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People experiencing severe distress increasingly use Large Language Model (LLM) chatbots as mental health support tools. Discussions on social media have described how engagements were lifesaving for some, but evidence suggests that…

Human-Computer Interaction · Computer Science 2025-05-12 Inhwa Song , Sachin R. Pendse , Neha Kumar , Munmun De Choudhury

Large Language Models (LLMs) are increasingly utilized for mental health support; however, current safety benchmarks often fail to detect the complex, longitudinal risks inherent in therapeutic dialogue. We introduce an evaluation framework…

Computation and Language · Computer Science 2026-03-06 Ian Steenstra , Paola Pedrelli , Weiyan Shi , Stacy Marsella , Timothy W. Bickmore

Large language models (LLMs) have attracted significant attention for potential applications in digital health, while their application in mental health is subject to ongoing debate. This systematic review aims to evaluate the usage of LLMs…

Computers and Society · Computer Science 2024-08-14 Zhijun Guo , Alvina Lai , Johan Hilge Thygesen , Joseph Farrington , Thomas Keen , Kezhi Li

The integration of Large Language Models (LLMs) into the healthcare domain has the potential to significantly enhance patient care and support through the development of empathetic, patient-facing chatbots. This study investigates an…

Computation and Language · Computer Science 2024-05-28 Man Luo , Christopher J. Warren , Lu Cheng , Haidar M. Abdul-Muhsin , Imon Banerjee

LGBTQ+ individuals are increasingly turning to chatbots powered by large language models (LLMs) to meet their mental health needs. However, little research has explored whether these chatbots can adequately and safely provide tailored…

Human-Computer Interaction · Computer Science 2024-02-15 Zilin Ma , Yiyang Mei , Yinru Long , Zhaoyuan Su , Krzysztof Z. Gajos

Access to mental health support remains limited, particularly in marginalized communities where structural and cultural barriers hinder timely care. This paper explores the potential of AI-enabled chatbots as a scalable solution, focusing…

Computers and Society · Computer Science 2024-10-07 Rawan AlMakinah , Andrea Norcini-Pala , Lindsey Disney , M. Abdullah Canbaz

The past decade has been transformative for mental health research and practice. The ability to harness large repositories of data, whether from electronic health records (EHR), mobile devices, or social media, has revealed a potential for…

Computation and Language · Computer Science 2023-11-28 Munmun De Choudhury , Sachin R. Pendse , Neha Kumar

Large Language Models (LLMs) are transforming mental health care by enhancing accessibility, personalization, and efficiency in therapeutic interventions. These AI-driven tools empower mental health professionals with real-time support,…

Computers and Society · Computer Science 2025-01-22 Hari Mohan Pandey

Large Language Models (LLMs) have demonstrated remarkable performance across various information-seeking and reasoning tasks. These computational systems drive state-of-the-art dialogue systems, such as ChatGPT and Bard. They also carry…

Computation and Language · Computer Science 2023-10-13 Siyuan Brandon Loh , Aravind Sesagiri Raamkumar

Large language models (LLMs) chatbots like ChatGPT are increasingly used for mental health support. They offer accessible, therapeutic support but also raise concerns about misinformation, over-reliance, and risks in high-stakes contexts of…

Computers and Society · Computer Science 2025-12-09 Lingyao Li , Xiaoshan Huang , Renkai Ma , Ben Zefeng Zhang , Haolun Wu , Fan Yang , Chen Chen

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

Recent advancements in large language models (LLMs) promise to expand mental health interventions by emulating therapeutic techniques, potentially easing barriers to care. Yet there is a lack of real-world empirical evidence evaluating the…

Human-Computer Interaction · Computer Science 2025-01-28 Yinzhou Wang , Yimeng Wang , Ye Xiao , Liabette Escamilla , Bianca Augustine , Kelly Crace , Gang Zhou , Yixuan Zhang

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Computation and Language · Computer Science 2024-04-23 Zhe He , Balu Bhasuran , Qiao Jin , Shubo Tian , Karim Hanna , Cindy Shavor , Lisbeth Garcia Arguello , Patrick Murray , Zhiyong Lu

We investigate the role of large language models (LLMs) in supporting mental health by analyzing Reddit posts and comments about mental health conversations with ChatGPT. Our findings reveal that users value ChatGPT as a safe,…

Human-Computer Interaction · Computer Science 2025-10-28 Kyuha Jung , Gyuho Lee , Yuanhui Huang , Yunan Chen

The emergence of generative AI chatbots such as ChatGPT has prompted growing public and academic interest in their role as informal mental health support tools. While early rule-based systems have been around for several years, large…

Computation and Language · Computer Science 2025-04-18 Anna-Carolina Haensch

The global mental health crisis is looming with a rapid increase in mental disorders, limited resources, and the social stigma of seeking treatment. As the field of artificial intelligence (AI) has witnessed significant advancements in…

Computation and Language · Computer Science 2023-11-27 Neo Christopher Chung , George Dyer , Lennart Brocki

LGBTQ+ community face disproportionate mental health challenges, including higher rates of depression, anxiety, and suicidal ideation. Research has shown that LGBTQ+ people have been using large language model-based chatbots, such as…

Human-Computer Interaction · Computer Science 2024-05-09 Yinru Long , Zilin Ma , Yiyang Mei , Zhaoyuan Su

Large language model-powered chatbots have transformed how people seek information, especially in high-stakes contexts like mental health. Despite their support capabilities, safe detection and response to crises such as suicidal ideation…

Computation and Language · Computer Science 2026-04-09 Adrian Arnaiz-Rodriguez , Miguel Baidal , Erik Derner , Jenn Layton Annable , Mark Ball , Mark Ince , Elvira Perez Vallejos , Nuria Oliver

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

Large language models (LLMs) have offered new opportunities for emotional support, and recent work has shown that they can produce empathic responses to people in distress. However, long-term mental well-being requires emotional…

Computation and Language · Computer Science 2024-08-09 Hongli Zhan , Allen Zheng , Yoon Kyung Lee , Jina Suh , Junyi Jessy Li , Desmond C. Ong
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