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This work proposes $\mu$GUIDE: a general Bayesian framework to estimate posterior distributions of tissue microstructure parameters from any given biophysical model or MRI signal representation, with exemplar demonstration in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Maëliss Jallais , Marco Palombo

Knowledge of the noise distribution in diffusion MRI is the centerpiece to quantify uncertainties arising from the acquisition process. Accurate estimation beyond textbook distributions often requires information about the acquisition…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Samuel St-Jean , Alberto De Luca , Chantal M. W. Tax , Max A. Viergever , Alexander Leemans

Diffusion-based generative models (DBGMs) perturb data to a target noise distribution and reverse this process to generate samples. The choice of noising process, or inference diffusion process, affects both likelihoods and sample quality.…

Machine Learning · Computer Science 2023-03-06 Raghav Singhal , Mark Goldstein , Rajesh Ranganath

High spatio-angular resolution diffusion MRI (dMRI) has been shown to provide accurate identification of complex neuronal fiber configurations, albeit, at the cost of long acquisition times. We propose a method to recover intra-voxel fiber…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Marica Pesce , Audrey Repetti , Anna Auría , Alessandro Daducci , Jean-Philippe Thiran , Yves Wiaux

Accurate estimation of intravoxel incoherent motion (IVIM) parameters from diffusion-weighted MRI remains challenging due to the ill-posed nature of the inverse problem and high sensitivity to noise, particularly in the perfusion…

Fast and accurate waveform simulation is critical for understanding fiber channel characteristics, developing digital signal processing (DSP) technologies, optimizing optical network configurations, and advancing the optical fiber…

Signal Processing · Electrical Eng. & Systems 2025-11-04 Minghui Shi , Hang Yang , Zekun Niu , Chuyan Zeng , Junzhe Xiao , Yunfan Zhang , Mingzhe Chen , Weisheng Hu , Lilin Yi

Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Shishuai Wang , Hua Ma , Juan A. Hernandez-Tamames , Stefan Klein , Dirk H. J. Poot

Diffusion weighted MRI (dMRI) provides a non invasive virtual reconstruction of the brain's white matter structures through tractography. Analyzing dMRI measures along the trajectory of white matter bundles can provide a more specific…

Quantitative Methods · Quantitative Biology 2019-06-21 Samuel St-Jean , Maxime Chamberland , Max A. Viergever , Alexander Leemans

Computational image reconstruction algorithms generally produce a single image without any measure of uncertainty or confidence. Regularized Maximum Likelihood (RML) and feed-forward deep learning approaches for inverse problems typically…

Machine Learning · Computer Science 2020-12-18 He Sun , Katherine L. Bouman

We present a novel way to model diffusion magnetic resonance imaging (dMRI) datasets, that benefits from the structural coherence of the human brain while only using data from a single subject. Current methods model the dMRI signal in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Tom Hendriks , Anna Vilanova , Maxime Chamberland

It can be challenging to identify brain MRI anomalies using supervised deep-learning techniques due to anatomical heterogeneity and the requirement for pixel-level labeling. Unsupervised anomaly detection approaches provide an alternative…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Hasan Iqbal , Umar Khalid , Jing Hua , Chen Chen

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

Diffusion MRI (dMRI) is a critical non-invasive technique to estimate fiber orientation distribution (FOD) for characterizing white matter integrity. Estimating FOD from single-shell low angular resolution dMRI (LAR-FOD) is limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Hao Tang , Hanyu Liu , Alessandro Perelli , Xi Chen , Chao Li

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

We develop a general analytical and numerical framework for estimating intra- and extra-neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion, in each imaging voxel. By employing a set of rotational…

Biological Physics · Physics 2018-04-10 Dmitry S. Novikov , Jelle Veraart , Ileana O. Jelescu , Els Fieremans

Most existing MRI reconstruction methods perform tar-geted reconstruction of the entire MR image without tak-ing specific tissue regions into consideration. This may fail to emphasize the reconstruction accuracy on im-portant tissues for…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Yu Guan , Chuanming Yu , Shiyu Lu , Zhuoxu Cui , Dong Liang , Qiegen Liu

Diffusion Probabilistic Models (DPMs) have been recently utilized to deal with various blind image restoration (IR) tasks, where they have demonstrated outstanding performance in terms of perceptual quality. However, the task-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Magauiya Zhussip , Iaroslav Koshelev , Stamatis Lefkimmiatis

Brain cell structure and function reflect neurodevelopment, plasticity and ageing, and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to non-invasively…

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

Performing magnetic resonance imaging (MRI) reconstruction from under-sampled k-space data can accelerate the procedure to acquire MRI scans and reduce patients' discomfort. The reconstruction problem is usually formulated as a denoising…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Tianqi Xiang , Wenjun Yue , Yiqun Lin , Jiewen Yang , Zhenkun Wang , Xiaomeng Li