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Data-driven autonomous driving motion generation tasks are frequently impacted by the limitations of dataset size and the domain gap between datasets, which precludes their extensive application in real-world scenarios. To address this…

Robotics · Computer Science 2024-11-04 Wei Wu , Xiaoxin Feng , Ziyan Gao , Yuheng Kan

Recent advances in agentic AI have led to systems capable of autonomous task execution and language-based reasoning, yet their spatial reasoning abilities remain limited and underexplored, largely constrained to symbolic and sequential…

Artificial Intelligence · Computer Science 2025-09-12 Bui Duc Manh , Soumyaratna Debnath , Zetong Zhang , Shriram Damodaran , Arvind Kumar , Yueyi Zhang , Lu Mi , Erik Cambria , Lin Wang

Computational systems biology has provided plenty of insights into cell biology. Early on, the focus was on reaction networks between molecular species. Spatial distribution only began to be considered mostly within the last decade.…

Quantitative Methods · Quantitative Biology 2016-05-13 Atsushi Miyauchi , Kazunari Iwamoto , Satya Nanda Vel Arjunan , Koichi Takahashi

Temporally and spatially resolved measurements of protein transport inside cells provide important clues to the functional architecture and dynamics of biological systems. Fluorescence Recovery After Photobleaching (FRAP) technique has been…

Subcellular Processes · Quantitative Biology 2009-03-04 George D. Tsibidis

Predicting spatio-temporal traffic flow presents significant challenges due to complex interactions between spatial and temporal factors. Existing approaches often address these dimensions in isolation, neglecting their critical…

Artificial Intelligence · Computer Science 2024-11-15 Weilin Ruan , Wenzhuo Wang , Siru Zhong , Wei Chen , Li Liu , Yuxuan Liang

This limited review is intended as an introduction to the fast growing subject of mathematical modelling of cell metabolism and its biochemical pathways, and more precisely on pathways linked to apoptosis of cancerous cells. Some basic…

Molecular Networks · Quantitative Biology 2013-10-03 Bernard Ycart , Frédéric Pont , Jean-Jacques Fournié

In resource-constrained environments, one can employ spatial multiplexing cameras to acquire a small number of measurements of a scene, and perform effective reconstruction or high-level inference using purely data-driven neural networks.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Suhas Lohit , Rajhans Singh , Kuldeep Kulkarni , Pavan Turaga

Self-localization during navigation with noisy sensors in an ambiguous world is computationally challenging, yet animals and humans excel at it. In robotics, Simultaneous Location and Mapping (SLAM) algorithms solve this problem though…

Neurons and Cognition · Quantitative Biology 2016-12-15 Ingmar Kanitscheider , Ila Fiete

Metabolic pathways describe chains of enzymatic reactions. Their modelling is a key point to understand living systems. An enzymatic reaction is an interaction between one or several metabolites (substrates) and an enzyme (simple protein or…

Subcellular Processes · Quantitative Biology 2009-01-27 Charles Lales , N. Parisey , Jean-Pierre Mazat , Marie Beurton-Aimar

Most V2X (Vehicle-to-Everything) applications rely on broadcasting awareness messages known as CAM (Cooperative Awareness Messages) in ETSI or BSM (Basic Safety Message) in SAE standards. A large number of studies have been devoted to…

Networking and Internet Architecture · Computer Science 2020-05-19 Rafael Molina-Masegosa , Miguel Sepulcre , Javier Gozalvez , Friedbert Berens , Vincent Martinez

Molecular signalling in living cells occurs at low copy numbers and is thereby inherently limited by the noise imposed by thermal diffusion. The precision at which biochemical receptors can count signalling molecules is intimately related…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler

A hallmark of a plethora of intracellular signaling pathways is the spatial separation of activation and deactivation processes that potentially results in precipitous gradients of activated proteins. The classical Metabolic Control…

Analysis of PDEs · Mathematics 2007-05-23 Mark A. Peletier , Hans V. Westerhoff , Boris N. Kholodenko

The response of adult human bone marrow stromal stem cells to surface topographies generated through femtosecond laser machining can be predicted by a deep neural network. The network is capable of predicting cell response to a…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Benita S. Mackay , Matthew Praeger , James A. Grant-Jacob , Janos Kanczler , Robert W. Eason , Richard O. C. Oreffo , Ben Mills

We address the problem of applying Task and Motion Planning (TAMP) in real world environments. TAMP combines symbolic and geometric reasoning to produce sequential manipulation plans, typically specified as joint-space trajectories, which…

Robotics · Computer Science 2020-05-06 Toki Migimatsu , Jeannette Bohg

The network of biochemical reactions inside living organisms is characterized by an overwhelming complexity which stems from the sheer number of reactions and from the complicated topology of biochemical cycles. However the high speed of…

Biological Physics · Physics 2009-10-30 Edoardo Milotti , Alessio Del Fabbro , Roberto Chignola

We present a simple and robust technique to extract kinetic rate models and thermodynamic quantities from single molecule time traces. SMACKS (Single Molecule Analysis of Complex Kinetic Sequences) is a maximum likelihood approach that…

Quantitative Methods · Quantitative Biology 2022-03-10 Sonja Schmid , Markus Götz , Thorsten Hugel

Many biological, physical, and social interactions have a particular dependence on where they take place. In living cells, protein movement between the nucleus and cytoplasm affects cellular response (i.e., proteins must be present in the…

Molecular Networks · Quantitative Biology 2012-10-11 Heather A. Harrington , Elisenda Feliu , Carsten Wiuf , Michael M. P. Stumpf

Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…

Dynamical Systems · Mathematics 2022-08-12 Shuang Liu , Li-Tien Cheng , Bo Li

We discuss and predict the evolution of Simultaneous Localisation and Mapping (SLAM) into a general geometric and semantic `Spatial AI' perception capability for intelligent embodied devices. A big gap remains between the visual perception…

Artificial Intelligence · Computer Science 2018-04-02 Andrew J. Davison

This chapter provides a brief introduction to the theory and practice of spatial stochastic simulations. It begins with an overview of different methods available for biochemical simulations highlighting their strengths and limitations.…

Quantitative Methods · Quantitative Biology 2018-10-02 Sanjana Gupta , Jacob Czech , Robert Kuczewski , Thomas M. Bartol , Terrence J. Sejnowski , Robin E. C. Lee , James R. Faeder