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Automatic multiple sclerosis (MS) lesion segmentation using multi-contrast magnetic resonance (MR) images provides improved efficiency and reproducibility compared to manual delineation. Current state-of-the-art automatic MS lesion…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Jinwei Zhang , Lianrui Zuo , Blake E. Dewey , Samuel W. Remedios , Dzung L. Pham , Aaron Carass , Jerry L. Prince

Fully convolutional neural networks (CNNs) have proven to be effective at representing and classifying textural information, thus transforming image intensity into output class masks that achieve semantic image segmentation. In medical…

Computer Vision and Pattern Recognition · Computer Science 2019-09-12 Ali Hatamizadeh , Demetri Terzopoulos , Andriy Myronenko

In this study, we propose MoME, a Mixture of Visual Language Medical Experts, for Medical Image Segmentation. MoME adapts the successful Mixture of Experts (MoE) paradigm, widely used in Large Language Models (LLMs), for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Arghavan Rezvani , Xiangyi Yan , Anthony T. Wu , Kun Han , Pooya Khosravi , Xiaohui Xie

Multi-modal MR imaging is routinely used in clinical practice to diagnose and investigate brain tumors by providing rich complementary information. Previous multi-modal MRI segmentation methods usually perform modal fusion by concatenating…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Zhaohu Xing , Lequan Yu , Liang Wan , Tong Han , Lei Zhu

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

Deep learning models such as convolutional neural net- work have been widely used in 3D biomedical segmentation and achieve state-of-the-art performance. However, most of them often adapt a single modality or stack multiple modalities as…

Computer Vision and Pattern Recognition · Computer Science 2017-04-26 Kuan-Lun Tseng , Yen-Liang Lin , Winston Hsu , Chung-Yang Huang

Brain tumor segmentation is one of the most challenging problems in medical image analysis. The goal of brain tumor segmentation is to generate accurate delineation of brain tumor regions. In recent years, deep learning methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Zhihua Liu , Lei Tong , Zheheng Jiang , Long Chen , Feixiang Zhou , Qianni Zhang , Xiangrong Zhang , Yaochu Jin , Huiyu Zhou

In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach is based on a cascade of two 3D patch-wise convolutional neural networks (CNN). The first…

When it comes to clinical images, automatic segmentation has a wide variety of applications and a considerable diversity of input domains, such as different types of Magnetic Resonance Images (MRIs) and Computerized Tomography (CT) scans.…

Image and Video Processing · Electrical Eng. & Systems 2024-02-28 Matteo Bastico , David Ryckelynck , Laurent Corté , Yannick Tillier , Etienne Decencière

Brain tumor segmentation based on multi-modal magnetic resonance imaging (MRI) plays a pivotal role in assisting brain cancer diagnosis, treatment, and postoperative evaluations. Despite the achieved inspiring performance by existing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-16 Haoran Li , Cheng Li , Weijian Huang , Xiawu Zheng , Yan Xi , Shanshan Wang

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Lijun Yan , Churan Wang , Fangwei Zhong , Yizhou Wang

Segmentation of focal (localized) brain pathologies such as brain tumors and brain lesions caused by multiple sclerosis and ischemic strokes are necessary for medical diagnosis, surgical planning and disease development as well as other…

Computer Vision and Pattern Recognition · Computer Science 2017-01-25 Mohammad Havaei , Nicolas Guizard , Hugo Larochelle , Pierre-Marc Jodoin

Magnetic resonance imaging (MRI) is critically important for brain mapping in both scientific research and clinical studies. Precise segmentation of brain tumors facilitates clinical diagnosis, evaluations, and surgical planning. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Rui Nian , Guoyao Zhang , Yao Sui , Yuqi Qian , Qiuying Li , Mingzhang Zhao , Jianhui Li , Ali Gholipour , Simon K. Warfield

The striking alignment between large language models (LLMs) and human brain activity positions them as powerful models of healthy cognition. This parallel raises a fundamental question: if LLMs can model the intact brain, can we lesion them…

Neurons and Cognition · Quantitative Biology 2025-08-08 Yifan Wang , Jingyuan Sun , Jichen Zheng , Yunhao Zhang , Chunyu Ye , Jixing Li , Chengqing Zong , Shaonan Wang

Medical image segmentation (MIS) plays an instrumental role in medical image analysis, where considerable effort has been devoted to automating the process. Currently, mainstream MIS approaches are based on deep neural networks (DNNs),…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Binyan Hu , A. K. Qin

The intricate morphology of brain vessels poses significant challenges for automatic segmentation models, which usually focus on a single imaging modality. However, accurately treating brain-related conditions requires a comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Francesco Galati , Daniele Falcetta , Rosa Cortese , Ferran Prados , Ninon Burgos , Maria A. Zuluaga

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies

Medical image and video segmentation is a critical task for precision medicine, which has witnessed considerable progress in developing task or modality-specific and generalist models for 2D images. However, there have been limited studies…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Jun Ma , Zongxin Yang , Sumin Kim , Bihui Chen , Mohammed Baharoon , Adibvafa Fallahpour , Reza Asakereh , Hongwei Lyu , Bo Wang

In the field of healthcare, precise skin lesion segmentation is crucial for the early detection and accurate diagnosis of skin diseases. Despite significant advances in deep learning for image processing, existing methods have yet to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Siyu Wang , Hua Wang , Huiyu Li , Fan Zhang