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Motivated by mutation processes occurring in in-vivo DNA-storage applications, a channel that mutates stored strings by duplicating substrings as well as substituting symbols is studied. Two models of such a channel are considered: one in…

Information Theory · Computer Science 2020-07-01 Yuanyuan Tang , Yonatan Yehezkeally , Moshe Schwartz , Farzad Farnoud

We consider a new family of codes, termed asymmetric Lee distance codes, that arise in the design and implementation of DNA-based storage systems and systems with parallel string transmission protocols. The codewords are defined over a…

Information Theory · Computer Science 2016-12-16 Ryan Gabrys , Han Mao Kiah , Olgica Milenkovic

The short lifespan of traditional data storage media, coupled with an exponential increase in storage demand, has made long-term archival a fundamental problem in the data storage industry and beyond. Consequently, researchers are looking…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Xavier Pic , Nimesh Pinnamaneni , Raja Appuswamy

Data compression is a well-studied (and well-solved) problem in the setup of long coding blocks. But important emerging applications need to compress data to memory words of small fixed widths. This new setup is the subject of this paper.…

Information Theory · Computer Science 2017-01-12 Ori Rottenstreich , Yuval Cassuto

Constrained codes are used to prevent errors from occurring in various data storage and data transmission systems. They can help in increasing the storage density of magnetic storage devices, in managing the lifetime of electronic storage…

Information Theory · Computer Science 2022-09-07 Ahmed Hareedy , Beyza Dabak , Robert Calderbank

DNA-based storage has emerged as a promising alternative to traditional data storage methods, offering unmatched advantages in data density, longevity, and sustainability. Two main approaches have developed: in-vitro storage, where…

Information Theory · Computer Science 2026-04-29 Liav Koram , Ohad Elishco

In terabit-density magnetic recording, several bits of data can be replaced by the values of their neighbors in the storage medium. As a result, errors in the medium are dependent on each other and also on the data written. We consider a…

Information Theory · Computer Science 2011-11-23 Arya Mazumdar , Alexander Barg , Navin Kashyap

Effective and reliable data retrieval is critical for the feasibility of DNA storage, and the development of random access efficiency plays a key role in its practicality and reliability. In this paper, we study the Random Access Problem,…

Information Theory · Computer Science 2025-10-10 Anina Gruica , Maria Montanucci , Ferdinando Zullo

The efficient storage of digital data is becoming very challenging over the years due to the exponential increase in the generation of data which can't compete with the existing storage resources. Furthermore, the infrequently accessed data…

Emerging Technologies · Computer Science 2021-03-18 Melpomeni Dimopoulou , Eva Gil San Antonio , Marc Antonini

In this paper, we study the Random Access Problem in DNA storage, which addresses the challenge of retrieving a specific information strand from a DNA-based storage system. In this framework, the data is represented by $k$ information…

Information Theory · Computer Science 2025-08-26 Avital Boruchovsky , Ohad Elishco , Ryan Gabrys , Anina Gruica , Itzhak Tamo , Eitan Yaakobi

Synthetic polymer-based storage seems to be a particularly promising candidate that could help to cope with the ever-increasing demand for archival storage requirements. It involves designing molecules of distinct masses to represent the…

Information Theory · Computer Science 2026-04-02 Anisha Banerjee , Antonia Wachter-Zeh , Eitan Yaakobi

The emerging field of DNA storage employs strands of DNA bases (A/T/C/G) as a storage medium for digital information to enable massive density and durability. The DNA storage pipeline includes: (1) encoding the raw data into sequences of…

Genomics · Quantitative Biology 2025-01-28 Hadas Abraham , Barak Gahtan , Adir Kobovich , Orian Leitersdorf , Alex M. Bronstein , Eitan Yaakobi

We construct integer error-correcting codes and covering codes for the limited-magnitude error channel with more than one error. The codes are lattices that pack or cover the space with the appropriate error ball. Some of the constructions…

Information Theory · Computer Science 2020-06-01 Hengjia Wei , Xin Wang , Moshe Schwartz

In the current era, DeoxyriboNucleic Acid (DNA) based data storage emerges as an intriguing approach, garnering substantial academic interest and investigation. This paper introduces a novel deep joint source-channel coding (DJSCC) scheme…

Emerging Technologies · Computer Science 2023-11-03 Wenfeng Wu , Luping Xiang , Qiang Liu , Kun Yang

To equip DNA-based data storage with random-access capabilities, Yazdi et al. (2018) prepended DNA strands with specially chosen address sequences called primers and provided certain design criteria for these primers. We provide explicit…

Information Theory · Computer Science 2019-01-07 Yeow Meng Chee , Han Mao Kiah , Hengjia Wei

To make DNA a suitable medium for archival data storage, it is essential to consider the decay process of the strands observed in DNA storage systems. This paper studies the decay process as a probabilistic noisy torn paper channel (TPC),…

Information Theory · Computer Science 2026-01-19 Frederik Walter , Maria Abu-Sini , Nils Weinhardt , Antonia Wachter-Zeh

This paper presents and analyzes a novel concatenated coding scheme for enabling error resilience in two distributed storage settings: one being storage using existing regenerating codes and the second being storage using locally repairable…

Information Theory · Computer Science 2013-12-12 Natalia Silberstein , Ankit Singh Rawat , Sriram Vishwanath

As DNA data storage moves closer to practical deployment, minimizing sequencing coverage depth is essential to reduce both operational costs and retrieval latency. This paper addresses the recently studied Random Access Problem, which…

Information Theory · Computer Science 2026-01-13 Chen Wang , Eitan Yaakobi

Most low-density parity-check (LDPC) code constructions are considered over finite fields. In this work, we focus on regular LDPC codes over integer residue rings and analyze their performance with respect to the Lee metric. Their…

Information Theory · Computer Science 2024-08-01 Jessica Bariffi , Hannes Bartz , Gianluigi Liva , Joachim Rosenthal

Recent experiments have shown that the capacity of DNA storage systems may be significantly increased by synthesizing composite DNA letters. In this work, we model a DNA storage channel with composite inputs as a \textit{multinomial…

Information Theory · Computer Science 2025-01-28 Adir Kobovich , Eitan Yaakobi , Nir Weinberger