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Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

Quantitative Methods · Quantitative Biology 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

Learning in structured, multi-context, or non-stationary environments involves two orthogonal difficulties. The first is \emph{metric}: once the correct context is known, how hard is prediction within it? This is the domain of Statistical…

Machine Learning · Computer Science 2026-05-08 Xin Li

Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…

Machine Learning · Statistics 2014-03-26 Takanori Watanabe , Daniel Kessler , Clayton Scott , Michael Angstadt , Chandra Sripada

Graph theoretical analyses have become standard tools in modeling functional and anatomical connectivity in the brain. With the advent of connectomics, the primary graphs or networks of interest are structural connectome (derived from DTI…

Neurons and Cognition · Quantitative Biology 2022-07-07 Carlo Amodeo , Igor Fortel , Olusola Ajilore , Liang Zhan , Alex Leow , Theja Tulabandhula

Brain networks can be defined and explored through their connectivity. Here, we analyzed the relationship between structural connectivity (SC) across 2,514 regions that cover the entire brain and brainstem, and their dynamic functional…

The brain's functional connectivity fluctuates over time instead of remaining steady in a stationary mode even during the resting state. This fluctuation establishes the dynamical functional connectivity that transitions in a non-random…

Neurons and Cognition · Quantitative Biology 2022-03-28 Shikuang Deng , Jingwei Li , B. T. Thomas Yeo , Shi Gu

Whole-brain computational modeling based on structural connectivity has shown great promise in successfully simulating fMRI BOLD signals with temporal co-activation patterns that are highly similar to empirical functional connectivity…

Neurons and Cognition · Quantitative Biology 2019-11-14 Neda Kaboodvand , Martijn P van den Heuvel , Peter Fransson

Networked systems display complex patterns of interactions between a large number of components. In physical networks, these interactions often occur along structural connections that link components in a hard-wired connection topology,…

Neurons and Cognition · Quantitative Biology 2018-04-03 Jason Kim , Jonathan M. Soffer , Ari E. Kahn , Jean M. Vettel , Fabio Pasqualetti , Danielle S. Bassett

In systems and network neuroscience, many common practices in brain connectomic analysis are often not properly scrutinized. One such practice is mapping a predetermined set of sub-circuits, like functional networks (FNs), onto subjects'…

Structural and functional heterogeneity are hallmarks of cortical circuits, from broad degree distributions in the mouse connectome to diverse intrinsic neuronal timescales. Yet a mechanistic link between connectivity heterogeneity and…

Neurons and Cognition · Quantitative Biology 2026-03-05 Marco Zenari , Luca Taffarello , Luca Mazzucato , Amos Maritan , Samir Suweis

Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…

Neurons and Cognition · Quantitative Biology 2016-04-29 Timothée Proix , Fabrice Bartolomei , Maxime Guye , Viktor K. Jirsa

The correlations of several fundamental properties of human brain connections are investigated in a consensus connectome, constructed from 1064 braingraphs, each on 1015 vertices, corresponding to 1015 anatomical brain areas. The properties…

Neurons and Cognition · Quantitative Biology 2024-04-22 Dániel Hegedűs , Vince Grolmusz

In this paper, we focus on how to locate the relevant or discriminative brain regions related with external stimulus or certain mental decease, which is also called support identification, based on the neuroimaging data. The main difficulty…

Computer Vision and Pattern Recognition · Computer Science 2015-06-09 Yilun Wang , Sheng Zhang , Junjie Zheng , Heng Chen , Huafu Chen

By varying the disorder realisation in the many-body localised (MBL) phase, we investigate the influence of resonances on spectral properties. The standard theory of the MBL phase is based on the existence of local integrals of motion…

Disordered Systems and Neural Networks · Physics 2021-11-29 S. J. Garratt , Sthitadhi Roy , J. T. Chalker

Cortical folding exhibits substantial inter-individual variability while preserving stable anatomical landmarks that enable fine-scale characterization of cortical organization. Among these, the three-hinge gyrus (3HG) serves as a key…

Neurons and Cognition · Quantitative Biology 2026-02-03 Minheng Chen , Tong Chen , Yan Zhuang , Chao Cao , Jing Zhang , Tianming Liu , Lu Zhang , Dajiang Zhu

Correlations in the signal observed via functional Magnetic Resonance Imaging (fMRI), are expected to reveal the interactions in the underlying neural populations through hemodynamic response. In particular, they highlight distributed set…

Applications · Statistics 2012-02-07 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

Machine Learning · Computer Science 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…

The estimation of sparse hierarchical components reflecting patterns of the brain's functional connectivity from rsfMRI data can contribute to our understanding of the brain's functional organization, and can lead to biomarkers of diseases.…

Machine Learning · Computer Science 2021-04-22 Dushyant Sahoo , Christos Davatzikos

It is widely believed that the formation of brain network structure is under the pressure of optimal trade-off between reducing wiring cost and promoting communication efficiency. However, the question of whether this trade-off exists in…

Neurons and Cognition · Quantitative Biology 2020-12-10 Junji Ma , Jinbo Zhang , Ying Lin , Zhengjia Dai