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Generators of space-time dynamics in bioimaging have become essential to build ground truth datasets for image processing algorithm evaluation such as biomolecule detectors and trackers, as well as to generate training datasets for deep…

Subcellular Processes · Quantitative Biology 2023-03-14 Lisa Balsollier , Frédéric Lavancier , Jean Salamero , Charles Kervrann

The importance of stochasticity within biological systems has been shown repeatedly during the last years and has raised the need for efficient stochastic tools. We present SABRE, a tool for stochastic analysis of biochemical reaction…

Computational Engineering, Finance, and Science · Computer Science 2010-05-18 Frederic Didier , Thomas A. Henzinger , Maria Mateescu , Verena Wolf

We cast the metabolism of interacting cells within a statistical mechanics framework considering both, the actual phenotypic capacities of each cell and its interaction with its neighbors. Reaction fluxes will be the components of…

Molecular Networks · Quantitative Biology 2020-04-08 Jorge Fernandez-de-Cossio-Diaz , Roberto Mulet

The paper presents an algorithm, called Self-Morphing Adaptive Replanning Tree (SMART), that facilitates fast replanning in dynamic environments. SMART performs risk based tree-pruning if the current path is obstructed by nearby moving…

Robotics · Computer Science 2023-09-22 Zongyuan Shen , James P. Wilson , Shalabh Gupta , Ryan Harvey

Understanding the dynamic nature of biological systems is fundamental to deciphering cellular behavior, developmental processes, and disease progression. Single-cell RNA sequencing (scRNA-seq) has provided static snapshots of gene…

Quantitative Methods · Quantitative Biology 2025-05-02 Zhenyi Zhang , Yuhao Sun , Qiangwei Peng , Tiejun Li , Peijie Zhou

Our brain has an inner global positioning system which enables us to sense and navigate 3D spaces in real time. Can mobile robots replicate such a biological feat in a dynamic environment? We introduce the first spatial reasoning framework…

Robotics · Computer Science 2025-05-20 Pengdi Huang , Mingyang Wang , Huan Tian , Minglun Gong , Hao Zhang , Hui Huang

Visual navigation by mobile robots is classically tackled through SLAM plus optimal planning, and more recently through end-to-end training of policies implemented as deep networks. While the former are often limited to waypoint planning,…

Artificial Intelligence · Computer Science 2021-11-30 Assem Sadek , Guillaume Bono , Boris Chidlovskii , Christian Wolf

3D semantic maps have played an increasingly important role in high-precision robot localization and scene understanding. However, real-time construction of semantic maps requires mobile edge devices with extremely high computing power,…

Robotics · Computer Science 2024-12-03 Jiaxing Zhang , Luosong Guo , Kun Zhu , Houming Qiu

Cellular identity and function are linked to both their intrinsic genomic makeup and extrinsic spatial context within the tissue microenvironment. Spatial transcriptomics (ST) offers an unprecedented opportunity to study this, providing in…

Machine Learning · Computer Science 2026-02-16 Rui Yan , Xiaohan Xing , Xun Wang , Zixia Zhou , Md Tauhidul Islam , Lei Xing

Biochemical signalling cascades transduce extracellular stimuli into cellular responses through sequences of discrete, node-to-node activations. While signal fidelity depends critically on local interaction kinetics, the mechanisms…

Dynamical Systems · Mathematics 2026-04-20 Chathranee Jayathilaka , Mark B. Flegg

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

Tissues and Organs · Quantitative Biology 2019-02-14 Melinda Liu Perkins , Murat Arcak

Advances in bioengineering and biomedicine demand a deep understanding of the dynamic behavior of biological systems, ranging from protein pathways to complex cellular processes. Biological networks like gene regulatory networks and protein…

Biomolecules · Quantitative Biology 2023-10-31 Mayalen Etcheverry , Michael Levin , Clément Moulin-Frier , Pierre-Yves Oudeyer

We present Scalable Multi-Agent Realistic Testbed (SMART), a realistic and efficient software tool for evaluating Multi-Agent Path Finding (MAPF) algorithms. MAPF focuses on planning collision-free paths for a group of robots. While…

Visual understanding of 3D environments in real-time, at low power, is a huge computational challenge. Often referred to as SLAM (Simultaneous Localisation and Mapping), it is central to applications spanning domestic and industrial…

The stochastic simulation of large-scale biochemical reaction networks is of great importance for systems biology since it enables the study of inherently stochastic biological mechanisms at the whole cell scale. Stochastic Simulation…

Molecular Networks · Quantitative Biology 2017-10-30 Elias S. Manolakos , Elias Kouskoumvekakis

This study introduces and addresses the critical challenge of traffic load estimation in cell switching within vertical heterogeneous networks. The effectiveness of cell switching is significantly limited by the lack of accurate traffic…

Systems and Control · Electrical Eng. & Systems 2026-01-19 Maryam Salamatmoghadasi , Metin Ozturk , Halim Yanikomeroglu

Biological neurons and their in-silico emulations for neuromorphic artificial intelligence (AI) use extraordinarily energy-efficient mechanisms, such as spike-based communication and local synaptic plasticity. It remains unclear whether…

Neural and Evolutionary Computing · Computer Science 2021-06-17 Timoleon Moraitis , Abu Sebastian , Evangelos Eleftheriou

Cellular traffic forecasting is a critical task that enables network operators to efficiently allocate resources and address anomalies in rapidly evolving environments. The exponential growth of data collected from base stations poses…

Machine Learning · Computer Science 2025-08-14 Theodoros Tsiolakis , Nikolaos Pavlidis , Vasileios Perifanis , Pavlos Efraimidis

In this paper, we propose using deep neural architectures (i.e., vision transformers and ResNet) as heuristics for sequential decision-making in robotic manipulation problems. This formulation enables predicting the subset of objects that…

Robotics · Computer Science 2023-08-02 Hongyou Zhou , Ingmar Schubert , Marc Toussaint , Ozgur S. Oguz

In this work we show how we can build a technology platform for cognitive imaging sensors using recent advances in recurrent neural network architectures and training methods inspired from biology. We demonstrate learning and processing…

Computer Vision and Pattern Recognition · Computer Science 2018-03-26 Samiran Ganguly , Yunfei Gu , Mircea R. Stan , Avik W. Ghosh