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This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan

Retrieval-augmented generation enhances large language models (LLMs) by incorporating relevant information from external knowledge sources. This enables LLMs to adapt to specific domains and mitigate hallucinations in knowledge-intensive…

Computation and Language · Computer Science 2024-06-05 Lingxi Zhang , Yue Yu , Kuan Wang , Chao Zhang

Large Language Models (LLMs) pre-trained on internet-scale datasets have shown impressive capabilities in code understanding, synthesis, and general purpose question-and-answering. Key to their performance is the substantial prior knowledge…

Robotics · Computer Science 2023-11-03 Andrea Tagliabue , Kota Kondo , Tong Zhao , Mason Peterson , Claudius T. Tewari , Jonathan P. How

Recent advances in large language models (LLMs) have made significant progress across multiple biomedical tasks, including biomedical question answering, lay-language summarization of the biomedical literature, and clinical note…

Information Retrieval · Computer Science 2026-03-24 Deepak Gupta , Dina Demner-Fushman , William Hersh , Steven Bedrick , Kirk Roberts

Open-domain semantic parsing remains a challenging task, as neural models often rely on heuristics and struggle to handle unseen concepts. In this paper, we investigate the potential of large language models (LLMs) for this task and…

Computation and Language · Computer Science 2025-08-21 Xiao Zhang , Qianru Meng , Johan Bos

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

The integration of Large Language Models (LLMs) into the public health policy sector offers a transformative approach to navigating the vast repositories of regulatory guidance maintained by agencies such as the Centers for Disease Control…

Computation and Language · Computer Science 2026-01-23 Anuj Maharjan , Umesh Yadav

Large Language Models (LLMs) excel at reasoning and generation but are inherently limited by static pretraining data, resulting in factual inaccuracies and weak adaptability to new information. Retrieval-Augmented Generation (RAG) addresses…

Computation and Language · Computer Science 2025-11-03 Qi Luo , Xiaonan Li , Yuxin Wang , Tingshuo Fan , Yuan Li , Xinchi Chen , Xipeng Qiu

Current vision-language models (VLMs) still exhibit inferior performance on knowledge-intensive tasks, primarily due to the challenge of accurately encoding all the associations between visual objects and scenes to their corresponding…

Computation and Language · Computer Science 2024-10-16 Jingyuan Qi , Zhiyang Xu , Rulin Shao , Yang Chen , Jin Di , Yu Cheng , Qifan Wang , Lifu Huang

Large Language Models (LLMs) are the cornerstone in automating Requirements Engineering (RE) tasks, underpinning recent advancements in the field. Their pre-trained comprehension of natural language is pivotal for effectively tailoring them…

Software Engineering · Computer Science 2024-05-16 Andreas Vogelsang , Jannik Fischbach

Large language models (LLMs) have demonstrated impressive capabilities across diverse languages. This study explores how LLMs handle multilingualism. Based on observed language ratio shifts among layers and the relationships between network…

Computation and Language · Computer Science 2024-11-12 Yiran Zhao , Wenxuan Zhang , Guizhen Chen , Kenji Kawaguchi , Lidong Bing

The increasing use of large language models (LLMs) in causal discovery as a substitute for human domain experts highlights the need for optimal model selection. This paper presents the first hallucination survey of popular LLMs for causal…

Computation and Language · Computer Science 2024-11-21 Grace Sng , Yanming Zhang , Klaus Mueller

Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

Retrieval-Augmented Generation (RAG) offers a well-established path to grounding large language model (LLM) outputs in external knowledge, yet the question of which retrieval strategy works best in a high-stakes domain such as biomedicine…

Computation and Language · Computer Science 2026-05-05 Devi Prasad Bal , Subhashree Puhan

While large language models (LLMs) have demonstrated remarkable versatility across a wide range of general tasks, their effectiveness often diminishes in domain-specific applications due to inherent knowledge gaps. Moreover, their…

Artificial Intelligence · Computer Science 2025-11-21 Hanzhi Yan , Qin Lu , Xianqiao Wang , Xiaoming Zhai , Tianming Liu , He Li

Retrieval-augmented generation (RAG) systems combine large language models (LLMs) with external knowledge retrieval, making them highly effective for knowledge-intensive tasks. A crucial but often under-explored component of these systems…

Computation and Language · Computer Science 2025-05-19 Jiashuo Sun , Xianrui Zhong , Sizhe Zhou , Jiawei Han

This research paper discusses the advances made in the past decade in biomedicine and Large Language Models. To understand how the advances have been made hand-in-hand with one another, the paper also discusses the integration of Natural…

Computation and Language · Computer Science 2024-06-26 Michael Ackerman

Hallucinations present a significant challenge for large language models (LLMs). The utilization of parametric knowledge in generating factual content is constrained by the limited knowledge of LLMs, potentially resulting in internal…

Computation and Language · Computer Science 2025-10-07 Hanxing Ding , Liang Pang , Zihao Wei , Huawei Shen , Xueqi Cheng

The significant advancements in Large Language Models (LLMs) have resulted in their widespread adoption across various tasks within Software Engineering (SE), including vulnerability detection and repair. Numerous studies have investigated…

Software Engineering · Computer Science 2024-10-08 Xin Zhou , Sicong Cao , Xiaobing Sun , David Lo