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Medical question answering (QA) requires extensive access to domain-specific knowledge. A promising direction is to enhance large language models (LLMs) with external knowledge retrieved from medical corpora or parametric knowledge stored…

Computation and Language · Computer Science 2025-10-22 Lei Li , Xiao Zhou , Yingying Zhang , Xian Wu

We explore state-of-the-art neural models for question answering on electronic medical records and improve their ability to generalize better on previously unseen (paraphrased) questions at test time. We enable this by learning to predict…

Artificial Intelligence · Computer Science 2021-02-23 Bhanu Pratap Singh Rawat , Wei-Hung Weng , So Yeon Min , Preethi Raghavan , Peter Szolovits

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

Computation and Language · Computer Science 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Question and answer generation (QAG) consists of generating a set of question-answer pairs given a context (e.g. a paragraph). This task has a variety of applications, such as data augmentation for question answering (QA) models,…

Computation and Language · Computer Science 2023-05-29 Asahi Ushio , Fernando Alva-Manchego , Jose Camacho-Collados

Biomedical question-answering (QA) has gained increased attention for its capability to provide users with high-quality information from a vast scientific literature. Although an increasing number of biomedical QA datasets has been recently…

Computation and Language · Computer Science 2021-02-17 Gabriele Pergola , Elena Kochkina , Lin Gui , Maria Liakata , Yulan He

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

Large language models (LLMs) demonstrate remarkable text comprehension and generation capabilities but often lack the ability to utilize up-to-date or domain-specific knowledge not included in their training data. To address this gap, we…

Computation and Language · Computer Science 2025-09-26 Bo Zhang , Hui Ma , Dailin Li , Jian Ding , Jian Wang , Bo Xu , HongFei Lin

Question answering (QA) has become an important application in the advanced development of large language models. General pre-trained large language models for question-answering are not trained to properly understand the knowledge or…

Computation and Language · Computer Science 2024-05-30 Sanat Sharma , David Seunghyun Yoon , Franck Dernoncourt , Dewang Sultania , Karishma Bagga , Mengjiao Zhang , Trung Bui , Varun Kotte

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

Computation and Language · Computer Science 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

In recent years, the application of Large Language Models (LLMs) in healthcare has shown significant promise in improving the accessibility and dissemination of medical knowledge. This paper presents a detailed study of various LLMs trained…

Computation and Language · Computer Science 2024-08-09 Haoran Yu , Chang Yu , Zihan Wang , Dongxian Zou , Hao Qin

Recently, large language models such as GPT-2 have shown themselves to be extremely adept at text generation and have also been able to achieve high-quality results in many downstream NLP tasks such as text classification, sentiment…

Computation and Language · Computer Science 2019-11-22 Sam Witteveen , Martin Andrews

Clinical diagnosis is time-consuming, requiring intensive interactions between patients and medical professionals. While large language models (LLMs) could ease the pre-diagnostic workload, their limited domain knowledge hinders effective…

Computation and Language · Computer Science 2026-03-03 Liwen Sun , Xiang Yu , Ming Tan , Zhuohao Chen , Anqi Cheng , Ashutosh Joshi , Chenyan Xiong

Clinical Question Answering (CQA) plays a crucial role in medical decision-making, enabling physicians to extract relevant information from Electronic Medical Records (EMRs). While transformer-based models such as BERT, BioBERT, and…

Computation and Language · Computer Science 2025-04-24 Priyaranjan Pattnayak , Hitesh Laxmichand Patel , Amit Agarwal , Bhargava Kumar , Srikant Panda , Tejaswini Kumar

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

Healthcare systems continuously generate vast amounts of electronic health records (EHRs), commonly stored in the Fast Healthcare Interoperability Resources (FHIR) standard. Despite the wealth of information in these records, their…

Computation and Language · Computer Science 2025-01-24 Sara Kothari , Ayush Gupta

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Knowledge-aware question answering (KAQA) requires the model to answer questions over a knowledge base, which is essential for both open-domain QA and domain-specific QA, especially when language models alone cannot provide all the…

Computation and Language · Computer Science 2023-03-16 Qichen Ye , Bowen Cao , Nuo Chen , Weiyuan Xu , Yuexian Zou

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang