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Molecular optimization is a fundamental goal in the chemical sciences and is of central interest to drug and material design. In recent years, significant progress has been made in solving challenging problems across various aspects of…

Computational Engineering, Finance, and Science · Computer Science 2022-10-11 Wenhao Gao , Tianfan Fu , Jimeng Sun , Connor W. Coley

Model merging combines independent solutions with different capabilities into a single one while maintaining the same inference cost. Two popular approaches are linear interpolation, which simply averages multiple model weights, and task…

Machine Learning · Computer Science 2026-04-22 Chenxiang Zhang , Alexander Theus , Damien Teney , Antonio Orvieto , Jun Pang , Sjouke Mauw

Cumulative probability models (CPMs) are a robust alternative to linear models for continuous outcomes. However, they are not feasible for very large datasets due to elevated running time and memory usage, which depend on the sample size,…

Computation · Statistics 2022-07-15 Chun Li , Guo Chen , Bryan E. Shepherd

The field of machine learning has seen tremendous progress in recent years, with deep learning models delivering exceptional performance across a range of tasks. However, these models often come at the cost of interpretability, as they…

Machine Learning · Computer Science 2024-01-08 Shun Liu

The mean dimension of a black box function of $d$ variables is a convenient way to summarize the extent to which it is dominated by high or low order interactions. It is expressed in terms of $2^d-1$ variance components but it can be…

Methodology · Statistics 2021-01-01 Christopher Hoyt , Art B. Owen

A mathematical framework for modelling constrained mixed-variable optimization problems is presented in a blackbox optimization context. The framework introduces a new notation and allows solution strategies. The notation framework allows…

Optimization and Control · Mathematics 2022-04-05 Charles Audet , Edward Hallé-Hannan , Sébastien Le Digabel

Complex systems are often decomposed into modular subsystems for engineering tractability. Although various equation based white-box modeling techniques make use of such structure, learning based methods have yet to incorporate these ideas…

Machine Learning · Computer Science 2022-10-31 Jayesh K. Gupta , Sai Vemprala , Ashish Kapoor

Black-box optimization (BBO) involves functions that are unknown, inexact and/or expensive-to-evaluate. Existing BBO algorithms face several challenges, including high computational cost from extensive evaluations, difficulty in handling…

Optimization and Control · Mathematics 2025-09-26 Zixuan Zhang , Xiaowei Song , Jiaming Li , Yujiao Zeng , Yaling Nie , Min Zhu , Dongyun Lu , Yibo Zhang , Xin Xiao , Jie Li

As evolutionary algorithms (EAs) are general-purpose optimization algorithms, recent theoretical studies have tried to analyze their performance for solving general problem classes, with the goal of providing a general theoretical…

Neural and Evolutionary Computing · Computer Science 2022-11-29 Chao Qian

Rapid advancements of deep learning are accelerating adoption in a wide variety of applications, including safety-critical applications such as self-driving vehicles, drones, robots, and surveillance systems. These advancements include…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Firuz Juraev , Mohammed Abuhamad , Simon S. Woo , George K Thiruvathukal , Tamer Abuhmed

As deep learning models are increasingly deployed in safety-critical applications, evaluating their vulnerabilities to adversarial perturbations is essential for ensuring their reliability and trustworthiness. Over the past decade, a large…

Machine Learning · Computer Science 2025-03-12 Yong Xie , Weijie Zheng , Hanxun Huang , Guangnan Ye , Xingjun Ma

Multi-modal methods establish comprehensive superiority over uni-modal methods. However, the imbalanced contributions of different modalities to task-dependent predictions constantly degrade the discriminative performance of canonical…

Machine Learning · Computer Science 2025-04-18 Yi Li , Fei Song , Changwen Zheng , Jiangmeng Li , Fuchun Sun , Hui Xiong

The difficulty of solving a multi-objective optimization problem is impacted by the number of objectives to be optimized. The presence of many objectives typically introduces a number of challenges that affect the choice/design of…

Artificial Intelligence · Computer Science 2021-06-08 Richard Allmendinger , Andrzej Jaszkiewicz , Arnaud Liefooghe , Christiane Tammer

Making each modality in multi-modal data contribute is of vital importance to learning a versatile multi-modal model. Existing methods, however, are often dominated by one or few of modalities during model training, resulting in sub-optimal…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Yangyang Guo , Liqiang Nie , Harry Cheng , Zhiyong Cheng , Mohan Kankanhalli , Alberto Del Bimbo

Estimating how individual input variables affect the output of a black-box model is a central task in explainable machine learning. However, existing methods suffer from two key limitations: sensitivity to out-of-distribution (OOD)…

Machine Learning · Statistics 2026-04-23 Chih-Yu Chang , Ming-Chung Chang

There is a long history in machine learning of model ensembling, beginning with boosting and bagging and continuing to the present day. Much of this history has focused on combining models for classification and regression, but recently…

Machine Learning · Computer Science 2024-05-28 Ira Globus-Harris , Varun Gupta , Michael Kearns , Aaron Roth

Performance-influence models can help stakeholders understand how and where configuration options and their interactions influence the performance of a system. With this understanding, stakeholders can debug performance behavior and make…

Software Engineering · Computer Science 2021-01-15 Miguel Velez , Pooyan Jamshidi , Norbert Siegmund , Sven Apel , Christian Kästner

Mixture variational distributions in black box variational inference (BBVI) have demonstrated impressive results in challenging density estimation tasks. However, currently scaling the number of mixture components can lead to a linear…

Machine Learning · Computer Science 2024-06-12 Alexandra Hotti , Oskar Kviman , Ricky Molén , Víctor Elvira , Jens Lagergren

Population diversity plays a key role in evolutionary algorithms that enables global exploration and avoids premature convergence. This is especially more crucial in dynamic optimization in which diversity can ensure that the population…

Neural and Evolutionary Computing · Computer Science 2019-10-15 Maryam Hasani-Shoreh , Frank Neumann

Bayesian Optimization (BO) is a class of black-box, surrogate-based heuristics that can efficiently optimize problems that are expensive to evaluate, and hence admit only small evaluation budgets. BO is particularly popular for solving…

Machine Learning · Computer Science 2024-06-25 Maria Laura Santoni , Elena Raponi , Renato De Leone , Carola Doerr