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While deep learning has led to remarkable advances across diverse applications, it struggles in domains where the data distribution changes over the course of learning. In stark contrast, biological neural networks continually adapt to…

Machine Learning · Computer Science 2017-06-14 Friedemann Zenke , Ben Poole , Surya Ganguli

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

A growing body of research indicates that structural plasticity mechanisms are crucial for learning and memory consolidation. Starting from a simple phenomenological model, we exploit a mean-field approach to develop a theoretical framework…

Neurons and Cognition · Quantitative Biology 2024-06-19 Gianmarco Tiddia , Luca Sergi , Bruno Golosio

"You never forget how to ride a bike", -- but how is that possible? The brain is able to learn complex skills, stop the practice for years, learn other skills in between, and still retrieve the original knowledge when necessary. The…

Machine Learning · Computer Science 2024-01-26 Martin Barry , Wulfram Gerstner , Guillaume Bellec

Many mathematical models of synaptic plasticity have been proposed to explain the diversity of plasticity phenomena observed in biological organisms. These models range from simple interpretations of Hebb's postulate, which suggests that…

Neurons and Cognition · Quantitative Biology 2025-08-05 Danil Tyulmankov

How can we build agents that keep learning from experience, quickly and efficiently, after their initial training? Here we take inspiration from the main mechanism of learning in biological brains: synaptic plasticity, carefully tuned by…

Neural and Evolutionary Computing · Computer Science 2018-08-01 Thomas Miconi , Jeff Clune , Kenneth O. Stanley

Humans and animals have the ability to continually acquire, fine-tune, and transfer knowledge and skills throughout their lifespan. This ability, referred to as lifelong learning, is mediated by a rich set of neurocognitive mechanisms that…

Machine Learning · Computer Science 2019-02-12 German I. Parisi , Ronald Kemker , Jose L. Part , Christopher Kanan , Stefan Wermter

Continual learning aims to empower artificial intelligence (AI) with strong adaptability to the real world. For this purpose, a desirable solution should properly balance memory stability with learning plasticity, and acquire sufficient…

Machine Learning · Computer Science 2023-11-10 Liyuan Wang , Xingxing Zhang , Qian Li , Mingtian Zhang , Hang Su , Jun Zhu , Yi Zhong

Memory is often defined as the mental capacity of retaining information about facts, events, procedures and more generally about any type of previous experience. Memories are remembered as long as they influence our thoughts, feelings, and…

Neurons and Cognition · Quantitative Biology 2017-06-16 Stefano Fusi

Conventional intelligent systems based on deep neural network (DNN) models encounter challenges in achieving human-like continual learning due to catastrophic forgetting. Here, we propose a metaplasticity model inspired by human working…

Neural and Evolutionary Computing · Computer Science 2024-07-11 Suhee Cho , Hyeonsu Lee , Seungdae Baek , Se-Bum Paik

Recent studies have shown that metaplastic synapses can retain information longer than simple binary synapses and are beneficial for continual learning. In this paper, we explore the multistate metaplastic synapse characteristics in the…

Neural and Evolutionary Computing · Computer Science 2020-03-27 Fatima Tuz Zohora , Abdullah M. Zyarah , Nicholas Soures , Dhireesha Kudithipudi

To learn useful dynamics on long time scales, neurons must use plasticity rules that account for long-term, circuit-wide effects of synaptic changes. In other words, neural circuits must solve a credit assignment problem to appropriately…

Neurons and Cognition · Quantitative Biology 2019-05-30 Owen Marschall , Kyunghyun Cho , Cristina Savin

Deep artificial neural networks famously struggle to learn from non-stationary streams of data. Without dedicated mitigation strategies, continual learning is associated with continuous forgetting of previous tasks and a progressive loss of…

Neurons and Cognition · Quantitative Biology 2025-12-29 Suzanne van der Veldt , Gido M. van de Ven , Sanne Moorman , Guillaume Etter

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

To cope with real-world dynamics, an intelligent system needs to incrementally acquire, update, accumulate, and exploit knowledge throughout its lifetime. This ability, known as continual learning, provides a foundation for AI systems to…

Machine Learning · Computer Science 2024-02-07 Liyuan Wang , Xingxing Zhang , Hang Su , Jun Zhu

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

Neurons and Cognition · Quantitative Biology 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson

Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the…

Neurons and Cognition · Quantitative Biology 2015-05-05 Maurizio De Pittà , Nicolas Brunel , Andrea Volterra

The brain can learn to execute a wide variety of tasks quickly and efficiently. Nevertheless, most of the mechanisms that enable us to learn are unclear or incredibly complicated. Recently, considerable efforts have been made in…

Neural and Evolutionary Computing · Computer Science 2023-03-28 Mohammad Modiri

Unlike the brain, artificial neural networks, including state-of-the-art deep neural networks for computer vision, are subject to "catastrophic forgetting": they rapidly forget the previous task when trained on a new one. Neuroscience…

Neural and Evolutionary Computing · Computer Science 2021-06-09 Axel Laborieux , Maxence Ernoult , Tifenn Hirtzlin , Damien Querlioz

Continual learning refers to the ability of a biological or artificial system to seamlessly learn from continuous streams of information while preventing catastrophic forgetting, i.e., a condition in which new incoming information strongly…

Machine Learning · Computer Science 2019-07-04 German I. Parisi , Christopher Kanan
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