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Test-time adaptation (TTA) has increasingly been an important topic to efficiently tackle the cross-domain distribution shift at test time for medical images from different institutions. Previous TTA methods have a common limitation of…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Hongzheng Yang , Cheng Chen , Meirui Jiang , Quande Liu , Jianfeng Cao , Pheng Ann Heng , Qi Dou

Real-time cone-beam computed tomography (CBCT) provides instantaneous visualization of patient anatomy for image guidance, motion tracking, and online treatment adaptation in radiotherapy. While many real-time imaging and motion tracking…

Medical Physics · Physics 2024-09-27 Hua-Chieh Shao , Tielige Mengke , Tinsu Pan , You Zhang

One of the main goals of sequential, multiple assignment, randomized trials (SMART) is to find the most efficacious design embedded dynamic treatment regimes. The analysis method known as multiple comparisons with the best (MCB) allows…

Methodology · Statistics 2020-08-07 William J. Artman , Ashkan Ertefaie , Kevin G. Lynch , James R. McKay

Multimodal MR-US registration is critical for prostate cancer diagnosis. However, this task remains challenging due to significant modality discrepancies. Existing methods often fail to align critical boundaries while being overly sensitive…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Xudong Ma , Nantheera Anantrasirichai , Stefanos Bolomytis , Alin Achim

Airborne Base Stations (ABSs) allow for flexible geographical allocation of network resources with dynamically changing load as well as rapid deployment of alternate connectivity solutions during natural disasters. Since the radio…

Networking and Internet Architecture · Computer Science 2025-10-27 Mauro Belgiovine , Chris Dick , Kaushik Chowdhury

The question of whether or not neutron therapy works has been answered. It is a qualified yes, as is the case with all of radiation therapy. But, neutron therapy has not kept pace with the rest of radiation therapy in terms of beam delivery…

Medical Physics · Physics 2014-09-09 Thomas K. Kroc , James S. Welsh

When treating moving tumors, the precise delivery of proton therapy by pencil beam scanning (PBS) is challenged by the interplay effect. Although several 4D-optimization methods have been proposed, what is the most beneficial motion…

Medical Physics · Physics 2025-01-29 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson

This article presents a digital twin (DT)-enhanced reinforcement learning (RL) framework aimed at optimizing performance and reliability in network resource management, since the traditional RL methods face several unified challenges when…

Systems and Control · Electrical Eng. & Systems 2024-06-18 Nan Cheng , Xiucheng Wang , Zan Li , Zhisheng Yin , Tom Luan , Xuemin Shen

Intelligent fault diagnosis (IFD) has emerged as a powerful paradigm for ensuring the safety and reliability of industrial machinery. However, traditional IFD methods rely heavily on abundant labeled data for training, which is often…

Artificial Intelligence · Computer Science 2026-03-10 Pengcheng Xia , Zhichao Dong , Yixiang Huang , Chengjin Qin , Qun Chao , Chengliang Liu

Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range uncertainties, and computational complexity. This review…

In the manufacturing industry, the digital twin (DT) is becoming a central topic. It has the potential to enhance the efficiency of manufacturing machines and reduce the frequency of errors. In order to fulfill its purpose, a DT must be an…

Systems and Control · Electrical Eng. & Systems 2024-08-26 Zhibo Zhou , Michael Walther , Alexander Verl

Predicting clinical outcomes to anti-cancer drugs on a personalized basis is challenging in cancer treatment due to the heterogeneity of tumors. Traditional computational efforts have been made to model the effect of drug response on…

Machine Learning · Computer Science 2022-07-12 Jie Gao , Jing Hu , Wanqing Sun , Yili Shen , Xiaonan Zhang , Xiaomin Fang , Fan Wang , Guodong Zhao

Understanding the dynamic organization and homeostasis of living tissues requires high-resolution, time-resolved imaging coupled with methods capable of extracting interpretable, predictive insights from complex datasets. Here, we present…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Kaan Berke Ugurlar , Joaquín de Navascués , Michael Taynnan Barros

A permanently increasing number of on-board automotive control systems requires new approaches to their digital mapping that improves functionality in terms of adaptability and robustness as well as enables their easier on-line software…

Systems and Control · Electrical Eng. & Systems 2022-07-20 Moritz Zink , Martin Schiele , Valentin Ivanov

In this paper, we propose an Adaptive Neuro-Symbolic Learning and Reasoning Framework for digital twin technology called "ANSR-DT." Digital twins in industrial environments often struggle with interpretability, real-time adaptation, and…

Artificial Intelligence · Computer Science 2025-12-02 Safayat Bin Hakim , Muhammad Adil , Alvaro Velasquez , Houbing Herbert Song

Purpose: CBCT-based adaptive radiotherapy requires daily images for accurate dose calculations. This study investigates the feasibility of applying a single convolutional network to facilitate CBCT-to-CT synthesis for head-and-neck, lung,…

Brain tumor segmentation (BTS) in magnetic resonance image (MRI) is crucial for brain tumor diagnosis, cancer management and research purposes. With the great success of the ten-year BraTS challenges as well as the advances of CNN and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 Jianwei Lin , Jiatai Lin , Cheng Lu , Hao Chen , Huan Lin , Bingchao Zhao , Zhenwei Shi , Bingjiang Qiu , Xipeng Pan , Zeyan Xu , Biao Huang , Changhong Liang , Guoqiang Han , Zaiyi Liu , Chu Han

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…

Quantitative computed tomography (QCT) plays a crucial role in assessing bone strength and fracture risk by enabling volumetric analysis of bone density distribution in the proximal femur. However, deploying automated segmentation models in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Rochak Dhakal , Chen Zhao , Zixin Shi , Joyce H. Keyak , Tadashi S. Kaneko , Kuan-Jui Su , Hui Shen , Hong-Wen Deng , Weihua Zhou

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…