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Causal discovery broadens the inference possibilities, as correlation does not inform about the relationship direction. The common approaches were proposed for cases in which prior knowledge is desired, when the impact of a…

Applications · Statistics 2018-07-18 Marcel Młyńczak

Context. Quantum computing is becoming a reality, and quantum software engineering (QSE) is emerging as a new discipline to enable developers to design and develop quantum programs. Objective. This paper presents a systematic mapping study…

Software Engineering · Computer Science 2023-06-02 Manuel De Stefano , Fabiano Pecorelli , Dario Di Nucci , Fabio Palomba , Andrea De Lucia

Identifying the relations between chemicals and proteins is an important text mining task. BioCreative VII track 1 DrugProt task aims to promote the development and evaluation of systems that can automatically detect relations between…

Computation and Language · Computer Science 2021-12-07 Mehmet Efruz Karabulut , K. Vijay-Shanker , Yifan Peng

Quantum computing has made tremendous improvements in both software and hardware that have sparked interest in academia and industry to realize quantum computing applications. To this end, several steps are necessary: The underlying problem…

The paper presents an application of Conformal Predictors to a chemoinformatics problem of identifying activities of chemical compounds. The paper addresses some specific challenges of this domain: a large number of compounds (training…

Machine Learning · Computer Science 2016-03-16 Paolo Toccacheli , Ilia Nouretdinov , Alexander Gammerman

The quest for effective quantum feature maps for data encoding presents significant challenges, particularly due to the flat training landscapes and lengthy training processes associated with parameterised quantum circuits. To address these…

Quantum Physics · Physics 2025-08-12 Yaswitha Gujju , Romain Harang , Chao Li , Tetsuo Shibuya , Qibin Zhao

Polynomial dynamical systems (DSs) can model a wide range of physical processes. A special subset of these DSs that can model chemical reactions under mass-action kinetics is called chemical dynamical systems (CDSs). A fundamental problem,…

Molecular Networks · Quantitative Biology 2025-08-04 Tomislav Plesa

Automatically extracting effective queries is challenging in information retrieval, especially in toxic content exploration, as such content is likely to be disguised. With the recent achievements in generative Large Language Model (LLM),…

Information Retrieval · Computer Science 2025-02-27 Shaola Ren , Li Ke , Longtao Huang , Dehong Gao , Hui Xue

We present QDK/Chemistry, a software toolkit for quantum chemistry workflows targeting quantum computers. The toolkit addresses a key challenge in the field: while quantum algorithms for chemistry have matured considerably, the…

A force field is a critical component in molecular dynamics simulations for computational drug discovery. It must achieve high accuracy within the constraints of molecular mechanics' (MM) limited functional forms, which offers high…

Machine Learning · Computer Science 2024-10-10 Tianze Zheng , Ailun Wang , Xu Han , Yu Xia , Xingyuan Xu , Jiawei Zhan , Yu Liu , Yang Chen , Zhi Wang , Xiaojie Wu , Sheng Gong , Wen Yan

Data-driven inference was recently introduced as a protocol that, upon the input of a set of data, outputs a mathematical description for a physical device able to explain the data. The device so inferred is automatically self-consistent,…

Quantum Physics · Physics 2021-12-10 Michele Dall'Arno , Asaph Ho , Francesco Buscemi , Valerio Scarani

Predicting the chemical properties of compounds is crucial in discovering novel materials and drugs with specific desired characteristics. Recent significant advances in machine learning technologies have enabled automatic predictive…

Quantitative Methods · Quantitative Biology 2021-12-10 Yang Liu , Hisashi Kashima

Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts…

Artificial Intelligence · Computer Science 2025-05-13 Sumyyah Toonsi , Paul Schofield , Robert Hoehndorf

Activity coefficients, which are a measure of the non-ideality of liquid mixtures, are a key property in chemical engineering with relevance to modeling chemical and phase equilibria as well as transport processes. Although experimental…

Drug synergy prediction is a critical task in the development of effective combination therapies for complex diseases, including cancer. Although existing methods have shown promising results, they often operate as black-box predictors that…

Machine Learning · Computer Science 2025-11-05 Yi Luo , Haochen Zhao , Xiao Liang , Yiwei Liu , Yuye Zhang , Xinyu Li , Jianxin Wang

Information on the structure of molecules, retrieved via biochemical databases, plays a pivotal role in various disciplines, such as metabolomics, systems biology, and drug discovery. However, no such database can be complete, and the…

Biomolecules · Quantitative Biology 2023-08-25 Casper Asbjørn Eriksen , Jakob Lykke Andersen , Rolf Fagerberg , Daniel Merkle

Complementarity, the incomplete nature of a quantum measurement - a core concept in quantum mechanics - stems from the choice of the measurement apparatus. The notion of complementarity is closely related to Heisenberg's uncertainty…

Mesoscale and Nanoscale Physics · Physics 2015-06-17 E. Weisz , H. K. Choi , I. Sivan , M. Heiblum , Y. Gefen , D. Mahalu , V. Umansky

Causal modeling has long been an attractive topic for many researchers and in recent decades there has seen a surge in theoretical development and discovery algorithms. Generally discovery algorithms can be divided into two approaches:…

Machine Learning · Statistics 2017-02-06 Ridho Rahmadi , Perry Groot , Marianne Heins , Hans Knoop , Tom Heskes

The noisy matrix completion problem, which aims to recover a low-rank matrix $\mathbf{X}$ from a partial, noisy observation of its entries, arises in many statistical, machine learning, and engineering applications. In this paper, we…

Methodology · Statistics 2021-07-15 Simon Mak , Henry Shaowu Yushi , Yao Xie

Recently, a quantum algorithm for a fundamentally important task in data mining, association rules mining (ARM), called qARM for short, has been proposed. Notably, qARM achieves significant speedup over its classical counterpart for…

Quantum Physics · Physics 2022-09-07 Chao-Hua Yu