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Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Hanyu Chen , Zhixiu Hao , Lin Guo , Liying Xiao

Low-dose computed tomography (CT) plays a significant role in reducing the radiation risk in clinical applications. However, lowering the radiation dose will significantly degrade the image quality. With the rapid development and wide…

Image and Video Processing · Electrical Eng. & Systems 2022-12-08 Bin Huang , Liu Zhang , Shiyu Lu , Boyu Lin , Weiwen Wu , Qiegen Liu

Sparse views X-ray computed tomography has emerged as a contemporary technique to mitigate radiation dose. Because of the reduced number of projection views, traditional reconstruction methods can lead to severe artifacts. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Liutao Yang , Jiahao Huang , Guang Yang , Daoqiang Zhang

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

Breast cancer is the most prevalent cancer among women worldwide, and early detection is crucial for reducing its mortality rate and improving quality of life. Dedicated breast computed tomography (CT) scanners offer better image quality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Wenjun Xia , Hsin Wu Tseng , Chuang Niu , Wenxiang Cong , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Srinivasan Vedantham , Ge Wang

The reconstruction of X-rays CT images from sparse or limited-angle geometries is a highly challenging task. The lack of data typically results in artifacts in the reconstructed image and may even lead to object distortions. For this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Davide Evangelista , Pasquale Cascarano , Elena Loli Piccolomini

Diffusion models face significant challenges when employed for large-scale medical image reconstruction in real practice such as 3D Computed Tomography (CT). Due to the demanding memory, time, and data requirements, it is difficult to train…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Bowen Song , Jason Hu , Zhaoxu Luo , Jeffrey A. Fessler , Liyue Shen

Medical image reconstruction with pre-trained score-based generative models (SGMs) has advantages over other existing state-of-the-art deep-learned reconstruction methods, including improved resilience to different scanner setups and…

Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Sho Ozaki , Shizuo Kaji , Toshikazu Imae , Kanabu Nawa , Hideomi Yamashita , Keiichi Nakagawa

The currently limited quality of accelerated cardiac cine reconstruction may potentially be improved by the emerging diffusion models, but the clinically unacceptable long processing time poses a challenge. We aim to develop a clinically…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Shihan Qiu , Shaoyan Pan , Yikang Liu , Lin Zhao , Jian Xu , Qi Liu , Terrence Chen , Eric Z. Chen , Xiao Chen , Shanhui Sun

Attenuation artifacts remain a significant challenge in cardiac Myocardial Perfusion Imaging (MPI) using Single-Photon Emission Computed Tomography (SPECT), often compromising diagnostic accuracy and reducing clinical interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Trung Kien Pham , Hoang Minh Vu , Anh Duc Chu , Dac Thai Nguyen , Trung Thanh Nguyen , Thao Nguyen Truong , Mai Hong Son , Thanh Trung Nguyen , Phi Le Nguyen

For single source helical Computed Tomography (CT), both Filtered-Back Projection (FBP) and statistical iterative reconstruction have been investigated. However for dual source CT with flying focal spot (DS-FFS CT), statistical iterative…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Xiao Wang , Robert D. MacDougall , Peng Chen , Charles A. Bouman , Simon K. Warfield

Accurate multi-slice reconstruction from limited measurement data is crucial to speed up the acquisition process in medical and scientific imaging. However, it remains challenging due to the ill-posed nature of the problem and the high…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Laurentius Valdy , Richard D. Paul , Alessio Quercia , Zhuo Cao , Xuan Zhao , Hanno Scharr , Arya Bangun

Recent score-based diffusion models (SBDMs) show promising results in unpaired image-to-image translation (I2I). However, existing methods, either energy-based or statistically-based, provide no explicit form of the interfered intermediate…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Shikun Sun , Longhui Wei , Junliang Xing , Jia Jia , Qi Tian

Super Resolution (SR) plays a critical role in computer vision, particularly in medical imaging, where hardware and acquisition time constraints often result in low spatial and temporal resolution. While diffusion models have been applied…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Vishal Dubey

Cardiac Magnetic Resonance (CMR) imaging is a critical tool for diagnosing and managing cardiovascular disease, yet its utility is often limited by the sparse acquisition of 2D short-axis slices, resulting in incomplete volumetric…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Niklas Bubeck , Suprosanna Shit , Chen Chen , Can Zhao , Pengfei Guo , Dong Yang , Georg Zitzlsberger , Daguang Xu , Bernhard Kainz , Daniel Rueckert , Jiazhen Pan

This paper explores the use of score-based diffusion models for Bayesian image reconstruction. Diffusion models are an efficient tool for generative modeling. Diffusion models can also be used for solving image reconstruction problems. We…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Michael T. McCann , Hyungjin Chung , Jong Chul Ye , Marc L. Klasky

Coronary artery calcium (CAC) scoring from chest CT is a well-established tool to stratify and refine clinical cardiovascular disease risk estimation. CAC quantification relies on the accurate delineation of calcified lesions, but is…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Xinran Gong , Gorkem Durak , Halil Ertugrul Aktas , Vedat Cicek , Jinkui Hao , Ulas Bagci , Nilay S. Shah , Bo Zhou

ECG-gated cine imaging in breath-hold enables high-quality diagnostics in most patients, arrhythmia and inability to hold breath, however, can severely corrupt outcomes. Real-time cardiac MRI in free-breathing leverages robust and faster…

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader