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Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

Computation and Language · Computer Science 2020-11-21 Mireia Farrús , Joan Codina-Filbà

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power…

Machine Learning · Computer Science 2025-11-11 Richard Hou , Shengpu Tang , Wei Jin

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and delay progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical screening…

Machine Learning · Computer Science 2022-08-09 Yi Wang , Tianzi Wang , Zi Ye , Lingwei Meng , Shoukang Hu , Xixin Wu , Xunying Liu , Helen Meng

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a major cause of dementia. Structural MRI is widely used to analyze AD-related brain atrophy; however, most deep learning methods rely on computationally expensive 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Towhidul Islam , Mufti Mahmud

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Alzheimer's Disease is a devastating neurological disorder that is increasingly affecting the elderly population. Early and accurate detection of Alzheimer's is crucial for providing effective treatment and support for patients and their…

Image and Video Processing · Electrical Eng. & Systems 2023-04-27 Krishna Mahapatra , Selvakumar R

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Hongming Li , Yong Fan

Alzheimer's disease is a human brain disease that affects a significant fraction of the population by causing problems with short-term memory, thinking, spatial orientation and behavior, memory loss and other intellectual abilities. Up to…

Neurons and Cognition · Quantitative Biology 2012-10-02 Athanasios Alexiou , Panayiotis Vlamos

There is a need for automatic diagnosis of certain diseases from medical images that could help medical practitioners for further assessment towards treating the illness. Alzheimers disease is a good example of a disease that is often…

Image and Video Processing · Electrical Eng. & Systems 2019-01-30 GuruRaj Awate

As shown in computer vision, the power of deep learning lies in automatically learning relevant and powerful features for any perdition task, which is made possible through end-to-end architectures. However, deep learning approaches applied…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Soheil Esmaeilzadeh , Dimitrios Ioannis Belivanis , Kilian M. Pohl , Ehsan Adeli

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Early diagnosis of Alzheimer's disease (AD) is essential in preventing the disease's progression. Therefore, detecting AD from neuroimaging data such as structural magnetic resonance imaging (sMRI) has been a topic of intense investigation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Maha M. Alwuthaynani , Zahraa S. Abdallah , Raul Santos-Rodriguez

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the accumulation of amyloid-beta (A$\beta$) and phosphorylated tau (p-tau) proteins, leading to cognitive decline measured by the Alzheimer's Disease…

Neurons and Cognition · Quantitative Biology 2025-04-21 Swadesh Pal , Roderick Melnik

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Over the past decade, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting…

Computer Vision and Pattern Recognition · Computer Science 2016-03-30 Saman Sarraf , Ghassem Tofighi

As the aging of society continues to accelerate, Alzheimer's Disease (AD) has received more and more attention from not only medical but also other fields, such as computer science, over the past decade. Since speech is considered one of…

Robotics · Computer Science 2022-11-17 Yuanchao Li , Catherine Lai , Divesh Lala , Koji Inoue , Tatsuya Kawahara

Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions worldwide. In the absence of effective treatment options, early diagnosis is crucial for initiating management strategies to delay disease onset and slow down…

Machine Learning · Computer Science 2025-07-08 Saeed Jamshidiha , Alireza Rezaee , Farshid Hajati , Mojtaba Golzan , Raymond Chiong
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