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MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

A medical AI system's generalizability describes the continuity of its performance acquired from varying geographic, historical, and methodologic settings. Previous literature on this topic has mostly focused on "how" to achieve high…

Image and Video Processing · Electrical Eng. & Systems 2022-12-19 Engin Dikici , Xuan Nguyen , Noah Takacs , Luciano M. Prevedello

Medical Image Analysis (MedIA) has emerged as a crucial tool in computer-aided diagnosis systems, particularly with the advancement of deep learning (DL) in recent years. However, well-trained deep models often experience significant…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Ziwei Niu , Shuyi Ouyang , Shiao Xie , Yen-wei Chen , Lanfen Lin

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text…

Machine Learning · Computer Science 2025-12-12 Haolin Li , Tianjie Dai , Zhe Chen , Siyuan Du , Jiangchao Yao , Ya Zhang , Yanfeng Wang

The integration of deep learning based systems in clinical practice is often impeded by challenges rooted in limited and heterogeneous medical datasets. In addition, the field has increasingly prioritized marginal performance gains on a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Sebastian Doerrich , Francesco Di Salvo , Julius Brockmann , Christian Ledig

Multimodal large models have shown great potential in automating pathology image analysis. However, current multimodal models for gastrointestinal pathology are constrained by both data quality and reasoning transparency: pervasive noise…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Minxi Ouyang , Lianghui Zhu , Yaqing Bao , Qiang Huang , Jingli Ouyang , Tian Guan , Xitong Ling , Jiawen Li , Song Duan , Wenbin Dai , Li Zheng , Xuemei Zhang , Yonghong He

Modern deep learning methods have achieved impressive results across tasks from disease classification, estimating continuous biomarkers, to generating realistic medical images. Most of these approaches are trained to model conditional…

Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance. In this…

Machine Learning · Computer Science 2025-04-29 Haroui Ma , Francesco Quinzan , Theresa Willem , Stefan Bauer

Medical image analysis (MedIA) has become an essential tool in medicine and healthcare, aiding in disease diagnosis, prognosis, and treatment planning, and recent successes in deep learning (DL) have made significant contributions to its…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Jee Seok Yoon , Kwanseok Oh , Yooseung Shin , Maciej A. Mazurowski , Heung-Il Suk

Rapid advances in medical imaging technology underscore the critical need for precise and automated image quality assessment (IQA) to ensure diagnostic accuracy. Existing medical IQA methods, however, struggle to generalize across diverse…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Siyi Xun , Yue Sun , Jingkun Chen , Zitong Yu , Tong Tong , Xiaohong Liu , Mingxiang Wu , Tao Tan

Magnetic Resonance Imaging (MRI) is indispensable in clinical practice but remains constrained by fragmented, multi-stage workflows encompassing acquisition, reconstruction, segmentation, detection, diagnosis, and reporting. While deep…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xingxin He , Aurora Rofena , Ruimin Feng , Haozhe Liao , Zhaoye Zhou , Albert Jang , Fang Liu

Vision-language foundation models achieve promising performance in natural image classification, yet their direct application to medical imaging is limited by severe domain shifts, resolution mismatches, and the multi-label nature of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yitong Li , Morteza Ghahremani , Christian Wachinger

Medical generative models, acknowledged for their high-quality sample generation ability, have accelerated the fast growth of medical applications. However, recent works concentrate on separate medical generation models for distinct medical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-08 Chenlu Zhan , Yu Lin , Gaoang Wang , Hongwei Wang , Jian Wu

Non-rigid registration is a necessary but challenging task in medical imaging studies. Recently, unsupervised registration models have shown good performance, but they often require a large-scale training dataset and long training times.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-22 Heejung Park , Gyeong Min Lee , Soopil Kim , Ga Hyung Ryu , Areum Jeong , Sang Hyun Park , Min Sagong

Vision-Language Models (VLMs) trained on web-scale corpora excel at natural image tasks and are increasingly repurposed for healthcare; however, their competence in medical tasks remains underexplored. We present a comprehensive evaluation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Che Liu , Jiazhen Pan , Weixiang Shen , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

In this paper, we examine the recent Segment Anything Model (SAM) on medical images, and report both quantitative and qualitative zero-shot segmentation results on nine medical image segmentation benchmarks, covering various imaging…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Peilun Shi , Jianing Qiu , Sai Mu Dalike Abaxi , Hao Wei , Frank P. -W. Lo , Wu Yuan

Estimating average human performance has been performed inconsistently in research in diagnostic medicine. This has been particularly apparent in the field of medical artificial intelligence, where humans are often compared against AI…

Methodology · Statistics 2020-09-28 Luke Oakden-Rayner , Lyle Palmer

Biomedical image analysis is fundamental for biomedical discovery in cell biology, pathology, radiology, and many other biomedical domains. Holistic image analysis comprises interdependent subtasks such as segmentation, detection, and…

Medical Visual Question Answering (MedVQA) presents a significant opportunity to enhance diagnostic accuracy and healthcare delivery by leveraging artificial intelligence to interpret and answer questions based on medical images. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Xiaoman Zhang , Chaoyi Wu , Ziheng Zhao , Weixiong Lin , Ya Zhang , Yanfeng Wang , Weidi Xie

Continuous Medical Education (CME) plays a vital role in physicians' ongoing professional development. Beyond immediate diagnoses, physicians utilize multimodal diagnostic data for retrospective learning, engaging in self-directed analysis…

Human-Computer Interaction · Computer Science 2024-11-26 Yuansong Xu , Jiahe Dong , Yijie Fan , Yuheng Shao , Chang Jiang , Lixia Jin , Yuanwu Cao , Quan Li