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The functioning of machines typically requires a concerted action of their parts. This requirement also holds for molecular motors that drive vital cellular processes and imposes constraints on their conformational changes as well as the…

Biological Physics · Physics 2022-06-14 Zena Hadjivasiliou , Karsten Kruse

Soil is a complex, dynamic material, with physical properties that depend on its biological content. We propose a cellular automaton model for self-organizing soil structure, where soil aggregates and serves as food for microbial species.…

Biological Physics · Physics 2025-10-10 Riz Fernando Noronha , Kim Sneppen , Kunihiko Kaneko

We present a simple model based on a reaction-diffusion equation to explain pattern formation in a multicellular bacterium (Streptomyces). We assume competition for resources as the basic mechanism that leads to pattern formation; in…

Biological Physics · Physics 2007-05-23 M. Bezzi , A. Ciliberto , A. Mengoni

As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as in…

Cell Behavior · Quantitative Biology 2017-02-08 Jumpei F Yamagishi , Nen Saito , Kunihiko Kaneko

The problem of natural selection in dispersal-structured populations consisting of individuals characterized by different diffusion coefficients is studied. The competition between the organisms is taken into account through the assumption…

Adaptation and Self-Organizing Systems · Physics 2020-05-01 E. Heinsalu , D. Navidad Maeso , M. Patriarca

Quorum sensing is a decentralized biological process, through which a community of cells with no global awareness coordinate their functional behaviors based solely on cell-medium interactions and local decisions. This paper draws…

Machine Learning · Computer Science 2015-10-08 Feng Tan , Jean-Jacques Slotine

Predictive modeling is the key factor for saving time and resources with respect to manufacturing processes such as fermentation processes arising e.g.\ in food and chemical manufacturing processes. According to Zhang et al. (2002), the…

Analysis of PDEs · Mathematics 2021-04-15 Christina Schenk , Volker H. Schulz

By generalizing a class of models recently introduced to account for protracted transients in biological systems, we identify a novel mechanism for hyperuniformity. In this model, competition of particles over a shared resource guides the…

Statistical Mechanics · Physics 2025-12-11 Tal Agranov , Natan Wiegenfeld , Omer Karin , Benjamin D. Simons

We present a simple mathematical model that captures the evolutionary capabilities of a prebiotic compartment or protocell. In the model the protocell contains an autocatalytic set whose chemical dynamics is coupled to the growth-division…

Populations and Evolution · Quantitative Biology 2023-10-31 Angad Yuvraj Singh , Sanjay Jain

Non-traditional thermodynamics, applied to random behaviour associated with turbulence, mixing and competition, is reviewed and analysed. Competitive mixing represents a general framework for the study of generic properties of competitive…

Adaptation and Self-Organizing Systems · Physics 2013-05-08 A. Y. Klimenko

We investigate extinction dynamics in the paradigmatic model of two competing species A and B that reproduce (A-->2A, B-->2B), self-regulate by annihilation (2A-->0, 2B-->0), and compete (A+B-->A, A+B-->B). For a finite system that is in…

Statistical Mechanics · Physics 2014-08-06 Alan Gabel , Baruch Meerson , S. Redner

Genetic information and environmental factors determine the path of an individuals life and therefore, the evolution of its entire species. We have succeeded in proposing and studying a model that captures this idea. In our model, a…

Populations and Evolution · Quantitative Biology 2021-07-28 N. Abadi , G. Abramson

We present a simple discrete model for the non-linear spatial interaction of different kinds of ``subpopulations'' composed of identical moving entities like particles, bacteria, individuals, etc. The model allows to mimic a variety of…

Statistical Mechanics · Physics 2007-05-23 Dirk Helbing , Tadeusz Platkowski

Micro-organisms aggregate through chemotaxis against a concentration gradient of signals secreted by themselves. We have numerically studied a model consisting of elements with intracellular dynamics, random walks with a state-dependent…

Statistical Mechanics · Physics 2007-10-31 Masayo Inoue , Kunihiko Kaneko

Microbial communities routinely have several possible species compositions or community states observed for the same environmental parameters. Changes in these parameters can trigger abrupt and persistent transitions (regime shifts) between…

Populations and Evolution · Quantitative Biology 2019-07-03 Veronika Dubinkina , Yulia Fridman , Parth Pratim Pandey , Sergei Maslov

A fundamental problem in protobiological dynamics is to understand how chemically generated polymers can form persistent sequence distributions before the emergence of replication. We study deterministic polymer growth in which each finite…

Populations and Evolution · Quantitative Biology 2026-05-06 J. Medina Diaz , F. Peña-Garcia , Irbin Llanqui

Cell competition is a quality control mechanism in tissues that results in the elimination of less fit cells. Over the past decade, the phenomenon of cell competition has been identified in many physiological and pathological contexts,…

Tissues and Organs · Quantitative Biology 2019-03-26 Daniel Gradeci , Anna Bove , Guillaume Charras , Alan R. Lowe , Shiladitya Banerjee

We deal with strongly competing multispecies systems of Lotka-Volterra type with homogeneous Neumann boundary conditions in dumbbell-like domains. Under suitable non-degeneracy assumptions, we show that, as the competition rate grows…

Analysis of PDEs · Mathematics 2008-12-15 Monica Conti , Veronica Felli

Autocatalysis is a deceptively simple concept, referring to the situation that a chemical species $X$ catalyzes its own formation. From the perspective of chemical kinetics, autocatalysts show a regime of super-linear growth. Given a…

Molecular Networks · Quantitative Biology 2021-07-08 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

Cells coexist together in colonies or as tissues. Their behaviour is controlled by an interplay between intercellular forces and biochemical regulation. We develop a simple model of the cell cycle, the fundamental regulatory network…

Biological Physics · Physics 2021-08-04 Jintao Li , Simon K. Schnyder , Matthew S. Turner , Ryoichi Yamamoto