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Variational quantum algorithms offer fascinating prospects for the solution of combinatorial optimization problems using digital quantum computers. However, the achievable performance in such algorithms and the role of quantum correlations…

Quantum Physics · Physics 2024-01-10 Gopal Chandra Santra , Fred Jendrzejewski , Philipp Hauke , Daniel J. Egger

Quantum annealers (QAs) are specialized quantum computers that minimize objective functions over discrete variables by physically exploiting quantum effects. Current QA platforms allow for the optimization of quadratic objectives defined…

Emerging Technologies · Computer Science 2018-11-07 Zhengbing Bian , Fabian Chudak , William Macready , Aidan Roy , Roberto Sebastiani , Stefano Varotti

Platforms of Rydberg atoms have been proposed as promising candidates to solve some combinatorial optimization problems. Here, we compute quantitative requirements on the system sizes and noise levels that these platforms must fulfill to…

Quantum Physics · Physics 2021-07-27 Michel Fabrice Serret , Bertrand Marchand , Thomas Ayral

There has been considerable progress in the design and construction of quantum annealing devices. However, a conclusive detection of quantum speedup over traditional silicon-based machines remains elusive, despite multiple careful studies.…

Quantum Physics · Physics 2015-09-03 Helmut G. Katzgraber , Firas Hamze , Zheng Zhu , Andrew J. Ochoa , H. Munoz-Bauza

Quantum variational algorithms (QVAs) are increasingly potent tools for simulating quantum many-body systems on noisy intermediate-scale quantum (NISQ) devices. This work examines the application of the Variational Quantum Eigensolver (VQE)…

Nuclear Theory · Physics 2026-01-28 Dhritimalya Roy , Somnath Nag

Quantum computers hold immense potential in the field of chemistry, ushering new frontiers to solve complex many body problems that are beyond the reach of classical computers. However, noise in the current quantum hardware limits their…

Quantum Physics · Physics 2024-03-20 Chayan Patra , Sonaldeep Halder , Rahul Maitra

This work studies the variational quantum eigensolver algorithm, designed to determine the ground state of a quantum mechanical system by combining classical and quantum hardware. Methods of reducing the number of required qubit…

Quantum Physics · Physics 2022-03-01 R. J. P. T. de Keijzer , V. E. Colussi , B. Škorić , S. J. J. M. F. Kokkelmans

We present a quantum annealing-based solution method for topology optimization (TO). In particular, we consider TO in a more general setting, i.e., applied to structures of continuum domains where designs are represented as distributed…

Numerical Analysis · Mathematics 2023-01-30 Zisheng Ye , Xiaoping Qian , Wenxiao Pan

Quantum annealing is a promising paradigm for building practical quantum computers. Compared to other approaches, quantum annealing technology has been scaled up to a larger number of qubits. On the other hand, deep learning has been…

Quantum Physics · Physics 2021-07-07 Michele Sasdelli , Tat-Jun Chin

Quantum annealing is getting increasing attention in combinatorial optimization. The quantum processing unit by D-Wave is constructed to approximately solve Ising models on so-called Chimera graphs. Ising models are equivalent to quadratic…

Data Structures and Algorithms · Computer Science 2019-04-30 Michael Juenger , Elisabeth Lobe , Petra Mutzel , Gerhard Reinelt , Franz Rendl , Giovanni Rinaldi , Tobias Stollenwerk

As quantum computing advances, quantum approximate optimization algorithms (QAOA) have shown promise in addressing combinatorial optimization problems. However, the limitations of Noisy Intermediate Scale Quantum (NISQ) devices hinder the…

Benchmarking Quantum Process Units (QPU) at an application level usually requires considering the whole programming stack of the quantum computer. One critical task is the minor-embedding (resp. transpilation) step, which involves…

Quantum Physics · Physics 2024-08-02 Valentin Gilbert , Julien Rodriguez , Stéphane Louise

In this thesis, we focus on the problem of validating and benchmarking quantum annealers. To this end, we propose two algorithms for solving real-world problems and test how they perform on the current generation of quantum annealers. The…

Quantum Physics · Physics 2023-12-07 Konrad Jałowiecki

Methods to find the solution state for optimization problems encoded into Ising Hamiltonians are a very active area of current research. In this work we compare the quantum approximate optimization algorithm (QAOA) with multi-stage quantum…

Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos

To increase efficiency in automotive manufacturing, newly produced vehicles can move autonomously from the production line to the distribution area. This requires an optimal placement of sensors to ensure full coverage while minimizing the…

Emerging Technologies · Computer Science 2025-07-23 Nico Kraus , Marvin Erdmann , Alexander Kuzmany , Daniel Porawski , Jonas Stein

Quantum algorithms require accurate representations of electronic states on a quantum device, yet the approximation of electronic wave functions for strongly correlated systems remains a profound theoretical challenge, with existing methods…

Quantum Physics · Physics 2025-04-29 Dipanjali Halder , Dibyendu Mondal , Rahul Maitra

Developing quantum algorithms adaptive to specific constraints of near-term devices is an essential step towards practical quantum advantage. In a recent work [Phys. Rev. Lett. 131, 103601(2023)], we show cold atoms in an optical cavity can…

Quantum Physics · Physics 2024-06-12 Yuchen Luo , Xiaopeng Li , Jian Lin

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Quantum computing is a winsome field that concerns with the behaviour and nature of energy at the quantum level to improve the efficiency of computations. In recent years, quantum computation is receiving much attention for its capability…

Quantum Physics · Physics 2020-05-26 Amandeep Singh Bhatia , Ajay Kumar
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