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Understanding cell identity is an important task in many biomedical areas. Expression patterns of specific marker genes have been used to characterize some limited cell types, but exclusive markers are not available for many cell types. A…

Motivation: PCR is more economical and quicker than Next Generation Sequencing for detecting target organisms, with primer design being a critical step. In epidemiology with rapidly mutating viruses, designing effective primers is…

Genomics · Quantitative Biology 2025-12-18 Hanyu Wang , Emmanuel K. Tsinda , Anthony J. Dunn , Francis Chikweto , Alain B. Zemkoho

The world is still overwhelmed by the spread of the COVID-19 virus. With over 250 Million infected cases as of November 2021 and affecting 219 countries and territories, the world remains in the pandemic period. Detecting COVID-19 using the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Gargi Desai , Nelly Elsayed , Zag Elsayed , Murat Ozer

The high-content image-based assay is commonly leveraged for identifying the phenotypic impact of genetic perturbations in biology field. However, a persistent issue remains unsolved during experiments: the interferential technical noise…

Image and Video Processing · Electrical Eng. & Systems 2022-12-09 Sen Yang , Tao Shen , Yuqi Fang , Xiyue Wang , Jun Zhang , Wei Yang , Junzhou Huang , Xiao Han

The application of machine learning techniques to the medical domain is especially challenging due to the required level of precision and the incurrence of huge risks of minute errors. Employing these techniques to a more complex subdomain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Ekta Gavas , Kaustubh Olpadkar

In software, a vulnerability is a defect in a program that attackers might utilize to acquire unauthorized access, alter system functions, and acquire information. These vulnerabilities arise from programming faults, design flaws, incorrect…

Software Engineering · Computer Science 2024-11-28 Md. Fahim Sultan , Tasmin Karim , Md. Shazzad Hossain Shaon , Mohammad Wardat , Mst Shapna Akter

Humans are able to categorize images very efficiently, in particular to detect the presence of an animal very quickly. Recently, deep learning algorithms based on convolutional neural networks (CNNs) have achieved higher than human accuracy…

Neurons and Cognition · Quantitative Biology 2023-06-01 Jean-Nicolas Jérémie , Laurent U Perrinet

Aggregation-based assays, using micro- and nano-particles have been widely accepted as an efficient and cost-effective bio-sensing tool, particularly in microbiology, where particle clustering events are used as a metric to infer the…

Instrumentation and Detectors · Physics 2018-12-31 Yichen Wu , Aniruddha Ray , Qingshan Wei , Alborz Feizi , Xin Tong , Eva Chen , Yi Luo , Aydogan Ozcan

Deep generative networks in recent years have reinforced the need for caution while consuming various modalities of digital information. One avenue of deepfake creation is aligned with injection and removal of tumors from medical scans.…

Computer Vision and Pattern Recognition · Computer Science 2022-04-08 Siddharth Solaiyappan , Yuxin Wen

Among all animals, mosquitoes are responsible for the most deaths worldwide. Interestingly, not all types of mosquitoes spread diseases, but rather, a select few alone are competent enough to do so. In the case of any disease outbreak, an…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Mona Minakshi , Pratool Bharti , Willie B. McClinton , Jamshidbek Mirzakhalov , Ryan M. Carney , Sriram Chellappan

In this work, we investigate the performance across multiple classification models to classify chest X-ray images into four categories of COVID-19, pneumonia, tuberculosis (TB), and normal cases. We leveraged transfer learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Alanna Hazlett , Naomi Ohashi , Timothy Rodriguez , Sodiq Adewole

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

The aim of this study is to propose an alternative and hybrid solution method for diagnosing the disease from histopathology images taken from animals with paratuberculosis and intact intestine. In detail, the hybrid method is based on…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Nilgun Sengoz , Tuncay Yigit , Ozlem Ozmen , Ali Hakan Isik

The introduction of deep learning and transfer learning techniques in fields such as computer vision allowed a leap forward in the accuracy of image classification tasks. Currently there is only limited use of such techniques in…

Machine Learning · Computer Science 2019-07-03 Axel Uran , Coert van Gemeren , Rosanne van Diepen , Ricardo Chavarriaga , José del R. Millán

Identifying areas in a landscape where individuals have a higher likelihood of disease infection is key to managing diseases. Unlike conventional methods relying on ecological assumptions, we perform a novel epidemiological tomography for…

The spread of microbial infections is governed by the self-organization of bacteria on surfaces. Limitations of live imaging techniques make collective behaviors in clinically relevant systems challenging to quantify. Here, novel…

Biological Physics · Physics 2024-07-19 Vincent Hickl , Abid Khan , René M. Rossi , Bruno F. B. Silva , Katharina Maniura-Weber

Weakly-supervised learning under image-level labels supervision has been widely applied to semantic segmentation of medical lesions regions. However, 1) most existing models rely on effective constraints to explore the internal…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Jiahua Dong , Yang Cong , Gan Sun , Dongdong Hou

Background and Objective: During pandemics, the use of artificial intelligence (AI) approaches combined with biomedical science play a significant role in reducing the burden on the healthcare systems and physicians. The rapid increment in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-30 Mansi Gupta , Aman Swaraj , Karan Verma

With the rapid proliferation and increased sophistication of malicious software (malware), detection methods no longer rely only on manually generated signatures but have also incorporated more general approaches like machine learning…

Machine Learning · Computer Science 2020-01-24 Felipe N. Ducau , Ethan M. Rudd , Tad M. Heppner , Alex Long , Konstantin Berlin

Controlling crystalline material defects is crucial, as they affect properties of the material that may be detrimental or beneficial for the final performance of a device. Defect analysis on the sub-nanometer scale is enabled by…

Materials Science · Physics 2021-06-03 Nik Dennler , Antonio Foncubierta-Rodriguez , Titus Neupert , Marilyne Sousa