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Recent advances in quantum technologies pave the way for noisy intermediate-scale quantum (NISQ) devices, where quantum approximation optimization algorithms (QAOAs) constitute promising candidates for demonstrating tangible quantum…

Information Theory · Computer Science 2021-07-13 Jingjing Cui , Yifeng Xiong , Soon Xin Ng , Lajos Hanzo

Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

Quantum Computing promises to solve complex combinatorial optimization problems more efficiently than classical methods, with the Quantum Approximate Optimization Algorithm (QAOA) being a leading candidate. Recent fixed-parameter variations…

Quantum Physics · Physics 2026-03-04 Rodrigo Coelho , Georg Kruse , Jeanette Miriam Lorenz

Constrained combinatorial optimization problems are challenging for quantum computing, particularly at utility-relevant scales and on near-term hardware. At the same time, these problems are of practical significance in industry; for…

Combinatorial optimization is anticipated to be one of the primary use cases for quantum computation in the coming years. The Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing (QA) can potentially demonstrate…

Quantum computers and simulators may offer significant advantages over their classical counterparts, providing insights into quantum many-body systems and possibly improving performance for solving exponentially hard problems, such as…

The quantum approximate optimization algorithm (QAOA) is a hybrid quantum-classical algorithm for solving combinatorial optimization problems. Multi-angle QAOA (MA-QAOA), which assigns independent parameters to each Hamiltonian operator…

Quantum Approximate Optimization Algorithm (QAOA) enables solving combinatorial optimization problems on quantum computers by optimizing variational parameters for quantum circuits. We investigate a simplified approach that combines linear…

Quantum Physics · Physics 2025-05-26 Ryo Sakai , Hiromichi Matsuyama , Wai-Hong Tam , Yu Yamashiro

Variational quantum algorithms are the centerpiece of modern quantum programming. These algorithms involve training parameterized quantum circuits using a classical co-processor, an approach adapted partly from classical machine learning.…

Quantum Physics · Physics 2022-11-09 V. Akshay , H. Philathong , E. Campos , D. Rabinovich , I. Zacharov , Xiao-Ming Zhang , J. Biamonte

Quantum heuristics offer a potential advantage for combinatorial optimization but are constrained by near-term hardware limitations. We introduce Iterative-QAOA, a variant of QAOA designed to mitigate these constraints. The algorithm…

Quantum algorithms must be scaled up to tackle real-world applications. Doing so requires overcoming the noise present on today's hardware. The quantum approximate optimization algorithm (QAOA) is a promising candidate for scaling up, due…

Quantum Physics · Physics 2026-02-23 Zichang He , David Amaro , Ruslan Shaydulin , Marco Pistoia

The quantum approximate optimization algorithm (QAOA) is an appealing proposal to solve NP problems on noisy intermediate-scale quantum (NISQ) hardware. Making NISQ implementations of the QAOA resilient to noise requires short ansatz…

The Tail Assignment Problem (TAP) is a critical optimization challenge in airline operations, requiring the optimal assignment of aircraft to scheduled flights to maximize efficiency and minimize costs. To address the TAP, this work applies…

Quantum Physics · Physics 2024-12-18 Marta Gili , Paul San Sebastian , Ane Blázquez-García

Many quantum algorithms seek to output a specific bitstring solving the problem of interest--or a few if the solution is degenerate. It is the case for the quantum approximate optimization algorithm (QAOA) in the limit of large circuit…

Quantum Physics · Physics 2022-08-23 Maxime Dupont , Nicolas Didier , Mark J. Hodson , Joel E. Moore , Matthew J. Reagor

The quantum approximate optimization algorithm (QAOA) is a leading variational approach to combinatorial optimization, but its practical performance depends strongly on objective design, parameter search, and shot allocation. We present a…

Quantum Physics · Physics 2026-04-09 Siran Zhang , Shuming Cheng

The Quantum Approximate Optimization Algorithm can naturally be applied to combinatorial search problems on graphs. The quantum circuit has p applications of a unitary operator that respects the locality of the graph. On a graph with…

Quantum Physics · Physics 2020-04-21 Edward Farhi , David Gamarnik , Sam Gutmann

The Vehicle Routing Problem (VRP) is a fundamental combinatorial optimization challenge with broad applications in logistics and transportation. In this work, we present a quantum-assisted framework that integrates the Quantum Approximate…

Quantum Physics · Physics 2026-01-28 Talha Azfar , Osama Muhammad Raisuddin , Ruimin Ke , Jose Holguin-Veras

We develop a qubit routing algorithm with polynomial classical run time for the Quantum Approximate Optimization Algorithm (QAOA). The algorithm follows a two step process. First, it obtains a near-optimal solution, based on Vizing's…

Quantum Physics · Physics 2023-12-27 Ayse Kotil , Fedor Simkovic , Martin Leib

Quantum approximate optimization algorithm (QAOA) has shown promise in solving combinatorial optimization problems by providing quantum speedup on near-term gate-based quantum computing systems. However, QAOA faces challenges for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-24 Seongmin Kim , Vincent R. Pascuzzi , Zhihao Xu , Tengfei Luo , Eungkyu Lee , In-Saeng Suh

Test case optimization (TCO) reduces software testing cost while preserving its effectiveness, but solving TCO problems for large-scale and complex systems requires substantial computational resources. Quantum approximate optimization…

Software Engineering · Computer Science 2026-01-21 Xinyi Wang , Shaukat Ali , Tao Yue , Paolo Arcaini