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Large language models (LLMs) have significantly advanced natural language processing tasks, yet they are susceptible to generating inaccurate or unreliable responses, a phenomenon known as hallucination. In critical domains such as health…

Computation and Language · Computer Science 2024-09-20 Sumera Anjum , Hanzhi Zhang , Wenjun Zhou , Eun Jin Paek , Xiaopeng Zhao , Yunhe Feng

We present an advanced approach to medical question-answering (QA) services, using fine-tuned Large Language Models (LLMs) to improve the accuracy and reliability of healthcare information. Our study focuses on optimizing models like…

Computation and Language · Computer Science 2024-10-22 Ali Anaissi , Ali Braytee , Junaid Akram

Hallucination in large language models (LLMs) during long-form generation remains difficult to address under existing reinforcement learning from human feedback (RLHF) frameworks, as their preference rewards often overlook the model's own…

Computation and Language · Computer Science 2026-05-08 Junliang Li , Yucheng Wang , Yan Chen , Yu Ran , Ruiqing Zhang , Jing Liu , Hua Wu , Haifeng Wang

Large language models (LLMs) are rapidly transitioning into medical clinical use, yet their reliability under realistic, multi-turn interactions remains poorly understood. Existing evaluation frameworks typically assess single-turn question…

Computation and Language · Computer Science 2025-10-15 Blazej Manczak , Eric Lin , Francisco Eiras , James O' Neill , Vaikkunth Mugunthan

Long-Context Question Answering (LCQA), a challenging task, aims to reason over long-context documents to yield accurate answers to questions. Existing long-context Large Language Models (LLMs) for LCQA often struggle with the "lost in the…

Computation and Language · Computer Science 2024-11-04 Qingfei Zhao , Ruobing Wang , Yukuo Cen , Daren Zha , Shicheng Tan , Yuxiao Dong , Jie Tang

Biomedical question answering often requires decisions from retrieved literature whose relevance, quality, and support for candidate answers are uneven. Most retrieval-augmented large language model (LLM) methods feed this literature to the…

Computation and Language · Computer Science 2026-05-19 Chang Zong , Hao Ning , Siliang Tang , Jie Huang , Jian Wan

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

The Mental Health Question Answer (MHQA) task requires the seeker and supporter to complete the support process in one-turn dialogue. Given the richness of help-seeker posts, supporters must thoroughly understand the content and provide…

Computation and Language · Computer Science 2025-01-28 Qi Chen , Dexi Liu

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Objective: To enhance the efficiency and accuracy of information retrieval from pharmacovigilance (PV) databases by employing Large Language Models (LLMs) to convert natural language queries (NLQs) into Structured Query Language (SQL)…

Artificial Intelligence · Computer Science 2025-04-18 Jeffery L. Painter , Venkateswara Rao Chalamalasetti , Raymond Kassekert , Andrew Bate

This study delves into the capabilities and limitations of Large Language Models (LLMs) in the challenging domain of conditional question-answering. Utilizing the Conditional Question Answering (CQA) dataset and focusing on generative…

Computation and Language · Computer Science 2023-12-05 Syed-Amad Hussain , Parag Pravin Dakle , SaiKrishna Rallabandi , Preethi Raghavan

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

Large language models (LLMs) hold great promise for assisting clinical interviews due to their fluent interactive capabilities and extensive medical knowledge. However, the lack of high-quality interview dialogue data and widely accepted…

Computation and Language · Computer Science 2025-04-15 Jing Chen , Zhihua Wei , Wei Zhang , Yingying Hu , Qiong Zhang

The advent of Large Language Models (LLMs) has significantly transformed the AI landscape, enhancing machine learning and AI capabilities. Factuality issue is a critical concern for LLMs, as they may generate factually incorrect responses.…

Computation and Language · Computer Science 2024-04-02 Xiaoze Liu , Feijie Wu , Tianyang Xu , Zhuo Chen , Yichi Zhang , Xiaoqian Wang , Jing Gao

Reducing hallucination of Large Language Models (LLMs) is imperative for use in the sciences, where reliability and reproducibility are crucial. However, LLMs inherently lack long-term memory, making it a nontrivial, ad hoc, and inevitably…

Computation and Language · Computer Science 2024-10-11 Yuan Chiang , Elvis Hsieh , Chia-Hong Chou , Janosh Riebesell