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The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Recent development in Retrieval-Augmented Large Language Models (LLMs) have shown great promise in biomedical applications. How ever, a critical gap persists in reliably evaluating their curation ability the process by which models select…

Computation and Language · Computer Science 2025-08-07 Hanmeng Zhong , Linqing Chen , Wentao Wu , Weilei Wang

Large language models (LLMs) have achieved strong empirical performance in various fields, benefiting from their huge amount of parameters that store knowledge. However, LLMs still suffer from several key issues, such as hallucination…

Computation and Language · Computer Science 2026-05-20 Shangyu Wu , Ying Xiong , Yufei Cui , Haolun Wu , Can Chen , Ye Yuan , Lianming Huang , Xue Liu , Tei-Wei Kuo , Nan Guan , Chun Jason Xue

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

Computation and Language · Computer Science 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

Retrieval Augmented Language Models (RALMs) have gained significant attention for their ability to generate accurate answer and improve efficiency. However, RALMs are inherently vulnerable to imperfect information due to their reliance on…

Computation and Language · Computer Science 2024-10-22 Seong-Il Park , Jay-Yoon Lee

Large language models have achieved remarkable success on general NLP tasks, but they may fall short for domain-specific problems. Recently, various Retrieval-Augmented Large Language Models (RALLMs) are proposed to address this…

Computation and Language · Computer Science 2024-06-18 Shangqing Tu , Yuanchun Wang , Jifan Yu , Yuyang Xie , Yaran Shi , Xiaozhi Wang , Jing Zhang , Lei Hou , Juanzi Li

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

As one of the most advanced techniques in AI, Retrieval-Augmented Generation (RAG) can offer reliable and up-to-date external knowledge, providing huge convenience for numerous tasks. Particularly in the era of AI-Generated Content (AIGC),…

Computation and Language · Computer Science 2024-06-18 Wenqi Fan , Yujuan Ding , Liangbo Ning , Shijie Wang , Hengyun Li , Dawei Yin , Tat-Seng Chua , Qing Li

Large language models (LLMs) have shown remarkable achievements in natural language processing tasks, producing high-quality outputs. However, LLMs still exhibit limitations, including the generation of factually incorrect information. In…

Computation and Language · Computer Science 2023-11-17 Sridevi Wagle , Sai Munikoti , Anurag Acharya , Sara Smith , Sameera Horawalavithana

Large language models (LLMs) augmented with external data have demonstrated remarkable capabilities in completing real-world tasks. Techniques for integrating external data into LLMs, such as Retrieval-Augmented Generation (RAG) and…

Computation and Language · Computer Science 2024-09-24 Siyun Zhao , Yuqing Yang , Zilong Wang , Zhiyuan He , Luna K. Qiu , Lili Qiu

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

The emergence of large language models (LLMs) has revolutionized machine learning and related fields, showcasing remarkable abilities in comprehending, generating, and manipulating human language. However, their conventional usage through…

Computation and Language · Computer Science 2024-04-18 Andrea Bacciu , Florin Cuconasu , Federico Siciliano , Fabrizio Silvestri , Nicola Tonellotto , Giovanni Trappolini

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Despite the remarkable ability of large vision-language models (LVLMs) in image comprehension, these models frequently generate plausible yet factually incorrect responses, a phenomenon known as hallucination.Recently, in large language…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Xiaoye Qu , Qiyuan Chen , Wei Wei , Jishuo Sun , Jianfeng Dong

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Large Language Models (LLMs) show potential for medical applications but often lack specialized clinical knowledge. Retrieval Augmented Generation (RAG) allows customization with domain-specific information, making it suitable for…

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Objective: To demonstrate the capabilities of Large Language Models (LLMs) as autonomous agents to reproduce findings of published research studies using the same or similar dataset. Materials and Methods: We used the "Quick Access" dataset…

Computation and Language · Computer Science 2025-06-02 Nic Dobbins , Christelle Xiong , Kristine Lan , Meliha Yetisgen

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

Large Language Models (LLMs) demonstrate human-level capabilities in dialogue, reasoning, and knowledge retention. However, even the most advanced LLMs face challenges such as hallucinations and real-time updating of their knowledge.…

Computation and Language · Computer Science 2024-09-10 Xuanwang Zhang , Yunze Song , Yidong Wang , Shuyun Tang , Xinfeng Li , Zhengran Zeng , Zhen Wu , Wei Ye , Wenyuan Xu , Yue Zhang , Xinyu Dai , Shikun Zhang , Qingsong Wen