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Objective: ML-based clinical risk prediction models are increasingly used to support decision-making in healthcare. While class-imbalance correction techniques are commonly applied to improve model performance in settings with rare…

The traditional activity of model selection aims at discovering a single model superior to other candidate models. In the presence of pronounced noise, however, multiple models are often found to explain the same data equally well. To…

Methodology · Statistics 2017-09-14 Chao Zheng , Davide Ferrari , Yuhong Yang

A generalization of the classical concordance correlation coefficient (CCC) is considered under a three-level design where multiple raters rate every subject over time, and each rater is rating every subject multiple times at each measuring…

Methodology · Statistics 2025-04-15 Soumya Sahu , Thomas Mathew , Dulal K. Bhaumik

As machine learning (ML) systems increasingly permeate high-stakes settings such as healthcare, transportation, military, and national security, concerns regarding their reliability have emerged. Despite notable progress, the performance of…

Machine Learning · Computer Science 2023-08-01 Anthony Corso , David Karamadian , Romeo Valentin , Mary Cooper , Mykel J. Kochenderfer

The performance of a binary classifier is described by a confusion matrix with four entries: the number of true positives (TP), true negatives (TN), false positives (FP), and false negatives (FN). The Matthews Correlation Coefficient (MCC),…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Jon Crall

The importance of uncertainty quantification is increasingly recognized in the diverse field of machine learning. Accurately assessing model prediction uncertainty can help provide deeper understanding and confidence for researchers and…

Machine Learning · Computer Science 2024-12-03 Tianyi Chen , Yingzhou Lu , Nan Hao , Yuanyuan Zhang , Capucine Van Rechem , Jintai Chen , Tianfan Fu

Class imbalance poses a significant challenge to supervised classification, particularly in critical domains like medical diagnostics and anomaly detection where minority class instances are rare. While numerous studies have explored…

Machine Learning · Computer Science 2025-09-10 Ali Nawaz , Amir Ahmad , Shehroz S. Khan

Where performance comparison of healthcare providers is of interest, characteristics of both patients and the health condition of interest must be balanced across providers for a fair comparison. This is unlikely to be feasible within…

Methodology · Statistics 2019-09-04 Wendy J. Harrison , Paul D. Baxter , Mark S. Gilthorpe

In the deployment of large language models (LLMs), accurate confidence estimation is critical for assessing the credibility of model predictions. However, existing methods often fail to overcome the issue of overconfidence on incorrect…

Computation and Language · Computer Science 2024-02-20 Pei Wang , Yejie Wang , Muxi Diao , Keqing He , Guanting Dong , Weiran Xu

MCMC methods are used in Bayesian statistics not only to sample from posterior distributions but also to estimate expectations. Underlying functions are most often defined on a continuous state space and can be unbounded. We consider a…

Methodology · Statistics 2009-07-29 Krzysztof Latuszynski , Blazej Miasojedow , Wojciech Niemiro

Measuring treatment effects in observational studies is challenging because of confounding bias. Confounding occurs when a variable affects both the treatment and the outcome. Traditional methods such as propensity score matching estimate…

Methodology · Statistics 2021-12-23 Bevan I. Smith , Charles Chimedza

Quantitative characterizations and estimations of uncertainty are of fundamental importance in optimization and decision-making processes. Herein, we propose intuitive scores, which we call certainty and doubt, that can be used in both a…

Probability forecasts for binary outcomes, often referred to as probabilistic classifiers or confidence scores, are ubiquitous in science and society, and methods for evaluating and comparing them are in great demand. We propose and study a…

Methodology · Statistics 2023-01-27 Timo Dimitriadis , Tilmann Gneiting , Alexander I. Jordan , Peter Vogel

The maximal correlation coefficient is a well-established generalization of the Pearson correlation coefficient for measuring non-linear dependence between random variables. It is appealing from a theoretical standpoint, satisfying…

Information Theory · Computer Science 2019-06-04 Elad Domanovitz , Uri Erez

Several neural-based metrics have been recently proposed to evaluate machine translation quality. However, all of them resort to point estimates, which provide limited information at segment level. This is made worse as they are trained on…

Computation and Language · Computer Science 2022-03-28 Taisiya Glushkova , Chrysoula Zerva , Ricardo Rei , André F. T. Martins

Machine learning (ML) is transforming healthcare, but safe clinical decisions demand reliable uncertainty estimates that standard ML models fail to provide. Conformal prediction (CP) is a popular tool that allows users to turn heuristic…

Machine Learning · Computer Science 2025-12-18 Klaus-Rudolf Kladny , Bernhard Schölkopf , Lisa Koch , Christian F. Baumgartner , Michael Muehlebach

Model-Predictive Control (MPC) is a powerful tool for controlling complex, real-world systems that uses a model to make predictions about future behavior. For each state encountered, MPC solves an online optimization problem to choose a…

Machine Learning · Computer Science 2021-04-15 Mohak Bhardwaj , Sanjiban Choudhury , Byron Boots

Context: Software engineering researchers have undertaken many experiments investigating the potential of software defect prediction algorithms. Unfortunately, some widely used performance metrics are known to be problematic, most notably…

Software Engineering · Computer Science 2021-06-23 Jingxiu Yao , Martin Shepperd

Model Predictive Control (MPC) is a powerful framework for constrained control, but its performance and safety can be severely degraded when the prediction model is learned online and thus remains uncertain. In this work, we develop a…

Optimization and Control · Mathematics 2025-12-01 Yingke Li , Yifan Lin , Enlu Zhou , Fumin Zhang

Deep neural networks (DNNs) have made great strides in pushing the state-of-the-art in several challenging domains. Recent studies reveal that they are prone to making overconfident predictions. This greatly reduces the overall trust in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Vinith Kugathasan , Muhammad Haris Khan