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Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake

Intracranial aneurysms (IAs) are serious cerebrovascular lesions found in approximately 5\% of the general population. Their rupture may lead to high mortality. Current methods for assessing IA risk focus on morphological and…

Infrared imagery enables temperature-based scene understanding using passive sensors, particularly under conditions of low visibility where traditional RGB imaging fails. Yet, developing downstream vision models for infrared applications is…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Kai A. Horstmann , Maxim Clouser , Kia Khezeli

If modern computers are sometimes superior to humans in some specialized tasks such as playing chess or browsing a large database, they can't beat the efficiency of biological vision for such simple tasks as recognizing and following an…

Neurons and Cognition · Quantitative Biology 2009-11-13 Laurent Perrinet

Fluorescence microscopy is widely employed for the analysis of living biological samples; however, the utility of the resulting recordings is frequently constrained by noise, temporal variability, and inconsistent visualisation of signals…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Hassan Eshkiki , Sarah Costa , Mostafa Mohammadpour , Farinaz Tanhaei , Christopher H. George , Fabio Caraffini

In many real-world scientific problems, generating ground truth (GT) for supervised learning is almost impossible. The causes include limitations imposed by scientific instrument, physical phenomenon itself, or the complexity of modeling.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Arif Ahmed Sekh , Ida S. Opstad , Rohit Agarwal , Asa Birna Birgisdottir , Truls Myrmel , Balpreet Singh Ahluwalia , Krishna Agarwal , Dilip K. Prasad

CPU simulators are vital for computer architecture research, primarily for estimating performance under different programs. This poses challenges for fast and accurate simulation of modern CPUs, especially in multi-core systems. Modern CPU…

Performance · Computer Science 2025-10-14 Buqing Xu , Jianfeng Zhu , Yichi Zhang , Qinyi Cai , Guanhua Li , Shaojun Wei , Leibo Liu

In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to detect neural peak activities.…

Long-form clinical videos are central to visual evidence-based decision-making, with growing importance for applications such as surgical robotics and related settings. However, current multimodal large language models typically process…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Wenjie Li , Yujie Zhang , Haoran Sun , Xingqi He , Hongcheng Gao , Chenglong Ma , Ming Hu , Guankun Wang , Shiyi Yao , Renhao Yang , Hongliang Ren , Lei Wang , Junjun He , Yankai Jiang

Computational neuroscience is being revolutionized with the advent of multi-electrode arrays that provide real-time, dynamic, perspectives into brain function. Mining event streams from these chips is critical to understanding the firing…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-05-15 Yong Cao , Debprakash Patnaik , Sean Ponce , Jeremy Archuleta , Patrick Butler , Wu-chun Feng , Naren Ramakrishnan

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

While recent advances in deep learning have led to significant improvements in facial expression classification (FEC), a major challenge that remains a bottleneck for the widespread deployment of such systems is their high architectural and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 James Ren Hou Lee , Linda Wang , Alexander Wong

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Deep neural network is an effective choice to automatically recognize human actions utilizing data from various wearable sensors. These networks automate the process of feature extraction relying completely on data. However, various noises…

Signal Processing · Electrical Eng. & Systems 2021-01-05 Tanvir Mahmud , A. Q. M. Sazzad Sayyed , Shaikh Anowarul Fattah , Sun-Yuan Kung

Observing system uncertainty experiments (OSUEs) have been recently proposed as a cost-effective way to perform probabilistic assessment of retrievals for NASA's Orbiting Carbon Observatory-2 (OCO-2) mission. One important component in the…

Applications · Statistics 2020-11-03 Pulong Ma , Anirban Mondal , Bledar Konomi , Jonathan Hobbs , Joon Song , Emily Kang

Spike sorting is a class of algorithms used in neuroscience to attribute the time occurences of particular electric signals, called action potential or spike, to neurons. We rephrase this problem as a particular optimization problem : Lasso…

Statistics Theory · Mathematics 2022-04-12 Laurent Dragoni , Rémi Flamary , Karim Lounici , Patricia Reynaud-Bouret

For transient sources with timescales of 1-100 seconds, standardized imaging for all observations at each time step become impossible as large modern interferometers produce significantly large data volumes in this observation time frame.…

Instrumentation and Methods for Astrophysics · Physics 2022-04-06 Xia Zhang , Foivos I. Diakogiannis , Richard Dodson , Andreas Wicenec

Recent efforts in neuroscience research seek to obtain detailed anatomical neuronal wiring maps as well as information on how neurons in these networks engage in dynamic activities. Although the entire connectivity map of the nervous system…

Neurons and Cognition · Quantitative Biology 2014-06-09 Tina Schrödel , Robert Prevedel , Karin Aumayr , Manuel Zimmer , Alipasha Vaziri

Process simulation is gaining attention for its ability to assess potential performance improvements and risks associated with business process changes. The existing literature presents various techniques, generally grounded in process…

Artificial Intelligence · Computer Science 2024-06-26 Rafael S. Oyamada , Gabriel M. Tavares , Sylvio Barbon Junior , Paolo Ceravolo

In cryo-electron microscopy, accurate particle localization and classification are imperative. Recent deep learning solutions, though successful, require extensive training data sets. The protracted generation time of physics-based models,…

Machine Learning · Computer Science 2025-02-20 Pavol Harar , Lukas Herrmann , Philipp Grohs , David Haselbach