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Electron Microscopy (EM) image (or volume) segmentation has become significantly important in recent years as an instrument for connectomics. This paper proposes a novel agglomerative framework for EM segmentation. In particular, given an…

Computer Vision and Pattern Recognition · Computer Science 2015-06-09 Toufiq Parag , Anirban Chakraborty , Stephen Plaza , Lou Scheffer

Electron microscopic connectomics is an ambitious research direction with the goal of studying comprehensive brain connectivity maps by using high-throughput, nano-scale microscopy. One of the main challenges in connectomics research is…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Tran Minh Quan , David G. C. Hildebrand , Won-Ki Jeong

We consider the task of learning a classifier for semantic segmentation using weak supervision in the form of image labels which specify the object classes present in the image. Our method uses deep convolutional neural networks (CNNs) and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Qinbin Hou , Puneet Kumar Dokania , Daniela Massiceti , Yunchao Wei , Ming-Ming Cheng , Philip Torr

Three-dimensional medical image segmentation is a fundamental yet computationally demanding task due to the cubic growth of voxel processing and the redundant computation on homogeneous regions. To address these limitations, we propose…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

The emerging field of connectomics aims to unlock the mysteries of the brain by understanding the connectivity between neurons. To map this connectivity, we acquire thousands of electron microscopy (EM) images with nanometer-scale…

Quantitative Methods · Quantitative Biology 2016-04-04 Stephen M. Plaza , Stuart E. Berg

Transductive few-shot learning has recently triggered wide attention in computer vision. Yet, current methods introduce key hyper-parameters, which control the prediction statistics of the test batches, such as the level of class balance,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Long Zhou , Fereshteh Shakeri , Aymen Sadraoui , Mounir Kaaniche , Jean-Christophe Pesquet , Ismail Ben Ayed

We present a method combining affinity prediction with region agglomeration, which improves significantly upon the state of the art of neuron segmentation from electron microscopy (EM) in accuracy and scalability. Our method consists of a…

Computer Vision and Pattern Recognition · Computer Science 2020-07-29 Jan Funke , Fabian David Tschopp , William Grisaitis , Arlo Sheridan , Chandan Singh , Stephan Saalfeld , Srinivas C. Turaga

Automated segmentation of retinal blood vessels in label-free fundus images entails a pivotal role in computed aided diagnosis of ophthalmic pathologies, viz., diabetic retinopathy, hypertensive disorders and cardiovascular diseases. The…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Avisek Lahiri , Abhijit Guha Roy , Debdoot Sheet , Prabir Kumar Biswas

Tokenization is associated with many poorly understood shortcomings in language models (LMs), yet remains an important component for long sequence scaling purposes. This work studies how tokenization impacts model performance by analyzing…

Computation and Language · Computer Science 2025-04-15 Buu Phan , Brandon Amos , Itai Gat , Marton Havasi , Matthew Muckley , Karen Ullrich

Automated segmentation of anatomical sub-regions with high precision has become a necessity to enable the quantification and characterization of cells/ tissues in histology images. Currently, a machine learning model to analyze…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Hosein Barzekar , Hai Ngu , Han Hui Lin , Mohsen Hejrati , Steven Ray Valdespino , Sarah Chu , Baris Bingol , Somaye Hashemifar , Soumitra Ghosh

The exponential growth of Large Multimodal Models (LMMs) has driven advancements in cross-modal reasoning but at significant computational costs. In this work, we focus on visual language models. We highlight the redundancy and inefficiency…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Yasmine Omri , Parth Shroff , Thierry Tambe

Electroencephalography (EEG) enables non-invasive monitoring of brain activity across clinical and neurotechnology applications, yet building foundation models for EEG remains challenging due to \emph{differing electrode topologies} and…

Artificial Intelligence · Computer Science 2026-03-20 Danaé Broustail , Anna Tegon , Thorir Mar Ingolfsson , Yawei Li , Luca Benini

Autoregression in large language models (LLMs) has shown impressive scalability by unifying all language tasks into the next token prediction paradigm. Recently, there is a growing interest in extending this success to vision foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Shenghao Xie , Wenqiang Zu , Mingyang Zhao , Duo Su , Shilong Liu , Ruohua Shi , Guoqi Li , Shanghang Zhang , Lei Ma

Convolutional neural networks have primarily led 3D medical image segmentation but may be limited by small receptive fields. Transformer models excel in capturing global relationships through self-attention but are challenged by high…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Ao Chang , Jiajun Zeng , Ruobing Huang , Dong Ni

Although Deep Neural Networks have seen great success in recent years through various changes in overall architectures and optimization strategies, their fundamental underlying design remains largely unchanged. Computational neuroscience on…

Machine Learning · Computer Science 2019-12-17 Paul Bertens , Seong-Whan Lee

The task of medical image segmentation commonly involves an image reconstruction step to convert acquired raw data to images before any analysis. However, noises, artifacts and loss of information due to the reconstruction process are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Qiaoying Huang , Xiao Chen , Dimitris Metaxas , Mariappan S. Nadar

AI-enhanced segmentation of neuronal boundaries in electron microscopy (EM) images is crucial for automatic and accurate neuroinformatics studies. To enhance the limited generalization ability of typical deep learning frameworks for medical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Yuxiang An , Dongnan Liu , Weidong Cai

Video understanding has been considered as one critical step towards world modeling, which is an important long-term problem in AI research. Recently, multimodal foundation models have shown such potential via large-scale pretraining. These…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Boyu Chen , Siran Chen , Kunchang Li , Qinglin Xu , Yu Qiao , Yali Wang

Although deep encoder-decoder networks have achieved astonishing performance for mitochondria segmentation from electron microscopy (EM) images, they still produce coarse segmentations with lots of discontinuities and false positives.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-30 Zhimin Yuan , Jiajin Yi , Zhengrong Luo , Zhongdao Jia , Jialin Peng

Large-scale models have exhibited remarkable capabilities across diverse domains, including automated medical services and intelligent customer support. However, as most large models are trained on single-modality corpora, enabling them to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Hao Sun , Yu Song , Jiaqing Liu , Jihong Hu , Yen-Wei Chen , Lanfen Lin