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The shape and connectivity of a neuron determine its function. Modern imaging methods have proven successful at extracting such information. However, in order to analyze this type of data, neuronal morphology needs to be encoded in a…

Neurons and Cognition · Quantitative Biology 2019-03-07 Tamal Batabyal , Barry Condron , Scott T. Acton

Many real-world phenomena are naturally modeled by graphs and networks. However, classical graph models are often limited to pairwise interactions and may not adequately capture the richer structures that arise in practice. Higher-order…

Social and Information Networks · Computer Science 2026-05-18 Takaaki Fujita , Florentin Smarandache

Understanding the mathematical properties of graphs underling biological systems could give hints on the evolutionary mechanisms behind these structures. In this article we perform a complete statistical analysis over thousands of graphs…

Molecular Networks · Quantitative Biology 2019-08-29 D. Gamermann , J. Triana , R. Jaime

A new heuristic based on vertex invariants is developed to rapidly distinguish non-isomorphic graphs to a desired level of accuracy. The method is applied to sample subgraphs from an E.coli protein interaction network, and as a probe for…

Quantitative Methods · Quantitative Biology 2009-11-13 Kim Baskerville , Maya Paczuski

Introduced the quantitative measure of the structural complexity of the graph (complex network, etc.) based on a procedure similar to the renormalization process, considering the difference between actual and averaged graph structures on…

Physics and Society · Physics 2024-06-05 A. A. Snarskii

We present the analysis of the topological graph descriptor Local Degree Profile (LDP), which forms a widely used structural baseline for graph classification. Our study focuses on model evaluation in the context of the recently developed…

Machine Learning · Computer Science 2023-05-02 Jakub Adamczyk , Wojciech Czech

Complex networks describe a wide range of systems in nature and society, much quoted examples including the cell, a network of chemicals linked by chemical reactions, or the Internet, a network of routers and computers connected by physical…

Statistical Mechanics · Physics 2016-08-31 Reka Albert , Albert-Laszlo Barabasi

Large datasets represented by multidimensional data point clouds often possess non-trivial distributions with branching trajectories and excluded regions, with the recent single-cell transcriptomic studies of developing embryo being notable…

We present the spectrum of the (normalized) graph Laplacian as a systematic tool for the investigation of networks, and we describe basic properties of eigenvalues and eigenfunctions. Processes of graph formation like motif joining or…

Adaptation and Self-Organizing Systems · Physics 2012-10-19 Anirban Banerjee , Jürgen Jost

Quantifying the complexity of large graphs requires measures that extend beyond predefined structural features and scale efficiently with graph size. This work adopts a generative perspective, modeling large networks as exchangeable graphs…

Information Theory · Computer Science 2025-03-14 Anda Skeja , Sofia C. Olhede

Graph embeddings have emerged as a powerful tool for representing complex network structures in a low-dimensional space, enabling the use of efficient methods that employ the metric structure in the embedding space as a proxy for the…

Social and Information Networks · Computer Science 2024-04-18 Radosław Nowak , Adam Małkowski , Daniel Cieślak , Piotr Sokół , Paweł Wawrzyński

Objective: The Mapper algorithm is a qualitative method in topological data analysis that constructs graphs from point clouds by combining dimensionality reduction and clustering techniques. The aim of this study is to apply Mapper,…

Quantitative Methods · Quantitative Biology 2026-04-22 Aina Ferrà Marcús , Carles Casacuberta , Josep Vives , Joan Guich , Gerard Amorós-Figueras , Jose M. Guerra

Membrane particles such as proteins and lipids organize into zones that perform unique functions. Here, I introduce a topological and category-theoretic framework to represent particle and zone intra-scale interactions and inter-scale…

Molecular Networks · Quantitative Biology 2026-01-01 Troy A. Kervin

The language of graph theory, or network science, has proven to be an exceptional tool for addressing myriad problems in neuroscience. Yet, the use of networks is predicated on a critical simplifying assumption: that the quintessential unit…

Neurons and Cognition · Quantitative Biology 2016-01-14 Chad Giusti , Robert Ghrist , Danielle S. Bassett

Many real life networks present an average path length logarithmic with the number of nodes and a degree distribution which follows a power law. Often these networks have also a modular and self-similar structure and, in some cases -…

Statistical Mechanics · Physics 2009-02-26 Alicia Miralles , Lichao Chen , Zhongzhi Zhang , Francesc Comellas

Interactions between biomolecules, electrons and protons are essential to many fundamental processes sustaining life. It is therefore of interest to build mathematical models of these bioelectrical processes not only to enhance…

Molecular Networks · Quantitative Biology 2020-12-08 Peter J. Gawthrop , Michael Pan

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

Machine Learning · Computer Science 2024-02-13 Lorenzo Giusti

An isogeny graph is a graph whose vertices are principally polarized abelian varieties and whose edges are isogenies between these varieties. In his thesis, Kohel described the structure of isogeny graphs for elliptic curves and showed that…

Number Theory · Mathematics 2019-02-20 Sorina Ionica , Emmanuel Thomé

The heterogeneity of breast cancer presents considerable challenges for its early detection, prognosis, and treatment selection. Convolutional neural networks often neglect the spatial relationships within histopathological images, which…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Akhila Krishna K , Ravi Kant Gupta , Nikhil Cherian Kurian , Pranav Jeevan , Amit Sethi

Biology presents many examples of planar distribution and structural networks having dense sets of closed loops. An archetype of this form of network organization is the vasculature of dicotyledonous leaves, which showcases a…

Quantitative Methods · Quantitative Biology 2015-05-30 Eleni Katifori , Marcelo O. Magnasco