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Semiflexible polymers are ubiquitous in natural and artificial systems, where their intermediate rigidity gives rise to rich structural and dynamical behavior. Confinement plays a central role in these behaviors, as spatial restrictions can…

Soft Condensed Matter · Physics 2026-03-31 Nasir Amiri , Jonathan P. Singer , Xin Yong

We investigate the force generation by polymerizing bundles of filaments, which form because of short-range attractive filament interactions. We show that bundles can generate forces by a zipping mechanism, which is not limited by buckling…

Soft Condensed Matter · Physics 2012-05-02 Torsten Kuehne , Reinhard Lipowsky , Jan Kierfeld

Soft matter systems are common in nature and make up nearly all the essential components necessary for life, from cells to the organelles within those cells. The ability of these soft materials to deform is crucial for the proper…

Soft Condensed Matter · Physics 2025-12-02 Padmanabha Bose , Smarajit Karmakar

Frontal polymerization is a promising energy-saving method for rapid fabrication of polymer components with good mechanical properties. In these systems, a small energy input is sufficient to convert monomers, from a liquid or soft solid…

Soft Condensed Matter · Physics 2023-10-04 Xuanhe Li , Tal Cohen

Soft colloids allow to explore high density states well beyond random close packing. An important open question is whether softness controls the dynamics under these dense conditions. While experimental works reported conflicting results,…

Soft Condensed Matter · Physics 2021-06-08 Nicoletta Gnan , Emanuela Zaccarelli

We use numerical simulations to show how noninteracting hard particles binding to a deformable elastic shell may self-assemble into a variety of linear patterns. This is a result of the nontrivial elastic response to deformations of shells.…

Soft Condensed Matter · Physics 2011-02-25 Andela Šarić , Angelo Cacciuto

To study the compressional forces exerted by a bundle of living stiff filaments pressing on a surface, akin to the case of an actin bundle in filopodia structures, we have performed particulate Molecular Dynamics simulations of a grafted…

Soft Condensed Matter · Physics 2015-06-17 Sanoop Ramachandran , Jean-Paul Ryckaert

Limited-valency colloidal particles can self-assemble into polymeric structures analogous to molecules. While their structural equilibrium properties have attracted wide attention, insight into their dynamics has proven challenging. Here,…

Soft Condensed Matter · Physics 2021-09-08 Simon Stuij , Joep Rouwhorst , Hannah Jonas , Nicola Ruffino , Zhe Gong , Stefanno Sacanna , Peter Bolhuis , Peter Schall

We systematically explore the self-assembly of semi-flexible polymers in deformable spherical confinement across a wide regime of chain stiffness, contour lengths and packing fractions by means of coarse-grained molecular dynamics…

Soft Condensed Matter · Physics 2021-07-12 Maxime M. C. Tortora , Daniel Jost

Space-saving design is a requirement that is encountered in biological systems and the development of modern technological devices alike. Many living organisms dynamically pack their polymer chains, filaments or membranes inside of…

Soft Condensed Matter · Physics 2014-07-18 Roman Vetter , Falk K. Wittel , Hans J. Herrmann

Hollow microgels are elastic polymer shells easily realizable in experiments. Recent works have shown the emergence of buckling events in dilute hollow microgels under the effect of an added osmotic pressure. Here, we perform large-scale…

Soft Condensed Matter · Physics 2026-01-19 Leah Rank , Emanuela Zaccarelli

Biological systems exploit self-assembly to create complex structures whose arrangements are finely controlled from molecular to mesoscopic level. Herein we report an example of using fully synthetic systems that mimic two levels of…

Animal cells form contractile structures to promote various functions, from cell motility to cell division. Force generation in these structures is often due to molecular motors such as myosin that require polar substrates for their…

Biological Physics · Physics 2020-11-18 Sihan Chen , Tomer Markovich , F. C. MacKintosh

Generation of mechanical force regulated by external electric field is studied both theoretically and by molecular dynamics (MD) simulations. The force arises in deformable bodies linked to the free end of a grafted polyelectrolyte chain…

Statistical Mechanics · Physics 2014-11-11 Christian Seidel , Yury A. Budkov , Nikolay V. Brilliantov

Contractility in animal cells is often generated by molecular motors such as myosin, which require polar substrates for their function. Motivated by recent experimental evidence of motor-independent contractility, we propose a robust…

Soft Condensed Matter · Physics 2022-05-04 Sihan Chen , Tomer Markovich , Fred C. MacKintosh

Using field theoretic approach, we study equilibrium shape deformation of a vesicle induced by the presence of enclosed flexible polymers, which is a simple model of drug delivery system or endocytosis. To evaluate the total free energy of…

Soft Condensed Matter · Physics 2015-05-20 Yutaka Oya , Katsuhiko Sato , Toshihiro Kawakatsu

The importance of molecular-scale forces in sculpting biological form and function has been acknowledged for more than a century. Accounting for forces in biology is a problem that lies at the intersection of soft condensed matter physics,…

Soft Condensed Matter · Physics 2025-12-10 K. Vijay Kumar , Mandar M. Inamdar , Pramod A. Pullarkat , Gautam I. Menon

One of the most unique physical features of cell adhesion to external surfaces is the active generation of mechanical force at the cell-material interface. This includes pulling forces generated by contractile polymer bundles and networks,…

Cell Behavior · Quantitative Biology 2013-09-12 Ulrich S. Schwarz , Samuel S. Safran

The process of force generation by the growth of biopolymers is simulated via a Langevin-dynamics approach. The interaction forces are taken to have simple forms that favor the growth of straight fibers from solution. The force-velocity…

Biological Physics · Physics 2009-11-06 A. E. Carlsson

We study theoretically and by means of molecular dynamics (MD) simulations the generation of mechanical force by grafted polyelectrolytes in an external electric field, which favors its adsorption on the grafting plane. The force arises in…

Soft Condensed Matter · Physics 2016-03-18 N. V. Brilliantov , Yu. A. Budkov , C. Seidel
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