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Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Background/Objectives: Age-related macular degeneration, glaucoma, diabetic retinopathy (DR), diabetic macular edema, and pathological myopia affect hundreds of millions of people worldwide. Early screening for these diseases is essential,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Ananya Raghu , Anisha Raghu , Alice S. Tang , Yannis M. Paulus , Tyson N. Kim , Tomiko T. Oskotsky

The development of medical vision-language foundation models has attracted significant attention in the field of medicine and healthcare due to their promising prospect in various clinical applications. While previous studies have commonly…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Weijian Huang , Cheng Li , Hong-Yu Zhou , Jiarun Liu , Hao Yang , Yong Liang , Guangming Shi , Hairong Zheng , Shanshan Wang

The automatic diagnosis of various retinal diseases from fundus images is important to support clinical decision-making. However, developing such automatic solutions is challenging due to the requirement of a large amount of human-annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xiaomeng Li , Mengyu Jia , Md Tauhidul Islam , Lequan Yu , Lei Xing

Developing a single foundation model with the capability to excel across diverse tasks has been a long-standing objective in the field of artificial intelligence. As the wave of general-purpose foundation models sweeps across various…

Information Retrieval · Computer Science 2025-07-02 Zheli Zhou , Chenxu Zhu , Jianghao Lin , Bo Chen , Ruiming Tang , Weinan Zhang , Yong Yu

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

This paper presents a comprehensive survey of the taxonomy and evolution of multimodal foundation models that demonstrate vision and vision-language capabilities, focusing on the transition from specialist models to general-purpose…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Chunyuan Li , Zhe Gan , Zhengyuan Yang , Jianwei Yang , Linjie Li , Lijuan Wang , Jianfeng Gao

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related mortality in women globally. Mammography is essential for the early detection and diagnosis of breast lesions. Despite recent progress in foundation…

Multimodal foundation models have demonstrated impressive capabilities across diverse tasks. However, their potential as plug-and-play solutions for missing modality reconstruction remains underexplored. To bridge this gap, we identify and…

Multimedia · Computer Science 2026-05-25 Guanzhou Ke , Bo Wang , Guoqing Chao , Weiming Hu , Shengfeng He

Retinal image registration plays an important role in the ophthalmological diagnosis process. Since there exist variances in viewing angles and anatomical structures across different retinal images, keypoint-based approaches become the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Yepeng Liu , Baosheng Yu , Tian Chen , Yuliang Gu , Bo Du , Yongchao Xu , Jun Cheng

Vision foundation models like DINOv2 demonstrate remarkable potential in medical imaging despite their origin in natural image domains. However, their design inherently works best for uni-modal image analysis, limiting their effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Viktoria Ehm , Anke Meyer-Baese , Jan C. Peeken , Daniel Rueckert , Benedikt Wiestler

Fundus diseases are major causes of visual impairment and blindness worldwide, especially in underdeveloped regions, where the shortage of ophthalmologists hinders timely diagnosis. AI-assisted fundus image analysis has several advantages,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Yong Liu , Mengtian Kang , Shuo Gao , Chi Zhang , Ying Liu , Shiming Li , Yue Qi , Arokia Nathan , Wenjun Xu , Chenyu Tang , Edoardo Occhipinti , Mayinuer Yusufu , Ningli Wang , Weiling Bai , Luigi Occhipinti

The rapid evolution of AI-generated images poses growing challenges to information integrity and media authenticity. Existing detection approaches face limitations in robustness, interpretability, and generalization across diverse…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Mengfei Liang , Yiting Qu , Yukun Jiang , Michael Backes , Yang Zhang

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Hospitals and healthcare systems rely on operational decisions that determine patient flow, cost, and quality of care. Despite strong performance on medical knowledge and conversational benchmarks, foundation models trained on general text…

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

Foundation models (FMs) are catalyzing a transformative shift in materials science (MatSci) by enabling scalable, general-purpose, and multimodal AI systems for scientific discovery. Unlike traditional machine learning models, which are…

Machine Learning · Computer Science 2025-06-27 Minh-Hao Van , Prateek Verma , Chen Zhao , Xintao Wu

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

Retinal foundation models have significantly advanced retinal image analysis by leveraging self-supervised learning to reduce dependence on labeled data while achieving strong generalization. Many recent approaches enhance retinal image…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yeonkyung Lee , Woojung Han , Youngjun Jun , Hyeonmin Kim , Jungkyung Cho , Seong Jae Hwang

Multimodal foundation models that can holistically process text alongside images, video, audio, and other sensory modalities are increasingly used in a variety of real-world applications. However, it is challenging to characterize and study…