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Recently, molecule generation using deep learning has been actively investigated in drug discovery. In this field, Transformer and VAE are widely used as powerful models, but they are rarely used in combination due to structural and…

Biomolecules · Quantitative Biology 2024-04-08 Yasuhiro Yoshikai , Tadahaya Mizuno , Shumpei Nemoto , Hiroyuki Kusuhara

Accurate particle shower simulation remains a critical computational bottleneck for high-energy physics. Traditional Monte Carlo methods, such as Geant4, are computationally prohibitive, while existing machine learning surrogates are tied…

Instrumentation and Detectors · Physics 2025-12-02 Frank Gaede , Gregor Kasieczka , Lorenzo Valente

The design of particle simulation methods for collisional plasma physics has always represented a challenge due to the unbounded total collisional cross section, which prevents a natural extension of the classical Direct Simulation Monte…

Numerical Analysis · Mathematics 2024-02-09 Andrea Medaglia , Lorenzo Pareschi , Mattia Zanella

Physics-informed neural networks (PINNs) have successfully addressed various computational physics problems based on partial differential equations (PDEs). However, while tackling issues related to irregularities like singularities and…

Machine Learning · Computer Science 2024-11-25 Hang Hu , Sidi Wu , Guoxiong Cai , Na Liu

In quantum many-body systems, measurements can induce qualitative new features, but their simulation is hindered by the exponential complexity involved in sampling the measurement results. We propose to use machine learning to assist the…

Quantum Physics · Physics 2024-12-03 Yuchen Zhu , Molei Tao , Yuebo Jin , Xie Chen

The Standard Model of particle physics makes it possible to simulate complete events for physics signatures and their backgrounds in high energy collisions. Knowledge of how the produced particles interact with the materials in a detector…

High Energy Physics - Phenomenology · Physics 2009-09-25 K. D. Lane , F. E. Paige , T. Skwarnicki , W. J. Womersley

The physics programs of current and future collider experiments necessitate the development of surrogate simulators for calorimeter showers. While much progress has been made in the development of generative models for this task, they have…

High Energy Physics - Experiment · Physics 2025-11-24 Thorsten Buss , Henry Day-Hall , Frank Gaede , Gregor Kasieczka , Katja Krüger , Anatolii Korol , Thomas Madlener , Peter McKeown

In this work, we introduce a novel method for Particle Identification (PID) within the scope of the ALICE experiment at the Large Hadron Collider at CERN. Identifying products of ultrarelativisitc collisions delivered by the LHC is one of…

Instrumentation and Detectors · Physics 2024-07-23 Miłosz Kasak , Kamil Deja , Maja Karwowska , Monika Jakubowska , Łukasz Graczykowski , Małgorzata Janik

In the recent years, high energy physics discoveries have been driven by the increasing of luminosity and/or detector granularity. This evolution gives access to bigger statistics and data samples, but can make it hard to process results…

High Energy Physics - Experiment · Physics 2025-02-07 Matthieu Melennec , Shamik Ghosh , Frédéric Magniette

We present a new publicly available dataset that contains simulated data of a novel calorimeter to be installed at the CERN Large Hadron Collider. This detector will have more than six-million channels with each channel capable of position,…

High Energy Physics - Experiment · Physics 2023-09-14 Roger Rusack , Bhargav Joshi , Alpana Alpana , Seema Sharma , Thomas Vadnais

In the wake of the intense effort made for the experimental CILEX project, numerical simulation cam- paigns have been carried out in order to finalize the design of the facility and to identify optimal laser and plasma parameters. These…

Computational Physics · Physics 2016-04-20 Arnaud Beck , Jacob Trier Frederiksen , Julien Dérouillat

One of the main goals in the study of hadronic interactions at LHC energies is the attempt to characterize the mechanisms involved in particle production in different regimes. The charged-particle multiplicity is one of the most interesting…

High Energy Physics - Experiment · Physics 2024-04-08 Alek Hutson

The CALICE collaboration is developing highly granular calorimeters for experiments at a future lepton collider primarily to establish technologies for particle flow event reconstruction. These technologies also find applications elsewhere,…

Instrumentation and Detectors · Physics 2017-06-28 Yong Liu

Diffusion probabilistic models have been shown to generate state-of-the-art results on several competitive image synthesis benchmarks but lack a low-dimensional, interpretable latent space, and are slow at generation. On the other hand,…

Machine Learning · Computer Science 2022-11-30 Kushagra Pandey , Avideep Mukherjee , Piyush Rai , Abhishek Kumar

The measurements performed by particle physics experiments must account for the imperfect response of the detectors used to observe the interactions. One approach, unfolding, statistically adjusts the experimental data for detector effects.…

High Energy Physics - Experiment · Physics 2025-04-02 Alexander Shmakov , Kevin Greif , Michael James Fenton , Aishik Ghosh , Pierre Baldi , Daniel Whiteson

Identifying molecules that exhibit some pre-specified properties is a difficult problem to solve. In the last few years, deep generative models have been used for molecule generation. Deep Graph Variational Autoencoders are among the most…

Machine Learning · Computer Science 2023-06-09 Davide Rigoni , Nicolò Navarin , Alessandro Sperduti

Computational Fluid Dynamics (CFD) plays a pivotal role in fluid mechanics, enabling precise simulations of fluid behavior through partial differential equations (PDEs). However, traditional CFD methods are resource-intensive, particularly…

Computational Engineering, Finance, and Science · Computer Science 2025-02-06 Tiffany Fan , Murray Cutforth , Marta D'Elia , Alexandre Cortiella , Alireza Doostan , Eric Darve

The Gamma Factory (GF) proposal \cite{Krasny:2015ffb} is motivated by the recognition of a largely untapped potential of the CERN accelerator complex to enable a new research programme at the intersection of particle, nuclear, atomic,…

Accelerator Physics · Physics 2026-05-07 Mieczyslaw Witold Krasny

Full detector simulation was among the largest CPU consumer in all CERN experiment software stacks for the first two runs of the Large Hadron Collider (LHC). In the early 2010's, the projections were that simulation demands would scale…

Predicting drop coalescence based on process parameters is crucial for experiment design in chemical engineering. However, predictive models can suffer from the lack of training data and more importantly, the label imbalance problem. In…

Computational Engineering, Finance, and Science · Computer Science 2023-05-02 Kewei Zhu , Sibo Cheng , Nina Kovalchuk , Mark Simmons , Yi-Ke Guo , Omar K. Matar , Rossella Arcucci