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The versatility of multimodal deep learning holds tremendous promise for advancing scientific research and practical applications. As this field continues to evolve, the collective power of cross-modal analysis promises to drive…

Machine Learning · Computer Science 2025-05-15 Yifei Wang , Yunrui Li , Lin Liu , Pengyu Hong , Hao Xu

Large Language Models (LLMs) stand at the forefront of a number of Natural Language Processing (NLP) tasks. Despite the widespread adoption of LLMs in NLP, much of their potential in broader fields remains largely unexplored, and…

Machine Learning · Computer Science 2024-03-11 Zhiqiang Zhong , Kuangyu Zhou , Davide Mottin

Large pre-trained language models have demonstrated their proficiency in storing factual knowledge within their parameters and achieving remarkable results when fine-tuned for downstream natural language processing tasks. Nonetheless, their…

Computation and Language · Computer Science 2023-09-29 Konstantinos Andriopoulos , Johan Pouwelse

The prevailing approach to aligning Large Language Models (LLMs) typically relies on human or AI feedback and assumes access to specific types of preference datasets. In our work, we question the efficacy of such datasets and explore…

Machine Learning · Computer Science 2024-03-19 Hao Sun

Large language models (LLMs) are beginning to reshape how chemists plan and run reactions in organic synthesis. Trained on millions of reported transformations, these text-based models can propose synthetic routes, forecast reaction…

Artificial Intelligence · Computer Science 2025-08-08 Kartar Kumar Lohana Tharwani , Rajesh Kumar , Sumita , Numan Ahmed , Yong Tang

Large language models (LLMs) have demonstrated their instruction-following capabilities and achieved powerful performance on various tasks. Inspired by their success, recent works in the molecular domain have led to the development of large…

Artificial Intelligence · Computer Science 2026-01-21 Jinyoung Park , Minseong Bae , Jeehye Na , Hyunwoo J. Kim

Large Language Models (LLMs) have shown remarkable performance across a wide range of natural language processing tasks. Quality Estimation (QE) for Machine Translation (MT), which assesses the quality of a source-target pair without…

Computation and Language · Computer Science 2025-08-12 Archchana Sindhujan , Shenbin Qian , Chan Chi Chun Matthew , Constantin Orasan , Diptesh Kanojia

The rapid development of Large Language Models (LLMs) has significantly enhanced the general capabilities of machine translation. However, as application scenarios become more complex, the limitations of LLMs in vertical domain translations…

Computation and Language · Computer Science 2026-02-03 Chaoqun Cui , Shijing Wang , Liangbin Huang , Qingqing Gu , Zhaolong Huang , Xiao Zeng , Wenji Mao

Learning from preference labels plays a crucial role in fine-tuning large language models. There are several distinct approaches for preference fine-tuning, including supervised learning, on-policy reinforcement learning (RL), and…

Although large language models (LLMs) perform well in general tasks, domain-specific applications suffer from hallucinations and accuracy limitations. Continual Pre-Training (CPT) approaches encounter two key issues: (1) domain-biased data…

Computation and Language · Computer Science 2025-05-21 Jingxue Chen , Qingkun Tang , Qianchun Lu , Siyuan Fang

Open-sourced large language models (LLMs) have demonstrated remarkable efficacy in various tasks with instruction tuning. However, these models can sometimes struggle with tasks that require more specialized knowledge such as translation.…

Computation and Language · Computer Science 2024-01-23 Jiali Zeng , Fandong Meng , Yongjing Yin , Jie Zhou

Large language models (LLMs) have significantly advanced various natural language processing (NLP) tasks. Recent research indicates that moderately-sized LLMs often outperform larger ones after task-specific fine-tuning. This study focuses…

Computation and Language · Computer Science 2024-10-14 Minghao Wu , Thuy-Trang Vu , Lizhen Qu , George Foster , Gholamreza Haffari

Pretrained language models (PLMs) display impressive performances and have captured the attention of the NLP community. Establishing best practices in pretraining has, therefore, become a major focus of NLP research, especially since…

Computation and Language · Computer Science 2024-10-08 Zihao Li , Shaoxiong Ji , Timothee Mickus , Vincent Segonne , Jörg Tiedemann

Large language models (LLMs) have emerged as powerful tools in chemistry, significantly impacting molecule design, property prediction, and synthesis optimization. This review highlights LLM capabilities in these domains and their potential…

Machine Learning · Computer Science 2024-11-18 Mayk Caldas Ramos , Christopher J. Collison , Andrew D. White

Uncertainty estimation is a necessary component when implementing AI in high-risk settings, such as autonomous cars, medicine, or insurances. Large Language Models (LLMs) have seen a surge in popularity in recent years, but they are subject…

Machine Learning · Computer Science 2024-12-09 Gabriel Y. Arteaga , Thomas B. Schön , Nicolas Pielawski

Large Language Models (LLMs) have demonstrated exceptional performance in biochemical tasks, especially the molecule caption translation task, which aims to bridge the gap between molecules and natural language texts. However, previous…

Computation and Language · Computer Science 2025-04-08 Jiatong Li , Wei Liu , Zhihao Ding , Wenqi Fan , Yuqiang Li , Qing Li

Large Language Models (LLMs) with their strong task-handling capabilities have shown remarkable advancements across a spectrum of fields, moving beyond natural language understanding. However, their proficiency within the chemistry domain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Khiem Le , Zhichun Guo , Kaiwen Dong , Xiaobao Huang , Bozhao Nan , Roshni Iyer , Xiangliang Zhang , Olaf Wiest , Wei Wang , Ting Hua , Nitesh V. Chawla

This article introduces contrastive alignment instructions (AlignInstruct) to address two challenges in machine translation (MT) on large language models (LLMs). One is the expansion of supported languages to previously unseen ones. The…

Computation and Language · Computer Science 2024-07-23 Zhuoyuan Mao , Yen Yu

Artificial intelligence (AI) tools such as large language models (LLMs) are already altering student learning. Unlike previous technologies, LLMs can independently solve problems regardless of student understanding, yet are not always…

Theoretical Economics · Economics 2025-09-04 Eric Gao

Large language model (LLM) shows promising performances in a variety of downstream tasks, such as machine translation (MT). However, using LLMs for translation suffers from high computational costs and significant latency. Based on our…

Computation and Language · Computer Science 2025-05-21 Zhanglin Wu , Daimeng Wei , Xiaoyu Chen , Hengchao Shang , Jiaxin Guo , Zongyao Li , Yuanchang Luo , Jinlong Yang , Zhiqiang Rao , Hao Yang