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"Is it possible to predict expression levels of different genes at a given spatial location in the routine histology image of a tumor section by modeling its stain absorption characteristics?" In this work, we propose a "stain-aware"…

Image and Video Processing · Electrical Eng. & Systems 2021-08-27 Muhammad Dawood , Kim Branson , Nasir M. Rajpoot , Fayyaz ul Amir Afsar Minhas

Low-Light Image Enhancement (LLIE) task tends to restore the details and visual information from corrupted low-light images. Most existing methods learn the mapping function between low/normal-light images by Deep Neural Networks (DNNs) on…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Qingsen Yan , Yixu Feng , Cheng Zhang , Pei Wang , Peng Wu , Wei Dong , Jinqiu Sun , Yanning Zhang

While generative adversarial networks (GANs) can successfully produce high-quality images, they can be challenging to control. Simplifying GAN-based image generation is critical for their adoption in graphic design and artistic work. This…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Mahmoud Afifi , Marcus A. Brubaker , Michael S. Brown

We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Ramin Nateghi , Fattaneh Pourakpour

Medical imaging technologies are generating increasingly large amounts of high-quality, information-dense data. Despite the progress, practical use of advanced imaging technologies for research and diagnosis remains limited by cost and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-24 Lucas Farndale , Robert Insall , Ke Yuan

Unsupervised and unpaired domain translation using generative adversarial neural networks, and more precisely CycleGAN, is state of the art for the stain translation of histopathology images. It often, however, suffers from the presence of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Nicolas Brieu , Felix J. Segerer , Ansh Kapil , Philipp Wortmann , Guenter Schmidt

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Jianxu Chen , Chukka Srinivas

Recent inversion methods have shown that real images can be inverted into StyleGAN's latent space and numerous edits can be achieved on those images thanks to the semantically rich feature representations of well-trained GAN models.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Ahmet Burak Yildirim , Hamza Pehlivan , Bahri Batuhan Bilecen , Aysegul Dundar

The difficulty of detecting mitosis and its similarity to non-mitosis objects has remained a challenge in computational pathology. The lack of publicly available data has added more complexity. Deep learning algorithms have shown potentials…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Seyed H. Mirjahanmardi , Samir Mitha , Salar Razavi , Susan Done , April Khademi

Masked image modelling (MIM) is a powerful self-supervised representation learning paradigm, whose potential has not been widely demonstrated in medical image analysis. In this work, we show the capacity of MIM to capture rich semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Piotr Wójcik , Hussein Naji , Adrian Simon , Reinhard Büttner , Katarzyna Bożek

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

Multiple instance learning (MIL) is the dominant framework for whole-slide image analysis in computational pathology, typically combining a frozen patch encoder, a projection layer, and a slide-level aggregator. While encoders and…

Quantitative Methods · Quantitative Biology 2026-05-19 Yucheng Xing , Pei Liu , Jingying Ma , Ruping Hong , Jiangdong Qiu , Tianyu Liu , Kai He , Ling Huang , Mengling Feng

The convolution neural nets (conv nets) have achieved a state-of-the-art performance in many applications of image and video processing. The most recent studies illustrate that the conv nets are fragile in terms of recognition accuracy to…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Sergey Tarasenko , Fumihiko Takahashi

We present an innovative method for rapidly segmenting hematoxylin and eosin (H&E)-stained tissue in whole-slide images (WSIs) that eliminates a wide range of undesirable artefacts such as pen marks and scanning artefacts. Our method…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 B. A. Schreiber , J. Denholm , F. Jaeckle , M. J. Arends , K. M. Branson , C. -B. Schönlieb , E. J. Soilleux

Recent studies shows that the majority of existing deep steganalysis models have a large amount of redundancy, which leads to a huge waste of storage and computing resources. The existing model compression method cannot flexibly compress…

Computer Vision and Pattern Recognition · Computer Science 2022-06-14 Shunquan Tan , Qiushi Li , Laiyuan Li , Bin Li , Jiwu Huang

Photon Absorption Remote Sensing (PARS) enables label-free imaging of subcellular morphology by observing biomolecule specific absorption interactions. Coupled with deep-learning, PARS produces label-free virtual Hematoxylin and Eosin (H&E)…

The automated analysis of medical images is currently limited by technical and biological noise and bias. The same source tissue can be represented by vastly different images if the image acquisition or processing protocols vary. For an…

Image inpainting is an important task in computer vision. As admirable methods are presented, the inpainted image is getting closer to reality. However, the result is still not good enough in the reconstructed texture and structure based on…

Image and Video Processing · Electrical Eng. & Systems 2023-08-25 Tsung-Jung Liu , Bo-Wei Chen , Kuan-Hsien Liu

Immunohistochemical (IHC) staining highlights the molecular information critical to diagnostics in tissue samples. However, compared to H&E staining, IHC staining can be much more expensive in terms of both labor and the laboratory…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Fangda Li , Zhiqiang Hu , Wen Chen , Avinash Kak

Due to the high potential for abuse of GenAI systems, the task of detecting synthetic images has recently become of great interest to the research community. Unfortunately, existing image-space detectors quickly become obsolete as new…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 George Cazenavette , Avneesh Sud , Thomas Leung , Ben Usman