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Recent work has shown that fine-tuning large language models (LLMs) on large-scale instruction-following datasets substantially improves their performance on a wide range of NLP tasks, especially in the zero-shot setting. However, even…

Computation and Language · Computer Science 2023-05-19 Kai Zhang , Bernal Jiménez Gutiérrez , Yu Su

Large Language Models (LLMs) have achieved remarkable success across various industries due to their exceptional generative capabilities. However, for safe and effective real-world deployments, ensuring honesty and helpfulness is critical.…

Computation and Language · Computer Science 2024-12-12 Chujie Gao , Siyuan Wu , Yue Huang , Dongping Chen , Qihui Zhang , Zhengyan Fu , Yao Wan , Lichao Sun , Xiangliang Zhang

An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive…

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Despite the utility of Large Language Models (LLMs) across a wide range of tasks and scenarios, developing a method for reliably evaluating LLMs across varied contexts continues to be challenging. Modern evaluation approaches often use LLMs…

Computation and Language · Computer Science 2024-01-31 Steffi Chern , Ethan Chern , Graham Neubig , Pengfei Liu

Conventional predictive modeling of parametric relationships in manufacturing processes is limited by the subjectivity of human expertise and intuition on the one hand and by the cost and time of experimental data generation on the other…

Computation and Language · Computer Science 2025-06-26 Kiarash Naghavi Khanghah , Anandkumar Patel , Rajiv Malhotra , Hongyi Xu

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Large Language Models (LLMs) show remarkable proficiency in natural language tasks, yet their frequent overconfidence-misalignment between predicted confidence and true correctness-poses significant risks in critical decision-making…

Computation and Language · Computer Science 2025-12-15 Prateek Chhikara

Large Language Models (LLMs) have achieved remarkable capabilities, yet their improvement methods remain fundamentally constrained by human design. We present Self-Developing, a framework that enables LLMs to autonomously discover,…

Computation and Language · Computer Science 2025-06-11 Yoichi Ishibashi , Taro Yano , Masafumi Oyamada

Large Language Models (LLMs) have shown strong capabilities in document re-ranking, a key component in modern Information Retrieval (IR) systems. However, existing LLM-based approaches face notable limitations, including ranking…

Information Retrieval · Computer Science 2025-10-03 Pinhuan Wang , Zhiqiu Xia , Chunhua Liao , Feiyi Wang , Hang Liu

Large Language Models (LLMs) have significantly advanced the state-of-the-art in various coding tasks. Beyond directly answering user queries, LLMs can also serve as judges, assessing and comparing the quality of responses generated by…

Computation and Language · Computer Science 2025-08-15 Hongchao Jiang , Yiming Chen , Yushi Cao , Hung-yi Lee , Robby T. Tan

Systematic reviews traditionally have taken considerable amounts of human time and energy to complete, in part due to the extensive number of titles and abstracts that must be reviewed for potential inclusion. Recently, researchers have…

Computation and Language · Computer Science 2026-03-27 Kweku Yamoah , Noah Schroeder , Emmanuel Dorley , Neha Rani , Caleb Schutz

Large language models (LLMs) have demonstrated remarkable capabilities across a wide range of tasks in various domains. Despite their impressive performance, they can be unreliable due to factual errors in their generations. Assessing their…

Computation and Language · Computer Science 2024-03-26 Jiahui Geng , Fengyu Cai , Yuxia Wang , Heinz Koeppl , Preslav Nakov , Iryna Gurevych

Conventional mechanical design follows an iterative process in which initial concepts are refined through cycles of expert assessment and resource-intensive Finite Element Method (FEM) analysis to meet performance goals. While machine…

Machine Learning · Computer Science 2025-05-02 Yayati Jadhav , Amir Barati Farimani

Despite the dramatic progress in Large Language Model (LLM) development, LLMs often provide seemingly plausible but not factual information, often referred to as hallucinations. Retrieval-augmented LLMs provide a non-parametric approach to…

Computation and Language · Computer Science 2023-11-09 Sai Munikoti , Anurag Acharya , Sridevi Wagle , Sameera Horawalavithana

This paper explores the potential of Large Language Models to accurately extract and translate equations from typed student responses into a standard format. This is a useful task as standardized equations can be graded reliably using a…

Physics Education · Physics 2025-12-17 Lachlan McGinness , Peter Baumgartner

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

Large language models (LLMs) deployed as agents solve user-specified tasks over multiple steps while keeping the required manual engagement to a minimum. Crucially, such LLMs need to ground their generations in any feedback obtained to…

Computation and Language · Computer Science 2025-02-19 Jonas Gehring , Kunhao Zheng , Jade Copet , Vegard Mella , Quentin Carbonneaux , Taco Cohen , Gabriel Synnaeve

Evaluating recommender systems remains a long-standing challenge, as offline methods based on historical user interactions and train-test splits often yield unstable and inconsistent results due to exposure bias, popularity bias, sampled…

Large Language Models (LLMs) have attracted extensive attention due to their remarkable performance across various tasks. However, the substantial computational and memory requirements of LLM inference pose challenges for deployment in…