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The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Recent advancements in AI applications to healthcare have shown incredible promise in surpassing human performance in diagnosis and disease prognosis. With the increasing complexity of AI models, however, concerns regarding their opacity,…

Machine Learning · Computer Science 2023-08-17 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Explainable Artificial Intelligence (XAI) has re-emerged in response to the development of modern AI and ML systems. These systems are complex and sometimes biased, but they nevertheless make decisions that impact our lives. XAI systems are…

Artificial Intelligence · Computer Science 2021-02-10 Shane T. Mueller , Elizabeth S. Veinott , Robert R. Hoffman , Gary Klein , Lamia Alam , Tauseef Mamun , William J. Clancey

To facilitate the widespread acceptance of AI systems guiding decision-making in real-world applications, it is key that solutions comprise trustworthy, integrated human-AI systems. Not only in safety-critical applications such as…

Artificial Intelligence · Computer Science 2020-01-16 Florian Buettner , John Piorkowski , Ian McCulloh , Ulli Waltinger

Human-in-the-loop validation is essential in safety-critical clinical AI, yet the transition between initial model inference and expert correction is rarely analyzed as a structured signal. We introduce a diagnostic alignment framework in…

Artificial Intelligence · Computer Science 2026-02-27 Dimitrios P. Panagoulias , Evangelia-Aikaterini Tsichrintzi , Georgios Savvidis , Evridiki Tsoureli-Nikita

Activation steering methods in large language models (LLMs) have emerged as an effective way to perform targeted updates to enhance generated language without requiring large amounts of adaptation data. We ask whether the features…

Computation and Language · Computer Science 2025-11-05 Masha Fedzechkina , Eleonora Gualdoni , Sinead Williamson , Katherine Metcalf , Skyler Seto , Barry-John Theobald

Autonomous vehicles often make complex decisions via machine learning-based predictive models applied to collected sensor data. While this combination of methods provides a foundation for real-time actions, self-driving behavior primarily…

Robotics · Computer Science 2024-04-12 Shahin Atakishiyev , Mohammad Salameh , Randy Goebel

Interpretability has become an essential topic for artificial intelligence in some high-risk domains such as healthcare, bank and security. For commonly-used tabular data, traditional methods trained end-to-end machine learning models with…

Artificial Intelligence · Computer Science 2022-08-18 Haixiao Chi , Dawei Wang , Gaojie Cui , Feng Mao , Beishui Liao

With the rise of AI systems in real-world applications comes the need for reliable and trustworthy AI. An essential aspect of this are explainable AI systems. However, there is no agreed standard on how explainable AI systems should be…

Artificial Intelligence · Computer Science 2022-07-04 Sascha Saralajew , Ammar Shaker , Zhao Xu , Kiril Gashteovski , Bhushan Kotnis , Wiem Ben Rim , Jürgen Quittek , Carolin Lawrence

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Using machine learning in high-stakes applications often requires predictions to be accompanied by explanations comprehensible to the domain user, who has ultimate responsibility for decisions and outcomes. Recently, a new framework for…

As AI-powered systems increasingly mediate consequential decision-making, their explainability is critical for end-users to take informed and accountable actions. Explanations in human-human interactions are socially-situated. AI systems…

Human-Computer Interaction · Computer Science 2021-01-14 Upol Ehsan , Q. Vera Liao , Michael Muller , Mark O. Riedl , Justin D. Weisz

Explainable AI (XAI) can greatly enhance user trust and satisfaction in AI-assisted decision-making processes. Recent findings suggest that a single explainer may not meet the diverse needs of multiple users in an AI system; indeed, even…

Explainability has been a goal for Artificial Intelligence (AI) systems since their conception, with the need for explainability growing as more complex AI models are increasingly used in critical, high-stakes settings such as healthcare.…

Artificial Intelligence · Computer Science 2020-10-06 Shruthi Chari , Oshani Seneviratne , Daniel M. Gruen , Morgan A. Foreman , Amar K. Das , Deborah L. McGuinness

Artificial intelligence (AI) copilots are increasingly integrated into enterprise cybersecurity platforms to assist analysts in threat detection, triage, and remediation. However, the effectiveness of these systems depends not only on the…

Human-Computer Interaction · Computer Science 2026-02-02 Mona Rajhans

In recent years, Explainable AI (XAI) methods have facilitated profound validation and knowledge extraction from ML models. While extensively studied for classification, few XAI solutions have addressed the challenges specific to regression…

Machine Learning · Computer Science 2025-07-21 Simon Letzgus , Klaus-Robert Müller , Grégoire Montavon

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Predictive models are increasingly used to make various consequential decisions in high-stakes domains such as healthcare, finance, and policy. It becomes critical to ensure that these models make accurate predictions, are robust to shifts…

Machine Learning · Computer Science 2022-09-22 Murtuza N Shergadwala , Himabindu Lakkaraju , Krishnaram Kenthapadi

In complex inferential tasks like question answering, machine learning models must confront two challenges: the need to implement a compositional reasoning process, and, in many applications, the need for this reasoning process to be…

Computer Vision and Pattern Recognition · Computer Science 2019-03-08 Ronghang Hu , Jacob Andreas , Trevor Darrell , Kate Saenko

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui
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