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Inspired by the success of deep learning techniques in the physical and chemical sciences, we apply a modification of an autoencoder type deep neural network to the task of dimension reduction of molecular dynamics data. We can show that…

Machine Learning · Statistics 2018-04-04 Christoph Wehmeyer , Frank Noé

A central problem in neuroscience is reconstructing neuronal circuits on the synapse level. Due to a wide range of scales in brain architecture such reconstruction requires imaging that is both high-resolution and high-throughput. Existing…

Computer Vision and Pattern Recognition · Computer Science 2012-10-03 Tao Hu , Juan Nunez-Iglesias , Shiv Vitaladevuni , Lou Scheffer , Shan Xu , Mehdi Bolorizadeh , Harald Hess , Richard Fetter , Dmitri Chklovskii

Protocol-dependent states in structural glasses can encode a disordered, yet retrievable memory. While training such materials is typically done via a global drive, such as external shear, in dense active matter the driving is instead local…

Soft Condensed Matter · Physics 2024-04-05 Elisabeth Agoritsas , Peter K. Morse

Random projections are able to perform dimension reduction efficiently for datasets with nonlinear low-dimensional structures. One well-known example is that random matrices embed sparse vectors into a low-dimensional subspace nearly…

Machine Learning · Computer Science 2019-01-11 Jian-Feng Cai , Dong Li , Jiaze Sun , Ke Wang

Memory for the past makes use of a record of what happened when---a function over past time. Time cells in the hippocampus and temporal context cells in the entorhinal cortex both code for events as a function of past time, but with very…

Neurons and Cognition · Quantitative Biology 2020-03-27 Marc W. Howard , Michael E. Hasselmo

Empirical evidence demonstrates that every region of the neocortex represents information using sparse activity patterns. This paper examines Sparse Distributed Representations (SDRs), the primary information representation strategy in…

Neurons and Cognition · Quantitative Biology 2015-03-26 Subutai Ahmad , Jeff Hawkins

Working memory - the ability to remember recent events as they recede continuously into the past - requires the ability to represent any stimulus at any time delay. This property requires neurons coding working memory to show mixed…

Neurons and Cognition · Quantitative Biology 2025-08-12 Aakash Sarkar , Chenyu Wang , Shangfu Zuo , Marc W. Howard

Declarative memory, the memory that can be "declared" in words or languages, is made up of two dissociated parts: episodic memory and semantic memory. This dissociation has its neuroanatomical basis episodic memory is mostly associated with…

Neurons and Cognition · Quantitative Biology 2026-02-10 Qi Zhang

A key aspect of text-to-image personalization methods is the manner in which the target concept is represented within the generative process. This choice greatly affects the visual fidelity, downstream editability, and disk space needed to…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Yuval Alaluf , Elad Richardson , Gal Metzer , Daniel Cohen-Or

Autoencoders exhibit impressive abilities to embed the data manifold into a low-dimensional latent space, making them a staple of representation learning methods. However, without explicit supervision, which is often unavailable, the…

Machine Learning · Computer Science 2023-01-12 Felix Leeb , Stefan Bauer , Michel Besserve , Bernhard Schölkopf

While deep learning surpasses human-level performance in narrow and specific vision tasks, it is fragile and over-confident in classification. For example, minor transformations in perspective, illumination, or object deformation in the…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Maryam Daniali , Edward Kim

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

In a wide variety of applications, humans interact with a complex environment by means of asynchronous stochastic discrete events in continuous time. Can we design online interventions that will help humans achieve certain goals in such…

Machine Learning · Computer Science 2018-11-07 Utkarsh Upadhyay , Abir De , Manuel Gomez-Rodriguez

Discussions of the hippocampus often focus on place cells, but many neurons are not place cells in any given environment. Here we describe the collective activity in such mixed populations, treating place and non-place cells on the same…

Neurons and Cognition · Quantitative Biology 2019-01-01 Leenoy Meshulam , Jeffrey L. Gauthier , Carlos D. Brody , David W. Tank , William Bialek

A spiking neuron ``computes'' by transforming a complex dynamical input into a train of action potentials, or spikes. The computation performed by the neuron can be formulated as dimensional reduction, or feature detection, followed by a…

Biological Physics · Physics 2007-05-23 Blaise Aguera y Arcas , Adrienne L. Fairhall , William Bialek

Visual localization techniques rely upon some underlying scene representation to localize against. These representations can be explicit such as 3D SFM map or implicit, such as a neural network that learns to encode the scene. The former…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Maxime Pietrantoni , Gabriela Csurka , Martin Humenberger , Torsten Sattler

Deep convolutional neural networks (CNNs) are becoming increasingly popular models to predict neural responses in visual cortex. However, contextual effects, which are prevalent in neural processing and in perception, are not explicitly…

Neurons and Cognition · Quantitative Biology 2018-12-27 Luis Gonzalo Sanchez Giraldo , Odelia Schwartz

This work is centred around the recently proposed product key memory structure \cite{large_memory}, implemented for a number of computer vision applications. The memory structure can be regarded as a simple computation primitive suitable to…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Rasul Karimov , Yury Malkov , Karim Iskakov , Victor Lempitsky

We propose a hierarchically structured reinforcement learning approach to address the challenges of planning for generating coherent multi-sentence stories for the visual storytelling task. Within our framework, the task of generating a…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Qiuyuan Huang , Zhe Gan , Asli Celikyilmaz , Dapeng Wu , Jianfeng Wang , Xiaodong He

Neurons in a micro-circuit connected by chemical synapses can have their connectivity affected by the prior activity of the cells. The number of synapses available for releasing neurotransmitter can be decreased by repetitive activation…

Neurons and Cognition · Quantitative Biology 2018-04-09 Elham Bayat Mokhtari , J. Josh Lawrence , Emily F Stone