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Stimulated Raman scattering (SRS) microscopy is a powerful label-free imaging technique that probes the vibrational response of chemicals with high specificity and sensitivity. High-power, quantum-enhanced SRS microscopes have been recently…

We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique…

Wavefront shaping is a powerful method to refocus light through a scattering medium. Its application to large spectral bandwidths or multiple wavelengths refocusing for nonlinear bio-imaging in-depth is however limited by spectral…

Automated experiments in scanning transmission electron microscopy (STEM) require rapid image segmentation to optimize data representation for human interpretation, decision-making, site-selective spectroscopies, and atomic manipulation.…

Materials Science · Physics 2024-09-23 Kamyar Barakati , Utkarsh Pratiush , Austin C. Houston , Gerd Duscher , Sergei V. Kalinin

The synthesis of multiple narrow optical spectral lines, precisely and independently tuned across the near- to mid-infrared (IR) region, is a pivotal research area that enables selective and real-time detection of trace gas species within…

Optical spectroscopy is a fundamental tool in numerous areas of science and technology. Much effort has focused on miniaturizing spectrometers, but thus far at the cost of high spectral resolution and broad operating range. Here, we…

Raman transitions have a wide range of applications in atomic physics and have recently been proposed as a means for improving high-precision high-voltage measurements. Here, we present a theoretical analysis and a first experimental…

Atomic Physics · Physics 2025-12-04 Julien Spahn , Hendrik Bodnar , Kristian König , Wilfried Nörtershäuser

We propose and experimentally demonstrate a fiber spectrum analyzer based on a planar waveguide chip butt-coupled with an input fiber and aligned to a standard camera without any free-space optical elements. The chip consists of a…

Scanning probe microscopy (SPM) is traditionally based on very sharp tips, where the small size of the apex is critical for resolution. This paradigm is about to shift, since a novel generation of planar probes (color centers in diamond,…

Instrumentation and Detectors · Physics 2021-06-24 Stefan Ernst , Dominik M. Irber , Andreas M. Waeber , Georg Braunbeck , Friedemann Reinhard

Ovarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several…

There are several growing methods for graphene. In this study, the growth of graphene-like clusters on the SiC wafers is done by annealing the wafers in a vacuum evaporation system equipped with a heating source accessory. For evaluating…

Mesoscale and Nanoscale Physics · Physics 2021-05-31 Seyed Sajad Sadeghi , Hamidreza Simchi

Excited-state vibrational dynamics in molecules can be studied by an electronically off-resonant Raman process induced by a probe pulse with variable delay with respect to an actinic pulse. We establish the connection between several…

Chemical Physics · Physics 2013-09-27 Konstantin E. Dorfman , Benjamin P. Fingerhut , Shaul Mukamel

Spectro-microscopy is an experimental technique which can be used to observe spatial variations in chemical state and changes in chemical state over time or under experimental conditions. As a result it has broad applications across areas…

Medical Physics · Physics 2026-02-05 Maike Meier , Lorenzo Lazzarino , Boris Shustin , Hussam Al Daas , Paul Quinn

The rapid and accurate detection of biochemical compositions in fish is a crucial real-world task that facilitates optimal utilization and extraction of high-value products in the seafood industry. Raman spectroscopy provides a promising…

Multimode fibres are becoming increasingly attractive in optical endoscopy as they promise to enable unparalleled miniaturisation, spatial resolution and cost as compared to conventional fibre bundle-based counterpart. However, achieving…

Medical Physics · Physics 2024-06-05 Tianrui Zhao , Michelle T. Ma , Sebastien Ourselin , Tom Vercauteren , Wenfeng Xia

Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…

Signal Processing · Electrical Eng. & Systems 2023-07-18 Olivier Leblanc , Matthias Hofer , Siddharth Sivankutty , Hervé Rigneault , Laurent Jacques

Stimulated Raman scattering (SRS) in ultra-high-Q surface-tension-induced spherical and chip-based toroid microcavities is considered both theoretically and experimentally. These microcavities are fabricated from silica, exhibit small mode…

Optics · Physics 2007-05-23 Tobias J. Kippenberg , Sean M. Spillane , Bumki Min , Kerry J. Vahala

We demonstrate pixelation-free real-time widefield endoscopic imaging through an aperiodic multicore fiber (MCF) without any distal opto-mechanical elements or proximal scanners. Exploiting the memory effect in MCFs the images in our system…

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

The average Raman signal power obtained in a modulated optical trap is dependent on the Brownian motion - therefore hydrodynamic properties of the trapped particle. Hence, in addition to the molecular properties obtained from the Raman…

Optics · Physics 2023-11-27 Rohin Sharma , Anusa Thapa , Rijan Maharjan , Ashim Dhakal
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