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To date, most dendritic studies have predominantly focused on the apical zone of pyramidal two-point neurons (TPNs) receiving only feedback (FB) connections from higher perceptual layers and using them for learning. Recent cellular…
Neural operators have been applied in various scientific fields, such as solving parametric partial differential equations, dynamical systems with control, and inverse problems. However, challenges arise when dealing with input functions…
How extracellular electric fields, as generated endogenously or through transcranial brain stimulation, affect the dynamics of large neuronal populations is of great interest but not well understood. To study the collective dynamics of…
Dendritic computation endows biological neurons with rich nonlinear integration and high representational capacity, yet it is largely missing in existing deep spiking neural networks (SNNs). Although detailed multi-compartment models can…
We propose a formal mathematical model for sparse representations and active dendrites in neocortex. Our model is inspired by recent experimental findings on active dendritic processing and NMDA spikes in pyramidal neurons. These…
Unsupervised semantic segmentation is a long-standing challenge in computer vision with great significance. Spectral clustering is a theoretically grounded solution to it where the spectral embeddings for pixels are computed to construct…
We assume that, within the dense clusters of neurons that can be found in nuclei, cells may interconnect via soma-to-soma interactions, in addition to conventional synaptic connections. We illustrate this idea with a multi-layer…
Understanding how biological constraints shape neural computation is a central goal of computational neuroscience. Spatially embedded recurrent neural networks provide a promising avenue to study how modelled constraints shape the combined…
Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep…
Simple spike synchrony between Purkinje cells projecting to a common neuron in the deep cerebellar nucleus is emerging as an important factor in the encoding of output information from cerebellar cortex. Stochastic synchronization is a…
Functional properties of neurons are strongly coupled with their morphology. Changes in neuronal activity alter morphological characteristics of dendritic spines. First step towards understanding the structure-function relationship is to…
Spiking neurons can perform spatiotemporal feature detection by nonlinear synaptic and dendritic integration of presynaptic spike patterns. Multicompartment models of non-linear dendrites and related neuromorphic circuit designs enable…
While the human brain efficiently adapts to new tasks from a continuous stream of information, neural network models struggle to learn from sequential information without catastrophically forgetting previously learned tasks. This limitation…
Heterogeneity of neural attributes has recently gained a lot of attention and is increasing recognized as a crucial feature in neural processing. Despite its importance, this physiological feature has traditionally been neglected in…
Neurons are spatially extended cells; different parts of a neuron have specific voltage dynamics. Important types of neurons even generate different spikes in different parts of the cell. Neurons' inputs are also often spatially…
The brain is a highly efficient system evolved to achieve high performance with limited resources. We propose that dendrites make information processing and storage in the brain more efficient through the segregation of inputs and their…
Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…
Dendrites are extensions to the neuronal cell body in the brain which are posited in several functions ranging from electrical and chemical compartmentalization to coincident detection. Dendrites vary across cell types but one common…
Neocortical pyramidal neurons have many dendrites, and such dendrites are capable of, in isolation of one-another, generating a neuronal spike. It is also now understood that there is a large amount of dendritic growth during the first…
Neurons are thought of as the building blocks of excitable brain tissue. However, at the single neuron level, the neuronal membrane, the dendritic arbor and the axonal projections can also be considered an extended active medium. Active…