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The nonparametric formulation of density-based clustering, known as modal clustering, draws a correspondence between groups and the attraction domains of the modes of the density function underlying the data. Its probabilistic foundation…

Methodology · Statistics 2020-10-27 Federico Ferraccioli , Giovanna Menardi

The rapid emergence of single-cell data has facilitated the study of many different biological conditions at the cellular level. Cluster analysis has been widely applied to identify cell types, capturing the essential patterns of the…

Genomics · Quantitative Biology 2025-02-03 Sebastian Pena , Lin Lin , Jia Li

In this work, we address the problem of learning an ensemble of specialist networks using multimodal data, while considering the realistic and challenging scenario of possible missing modalities at test time. Our goal is to leverage the…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Nuno C. Garcia , Sarah Adel Bargal , Vitaly Ablavsky , Pietro Morerio , Vittorio Murino , Stan Sclaroff

Real-world multimodal machine learning often faces missing, costly-to-acquire modalities, raising the problem of which samples to prioritize for additional acquisition under a budget. Prior work mainly studies per-sample or training-time…

Machine Learning · Computer Science 2026-05-08 Tillmann Rheude , Roland Eils , Benjamin Wild

Data for several applications in diverse fields can be represented as multiple matrices that are linked across rows or columns. This is particularly common in molecular biomedical research, in which multiple molecular "omics" technologies…

Machine Learning · Statistics 2024-08-02 Eric F. Lock

Representation learning is typically applied to only one mode of a data matrix, either its rows or columns. Yet in many applications, there is an underlying geometry to both the rows and the columns. We propose utilizing this coupled…

Machine Learning · Statistics 2018-10-17 Gal Mishne , Eric C. Chi , Ronald R. Coifman

In real-world scenarios, achieving domain generalization (DG) presents significant challenges as models are required to generalize to unknown target distributions. Generalizing to unseen multi-modal distributions poses even greater…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Hao Dong , Ismail Nejjar , Han Sun , Eleni Chatzi , Olga Fink

Important tasks in the study of genomic data include the identification of groups of similar cells (for example by clustering), and visualisation of data summaries (for example by dimensional reduction). In this paper, we develop a novel…

Methodology · Statistics 2024-10-15 Thomas E. Bartlett , Swati Chandna , Sandipan Roy

Recently, we have witnessed impressive achievements in cancer survival analysis by integrating multimodal data, e.g., pathology images and genomic profiles. However, the heterogeneity and high dimensionality of these modalities pose…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Huajun Zhou , Fengtao Zhou , Hao Chen

Cognitive diagnosis is a crucial task in computational education, aimed at evaluating students' proficiency levels across various knowledge concepts through exercises. Current models, however, primarily rely on students' answered exercises,…

Computers and Society · Computer Science 2023-12-19 Haiping Ma , Changqian Wang , Hengshu Zhu , Shangshang Yang , Xiaoming Zhang , Xingyi Zhang

Over the past few years, technological advances have allowed for measurement of omics data at the cell level, creating a new type of data generally referred to as single-cell (sc) omics. On the other hand, the so-called spatial omics are a…

High-throughput omics profiling advancements have greatly enhanced cancer patient stratification. However, incomplete data in multi-omics integration presents a significant challenge, as traditional methods like sample exclusion or…

Genomics · Quantitative Biology 2024-01-17 Shihao Ma , Andy G. X. Zeng , Benjamin Haibe-Kains , Anna Goldenberg , John E Dick , Bo Wang

With the rapid growth of various types of multimodal data, cross-modal deep hashing has received broad attention for solving cross-modal retrieval problems efficiently. Most cross-modal hashing methods follow the traditional supervised…

Information Retrieval · Computer Science 2019-02-05 Shifeng Zhang , Jianmin Li , Bo Zhang

An important objective in computational biology is the efficient integration of multi-omics data. The task of integration comes with challenges: multi-omics data are most often unpaired (requiring diagonal integration), partially labeled…

Machine Learning · Computer Science 2025-09-16 Daniel Lepe-Soltero , Thierry Artières , Anaïs Baudot , Paul Villoutreix

Class-Incremental Learning (CIL) requires a learning system to learn new classes while retaining previously learned knowledge. However, in real-world scenarios such as autonomous driving, a system trained on urban roads in sunny weather may…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zhen-Hao Xie , Yan Wang , Hao Sun , Han-Jia Ye , De-Chuan Zhan , Da-Wei Zhou

The distinct characteristics of multiomics data, including complex interactions within and across biological layers and disease heterogeneity (e.g., heterogeneity in etiology and clinical symptoms), drive us to develop novel designs to…

Machine Learning · Computer Science 2024-11-14 Shan Cong , Zhiling Sang , Hongwei Liu , Haoran Luo , Xin Wang , Hong Liang , Jie Hao , Xiaohui Yao

With the exponential surge in diverse multi-modal data, traditional uni-modal retrieval methods struggle to meet the needs of users seeking access to data across various modalities. To address this, cross-modal retrieval has emerged,…

Information Retrieval · Computer Science 2024-10-01 Tianshi Wang , Fengling Li , Lei Zhu , Jingjing Li , Zheng Zhang , Heng Tao Shen

Many fields, such as neuroscience, are experiencing the vast proliferation of cellular data, underscoring the need for organizing and interpreting large datasets. A popular approach partitions data into manageable subsets via hierarchical…

Quantitative Methods · Quantitative Biology 2024-03-07 Diek W. Wheeler , Giorgio A. Ascoli

This paper presents a framework based on matrices of monoids for the study of coupled cell networks. We formally prove within the proposed framework, that the set of results about invariant synchrony patterns for unweighted networks also…

Multiagent Systems · Computer Science 2022-01-13 Pedro M. Sequeira , António P. Aguiar , João Hespanha

Relationship between agents can be conveniently represented by graphs. When these relationships have different modalities, they are better modelled by multilayer graphs where each layer is associated with one modality. Such graphs arise…

Machine Learning · Statistics 2021-03-05 Guillaume Braun , Hemant Tyagi , Christophe Biernacki
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