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Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

Neurons and Cognition · Quantitative Biology 2018-11-16 Patrick Schwab , Walter Karlen

Head motion during functional Magnetic Resonance Imaging acquisition can significantly contaminate the neural signal and introduce spurious, distance-dependent changes in signal correlations. This can heavily confound studies of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-23 Vyom Raval , Kevin P. Nguyen , Albert Montillo

Lossy compression introduces complex compression artifacts, particularly blocking artifacts, ringing effects and blurring. Existing algorithms either focus on removing blocking artifacts and produce blurred output, or restore sharpened…

Computer Vision and Pattern Recognition · Computer Science 2016-08-10 Ke Yu , Chao Dong , Chen Change Loy , Xiaoou Tang

Deep learning (DL) has emerged as a tool for improving accelerated MRI reconstruction. A common strategy among DL methods is the physics-based approach, where a regularized iterative algorithm alternating between data consistency and a…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Burhaneddin Yaman , Seyed Amir Hossein Hosseini , Steen Moeller , Jutta Ellermann , Kâmil Uǧurbil , Mehmet Akçakaya

Parkinson's Disease (PD) is the second most common neurodegenerative disease in humans. PD is characterized by the gradual loss of dopaminergic neurons in the Substantia Nigra (SN). Counting the number of dopaminergic neurons in the SN is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Fatemeh Haghighi , Soumitra Ghosh , Hai Ngu , Sarah Chu , Han Lin , Mohsen Hejrati , Baris Bingol , Somaye Hashemifar

Quantitative Susceptibility Mapping (QSM) can estimate the underlying tissue magnetic susceptibility and reveal pathology. Current deep-learning-based approaches to solve the QSM inverse problem are restricted on fixed image resolution.…

Medical Physics · Physics 2019-08-02 Juan Liu , Kevin M. Koch

Automatic and accurate detection of anatomical landmarks is an essential operation in medical image analysis with a multitude of applications. Recent deep learning methods have improved results by directly encoding the appearance of the…

Computer Vision and Pattern Recognition · Computer Science 2021-05-20 Guang-Quan Zhou , Juzheng Miao , Xin Yang , Rui Li , En-Ze Huo , Wenlong Shi , Yuhao Huang , Jikuan Qian , Chaoyu Chen , Dong Ni

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

The application of deep learning to build accurate predictive models from functional neuroimaging data is often hindered by limited dataset sizes. Though data augmentation can help mitigate such training obstacles, most data augmentation…

Machine Learning · Computer Science 2019-10-21 Kevin P. Nguyen , Cherise Chin Fatt , Alex Treacher , Cooper Mellema , Madhukar H. Trivedi , Albert Montillo

One of the most catastrophic neurological disorders worldwide is Parkinson's Disease. Along with it, the treatment is complicated and abundantly expensive. The only effective action to control the progression is diagnosing it in the early…

Machine Learning · Computer Science 2023-10-23 Md. Taufiqul Haque Khan Tusar , Md. Touhidul Islam , Abul Hasnat Sakil

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

Machine Learning · Computer Science 2021-01-13 Alexander Lavin

Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…

Magnetic Resonance Fingerprinting (MRF) and other highly accelerated transient-state parameter mapping techniques enable simultaneous quantification of multiple tissue properties, but often suffer from aliasing artifacts due to compressed…

Early detection of cognitive impairment is critical for timely diagnosis and intervention, yet infrequent clinical assessments often lack the sensitivity and temporal resolution to capture subtle cognitive declines in older adults. Passive…

Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Maria Frasca , Davide La Torre , Gabriella Pravettoni , Ilaria Cutica

In this work we reduce undersampling artefacts in two-dimensional ($2D$) golden-angle radial cine cardiac MRI by applying a modified version of the U-net. We train the network on $2D$ spatio-temporal slices which are previously extracted…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Andreas Kofler , Marc Dewey , Tobias Schaeffter , Christian Wald , Christoph Kolbitsch

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

Shortening acquisition time and reducing motion artifacts are the most critical challenges in magnetic resonance imaging (MRI). Deep learning-based image restoration has emerged as a promising solution capable of generating high-resolution…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Hao Li , Jianan Liu , Marianne Schell , Tao Huang , Arne Lauer , Katharina Schregel , Jessica Jesser , Dominik F Vollherbst , Martin Bendszus , Sabine Heiland , Tim Hilgenfeld

Traditional approaches for molecular imaging of Parkinson's disease (PD) in vivo require radioactive isotopes, lengthy scan times, or deliver only low spatial resolution. Recent advances in saturation transfer-based PD magnetic resonance…

Medical Physics · Physics 2025-12-24 Hagar Shmuely , Michal Rivlin , Or Perlman

Deep learning, a cutting-edge machine learning approach, outperforms traditional machine learning in identifying intricate structures in complex high-dimensional data, particularly in the domain of healthcare. This study focuses on…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Nida Nasir , Muneeb Ahmed , Neda Afreen , Mustafa Sameer
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