation and interaction with models trained on…

Machine Learning · Computer Science 2020-12-08 Isaac Lage , Finale Doshi-Velez

Deep neural networks (DNNs) have demonstrated impressive performance on a wide array of tasks, but they are usually considered opaque since internal structure and learned parameters are not interpretable. In this paper, we re-examine the…

Computer Vision and Pattern Recognition · Computer Science 2017-08-21 Yinpeng Dong , Hang Su , Jun Zhu , Fan Bao

Despite the recent success of neural network models in mimicking animal performance on visual perceptual tasks, critics worry that these models fail to illuminate brain function. We take it that a central approach to explanation in systems…

Neurons and Cognition · Quantitative Biology 2021-04-13 Rosa Cao , Daniel Yamins

Machine Learning algorithms are increasingly being used in recent years due to their flexibility in model fitting and increased predictive performance. However, the complexity of the models makes them hard for the data analyst to interpret…

Machine Learning · Statistics 2018-06-07 Joel Vaughan , Agus Sudjianto , Erind Brahimi , Jie Chen , Vijayan N. Nair

We propose a new interpretability method for neural networks, which is based on a novel mathematico-philosophical theory of reasons. Our method computes a vector for each neuron, called its reasons vector. We then can compute how strongly…

Machine Learning · Computer Science 2025-05-21 Levin Hornischer , Hannes Leitgeb

The rapid evolution of machine learning (ML) has led to the widespread adoption of complex "black box" models, such as deep neural networks and ensemble methods. These models exhibit exceptional predictive performance, making them…

Machine Learning · Computer Science 2025-03-28 Moncef Garouani , Josiane Mothe , Ayah Barhrhouj , Julien Aligon

While the uptake of data-driven approaches for materials science and chemistry is at an exciting, early stage, to realise the true potential of machine learning models for successful scientific discovery, they must have qualities beyond…

Materials Science · Physics 2022-06-28 Felipe Oviedo , Juan Lavista Ferres , Tonio Buonassisi , Keith Butler

The interpretability of neural networks (NNs) is a challenging but essential topic for transparency in the decision-making process using machine learning. One of the reasons for the lack of interpretability is random weight initialization,…

Machine Learning · Computer Science 2021-03-01 Shohei Kubota , Hideaki Hayashi , Tomohiro Hayase , Seiichi Uchida

Explaining recommendations enables users to understand whether recommended items are relevant to their needs and has been shown to increase their trust in the system. More generally, if designing explainable machine learning models is key…

Machine Learning · Computer Science 2020-08-27 Darius Afchar , Romain Hennequin
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