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Background and objective: Employing deep learning models in critical domains such as medical imaging poses challenges associated with the limited availability of training data. We present a strategy for improving the performance and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Eva Pachetti , Sotirios A. Tsaftaris , Sara Colantonio

Self-supervised contrastive learning has demonstrated great potential in learning visual representations. Despite their success in various downstream tasks such as image classification and object detection, self-supervised pre-training for…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Di Wu , Siyuan Li , Zelin Zang , Stan Z. Li

Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Laura J. Tafe , Yevgeniy A. Linnik , Louis J. Vaickus , Naofumi Tomita , Saeed Hassanpour

Weakly-supervised learning (WSL) has recently triggered substantial interest as it mitigates the lack of pixel-wise annotations. Given global image labels, WSL methods yield pixel-level predictions (segmentations), which enable to interpret…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

We consider preoperative prediction of thyroid cancer based on ultra-high-resolution whole-slide cytopathology images. Inspired by how human experts perform diagnosis, our approach first identifies and classifies diagnostic image regions…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 David Dov , Shahar Kovalsky , Jonathan Cohen , Danielle Range , Ricardo Henao , Lawrence Carin

Recent advancements in self-supervised learning have demonstrated that effective visual representations can be learned from unlabeled images. This has led to increased interest in applying self-supervised learning to the medical domain,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Xiangyi Yan , Junayed Naushad , Chenyu You , Hao Tang , Shanlin Sun , Kun Han , Haoyu Ma , James Duncan , Xiaohui Xie

Accurate detection of pulmonary nodules with high sensitivity and specificity is essential for automatic lung cancer diagnosis from CT scans. Although many deep learning-based algorithms make great progress for improving the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Jingya Liu , Liangliang Cao , Oguz Akin , Yingli Tian

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Bodong Zhang , Xiwen Li , Hamid Manoochehri , Xiaoya Tang , Deepika Sirohi , Beatrice S. Knudsen , Tolga Tasdizen

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Jinqiu Chen , Huyan Xu

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

The goal of our research is to develop methods advancing automatic visual recognition. In order to predict the unique or multiple labels associated to an image, we study different kind of Deep Neural Networks architectures and methods for…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Rémi Cadène , Nicolas Thome , Matthieu Cord

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

Deep models have been widely and successfully used in image manipulation detection, which aims to classify tampered images and localize tampered regions. Most existing methods mainly focus on extracting global features from tampered images,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Yuyuan Zeng , Bowen Zhao , Shanzhao Qiu , Tao Dai , Shu-Tao Xia

Weakly supervised image segmentation with image-level labels has drawn attention due to the high cost of pixel-level annotations. Traditional methods using Class Activation Maps (CAMs) often highlight only the most discriminative regions,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qingchen Tang , Lei Fan , Maurice Pagnucco , Yang Song

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Deriving interpretable prognostic features from deep-learning-based prognostic histopathology models remains a challenge. In this study, we developed a deep learning system (DLS) for predicting disease specific survival for stage II and III…

Cancer diagnosis and prognosis primarily depend on clinical parameters such as age and tumor grade, and are increasingly complemented by molecular data, such as gene expression, from tumor sequencing. However, sequencing is costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Max Hallemeesch , Marija Pizurica , Paloma Rabaey , Olivier Gevaert , Thomas Demeester , Kathleen Marchal

Pathology images are considered the ``gold standard" for cancer diagnosis and treatment, with gigapixel images providing extensive tissue and cellular information. Existing methods fail to simultaneously extract global structural and local…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Haoming Luo , Xiaotian Yu , Shengxuming Zhang , Jiabin Xia , Yang Jian , Yuning Sun , Liang Xue , Mingli Song , Jing Zhang , Xiuming Zhang , Zunlei Feng
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