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Global optimization of crystal compositions is a significant yet computationally intensive method to identify stable structures within chemical space. The specific physical properties linked to a three-dimensional atomic arrangement make…

In this work, we present an efficient framework that combines machine learning potential (MLP) and metadynamics to explore multi-dimensional free energy surfaces for investigating solid-solid phase transition. Based on the spectral…

Materials Science · Physics 2022-11-02 Pedro A. Santos-Florez , Howard Yanxon , Byungkyun Kang , Yansun Yao , Qiang Zhu

Numerical simulations of plasma flows are crucial for advancing our understanding of microscopic processes that drive the global plasma dynamics in fusion devices, space, and astrophysical systems. Identifying and classifying particle…

Computational Physics · Physics 2020-10-13 Stefano Markidis , Ivy Peng , Artur Podobas , Itthinat Jongsuebchoke , Gabriel Bengtsson , Pawel Herman

Most of the current understanding of structure-property relations at the molecular and the supramolecular scales can be formulated in terms of the stability of and the interactions between a limited number of recurring structural motifs…

Chemical Physics · Physics 2018-01-29 Piero Gasparotto , Robert Horst Meißner , Michele Ceriotti

Two-step crystallization via a metastable intermediate phase is often regarded as a non-classical process that lies beyond the framework of classical nucleation theory (CNT). In this work, we investigate two-step crystallization in…

Soft Condensed Matter · Physics 2025-04-10 Willem Gispen , Peter G. Bolhuis , Marjolein Dijkstra

Nucleation phenomena commonly observed in our every day life are of fundamental, technological and societal importance in many areas, but some of their most intimate mechanisms remain however to be unraveled. Crystal nucleation, the early…

Materials Science · Physics 2022-02-09 Sébastien Becker , Emilie Devijver , Rémi Molinier , Noël Jakse

Nucleation is the onset of a first-order phase transition by which a metastable phase transforms into a more stable one. Such a phase transition occurs when an initial system initially in equilibrium is destabilized by the change of an…

Materials Science · Physics 2010-01-27 Emmanuel Clouet

We performed dynamic simulations of spheres with short-range attractive interactions for many values of interaction strength and range. Fast crystallization occurs in a localized region of this parameter space, but the character of…

Soft Condensed Matter · Physics 2015-07-27 Thomas K. Haxton , Lester O. Hedges , Stephen Whitelam

Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror

We use computer simulation to study crystal-forming model proteins equipped with interactions that are both orientationally specific and nonspecific. Distinct dynamical pathways of crystal formation can be selected by tuning the strengths…

Soft Condensed Matter · Physics 2012-04-16 Stephen Whitelam

Accurate structural analysis is essential to gain physical knowledge and understanding of atomic-scale processes in materials from atomistic simulations. However, traditional analysis methods often reach their limits when applied to…

Nucleation is generally viewed as a structural fluctuation that passes a critical size to eventually become a stable emerging new phase. However, this concept leaves out many details, such as changes in cluster composition and competing…

We investigate crystal nucleation in supersaturated colloid suspensions using enhanced molecular dynamics simulations augmented with machine learning techniques. The simulations reveal that crystallization in the model colloidal system…

Soft Condensed Matter · Physics 2024-04-30 Vanessa J. Meraz , Ziyue Zou , Pratyush Tiwary

In studying solidification process by simulations on the atomic scale, the modeling of crystal nucleation or amorphisation requires the construction of interatomic interactions that are able to reproduce the properties of both the solid and…

Based on classical nucleation theory, we propose a couple of theoretical models for the nucleation of polymer crystallization, i.e. one for a single chain system (Model S) and the other for a multi-chain system (Model M). In these models,…

Soft Condensed Matter · Physics 2019-07-05 Hiroshi Yokota , Toshihiro Kawakatsu

Nucleation plays a critical role in the birth of crystals and is associated with a vast array of phenomena such as protein crystallization and ice formation in clouds. Despite numerous experimental and theoretical studies, many aspects of…

Soft Condensed Matter · Physics 2021-08-18 Gabriele M. Coli , Robin van Damme , C. Patrick Royall , Marjolein Dijkstra

Non-aligning self-propelled particles with purely repulsive excluded volume interactions undergo athermal motility-induced phase separation into a dilute gas and a dense cluster phase. Here, we use enhanced sampling computational methods…

Soft Condensed Matter · Physics 2016-10-05 Gabriel S. Redner , Caleb G. Wagner , Aparna Baskaran , Michael F. Hagan

Multi-component metal nanoparticles (NPs) are of paramount importance in the chemical industry, as most processes therein employ heterogeneous catalysts. While these multi-component systems have been shown to result in higher product…

DNA-coated colloids can self-assemble into an incredible diversity of crystal structures, but applications of this technology are limited by poor understanding and control over the dynamical crystallization pathways. To address this…

Soft Condensed Matter · Physics 2021-06-01 Alexander Hensley , William M. Jacobs , W. Benjamin Rogers

We show that it is possible to learn protocols that effect fast and efficient state-to-state transformations in simulation models of active particles. By encoding the protocol in the form of a neural network we use evolutionary methods to…

Statistical Mechanics · Physics 2024-03-29 Corneel Casert , Stephen Whitelam