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Determining lymphoma subtypes is a crucial step for better patient treatment targeting to potentially increase their survival chances. In this context, the existing gold standard diagnosis method, which relies on gene expression technology,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Marianne Petit , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

The precise categorization of white blood cell (WBC) is crucial for diagnosing blood-related disorders. However, manual analysis in clinical settings is time-consuming, labor-intensive, and prone to errors. Numerous studies have employed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Yuzhuo Chen , Zetong Chen , Yunuo An , Chenyang Lu , Xu Qiao

Modern machine learning pipelines, in particular those based on deep learning (DL) models, require large amounts of labeled data. For classification problems, the most common learning paradigm consists of presenting labeled examples during…

Computer Vision and Pattern Recognition · Computer Science 2022-11-30 Jacopo Teneggi , Paul H. Yi , Jeremias Sulam

While analysing rare blood cell aggregates remains challenging in automated haematology, they could markedly advance label-free functional diagnostics. Conventional flow cytometers efficiently perform cell counting with leukocyte…

In numerous studies, deep learning algorithms have proven their potential for the analysis of histopathology images, for example, for revealing the subtypes of tumors or the primary origin of metastases. These models require large datasets…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Jonathan Ganz , Jonas Ammeling , Samir Jabari , Katharina Breininger , Marc Aubreville

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

Due to morphological similarity at the microscopic level, making an accurate and time-sensitive distinction between blood cells affected by Acute Lymphocytic Leukemia (ALL) and their healthy counterparts calls for the usage of machine…

Computer Vision and Pattern Recognition · Computer Science 2022-07-29 Sai Mattapalli , Rishi Athavale

White blood cells, also known as leukocytes are group of heterogeneously nucleated cells which act as salient immune system cells. These are originated in the bone marrow and are found in blood, plasma, and lymph tissues. Leukocytes kill…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Shrijeet Biswas , Amartya Bhattacharya

While skin cancer detection has been a valuable deep learning application for years, its evaluation has often neglected the context in which testing images are assessed. Traditional melanoma classifiers assume that their testing…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nick DiSanto , Gavin Harding , Ethan Martinez , Benjamin Sanders

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia

Anemia, a condition marked by insufficient levels of red blood cells or hemoglobin, remains a widespread health issue affecting millions of individuals globally. Accurate and timely diagnosis is essential for effective management and…

We present a foundation modeling framework that leverages deep learning to uncover latent genetic signatures across the hematopoietic hierarchy. Our approach trains a fully connected autoencoder on multipotent progenitor cells, reducing…

Machine Learning · Computer Science 2025-03-27 Gabriel Bo , Justin Gu , Christopher Sun

Hematological disorders, which involve a variety of malignant conditions and genetic diseases affecting blood formation, present significant diagnostic challenges. One such major challenge in clinical settings is differentiating…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Buddhadev Goswami , Adithya B. Somaraj , Prantar Chakrabarti , Ravindra Gudi , Nirmal Punjabi

Modeling of the red blood cell (RBC) shape is an integral part of the experimental and computer simulation investigations of light scattering by these cells for fundamental studies as well as diagnostic applications in techniques like…

Biological Physics · Physics 2024-06-18 Gaurav D. Bhabhor , Chetna Patel , Nishant Chhillar , Arun Anand , Kirit N. Lad

The advent of digital pathology presents opportunities for computer vision for fast, accurate, and objective solutions for histopathological images and aid in knowledge discovery. This work uses deep learning to predict genomic biomarkers -…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Ruchi Chauhan , PK Vinod , CV Jawahar

We describe a new multiresolution "nested encoder-decoder" convolutional network architecture and use it to annotate morphological patterns in reflectance confocal microscopy (RCM) images of human skin for aiding cancer diagnosis. Skin…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Alican Bozkurt , Kivanc Kose , Christi Alessi-Fox , Melissa Gill , Dana H. Brooks , Jennifer G. Dy , Milind Rajadhyaksha

Using deep learning models to diagnose cancer from histology data presents several challenges. Cancer grading and localization of regions of interest (ROIs) in these images normally relies on both image- and pixel-level labels, the latter…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Jérôme Rony , Soufiane Belharbi , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Hematoxylin and Eosin (H&E)-stained images are commonly used to detect nuclear or cancerous regions in cells from images captured by a microscope. Identifying cancer cytoplasm is crucial for determining the type of cancer; hence, obtaining…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Rebeka Sultana , Hibiki Horibe , Tomoaki Murakami , Ikuko Shimizu

This paper proposes a novel automatic classification framework for the recognition of five types of white blood cells. Segmenting complete white blood cells from blood smears images and extracting advantageous features from them remain…

Computer Vision and Pattern Recognition · Computer Science 2020-09-07 Na Dong , Meng-die Zhai , Jian-fang Chang , Chun-ho Wu

Human immune system contains white blood cells (WBC) that are good indicator of many diseases like bacterial infections, AIDS, cancer, spleen, etc. White blood cells have been sub classified into four types: monocytes, lymphocytes,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Rabia Asghar , Arslan Shaukat , Usman Akram , Rimsha Tariq
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