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Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

A popular approach to model compression is to train an inexpensive student model to mimic the class probabilities of a highly accurate but cumbersome teacher model. Surprisingly, this two-step knowledge distillation process often leads to…

Machine Learning · Statistics 2021-04-21 Tri Dao , Govinda M Kamath , Vasilis Syrgkanis , Lester Mackey

Over the past years, embedding learning on networks has shown tremendous results in link prediction tasks for complex systems, with a wide range of real-life applications. Learning a representation for each node in a knowledge graph allows…

Machine Learning · Computer Science 2026-02-03 Orell Trautmann , Olaf Wolkenhauer , Clémence Réda

Recent advances in deep learning have facilitated the demand of neural models for real applications. In practice, these applications often need to be deployed with limited resources while keeping high accuracy. This paper touches the core…

Information Retrieval · Computer Science 2019-06-04 Bonggun Shin , Hao Yang , Jinho D. Choi

Purpose: In curriculum learning, the idea is to train on easier samples first and gradually increase the difficulty, while in self-paced learning, a pacing function defines the speed to adapt the training progress. While both methods…

Computer Vision and Pattern Recognition · Computer Science 2023-02-03 Mobarakol Islam , Lalithkumar Seenivasan , S. P. Sharan , V. K. Viekash , Bhavesh Gupta , Ben Glocker , Hongliang Ren

Version identification systems aim to detect different renditions of the same underlying musical composition (loosely called cover songs). By learning to encode entire recordings into plain vector embeddings, recent systems have made…

Sound · Computer Science 2020-10-08 Furkan Yesiler , Joan Serrà , Emilia Gómez

Recent advances in large-scale visual representation learning have significantly improved performance in plant species and plant disease recognition tasks. However, state-of-the-art models, often based on high-capacity vision transformers…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Ilyass Moummad , Reda Bensaid , Kawtar Zaher , Hervé Goëau , Jean-Christophe Lombardo , Joseph Salmon , Pierre Bonnet , Alexis Joly

Scaling neural networks to "large" sizes, with billions of parameters, has been shown to yield impressive results on many challenging problems. However, the inference cost incurred by such large models often prevents their application in…

Machine Learning · Computer Science 2021-10-22 Ankit Singh Rawat , Manzil Zaheer , Aditya Krishna Menon , Amr Ahmed , Sanjiv Kumar

Embedding models have become essential tools in both natural language processing and computer vision, enabling efficient semantic search, recommendation, clustering, and more. However, the high memory and computational demands of…

Computation and Language · Computer Science 2024-11-26 Jiayi Chen , Chen Wu , Shaoqun Zhang , Nan Li , Liangjie Zhang , Qi Zhang

Proteins perform a large variety of functions in living organisms, thus playing a key role in biology. As of now, available learning algorithms to process protein data do not consider several particularities of such data and/or do not scale…

Knowledge distillation is a powerful method for model compression, enabling the efficient deployment of complex deep learning models (teachers), including large language models. However, its underlying statistical mechanisms remain unclear,…

Methodology · Statistics 2026-05-28 Luyang Fang , Yongkai Chen , Jiazhang Cai , Ping Ma , Wenxuan Zhong

Many aspects of the study of protein folding and dynamics have been affected by the recent advances in machine learning. Methods for the prediction of protein structures from their sequences are now heavily based on machine learning tools.…

Biological Physics · Physics 2019-11-25 Frank Noé , Gianni De Fabritiis , Cecilia Clementi

We are now witnessing significant progress of deep learning methods in a variety of tasks (or datasets) of proteins. However, there is a lack of a standard benchmark to evaluate the performance of different methods, which hinders the…

Machine Learning · Computer Science 2022-09-20 Minghao Xu , Zuobai Zhang , Jiarui Lu , Zhaocheng Zhu , Yangtian Zhang , Chang Ma , Runcheng Liu , Jian Tang

Proteins play a vital role in biological processes and are indispensable for living organisms. Accurate representation of proteins is crucial, especially in drug development. Recently, there has been a notable increase in interest in…

Biomolecules · Quantitative Biology 2026-05-28 Dan Kalifa , Uriel Singer , Kira Radinsky

Deep learning technology has developed unprecedentedly in the last decade and has become the primary choice in many application domains. This progress is mainly attributed to a systematic collaboration in which rapidly growing computing…

Machine Learning · Computer Science 2023-12-27 Shiye Lei , Dacheng Tao

Model distillation aims to distill the knowledge of a complex model into a simpler one. In this paper, we consider an alternative formulation called dataset distillation: we keep the model fixed and instead attempt to distill the knowledge…

Machine Learning · Computer Science 2020-02-26 Tongzhou Wang , Jun-Yan Zhu , Antonio Torralba , Alexei A. Efros

High-quality computer vision models typically address the problem of understanding the general distribution of real-world images. However, most cameras observe only a very small fraction of this distribution. This offers the possibility of…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Ravi Teja Mullapudi , Steven Chen , Keyi Zhang , Deva Ramanan , Kayvon Fatahalian

Manifold learning techniques have become increasingly valuable as data continues to grow in size. By discovering a lower-dimensional representation (embedding) of the structure of a dataset, manifold learning algorithms can substantially…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Andrew Lensen , Mengjie Zhang , Bing Xue

Geometric deep learning has recently achieved great success in non-Euclidean domains, and learning on 3D structures of large biomolecules is emerging as a distinct research area. However, its efficacy is largely constrained due to the…

Machine Learning · Computer Science 2023-10-31 Fang Wu , Lirong Wu , Dragomir Radev , Jinbo Xu , Stan Z. Li

Deep learning techniques have achieved great success in many fields, while at the same time deep learning models are getting more complex and expensive to compute. It severely hinders the wide applications of these models. In order to…

Computation and Language · Computer Science 2021-04-20 Yongqi Li , Wenjie Li