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Non-negative matrix factorization (NMF) is a fundamental matrix decomposition technique that is used primarily for dimensionality reduction and is increasing in popularity in the biological domain. Although finding a unique NMF is generally…

Information Theory · Computer Science 2021-08-23 Rami Nasser , Yonina C. Eldar , Roded Sharan

Non-negative Matrix Factorization (NMF) is an intensively used technique for obtaining parts-based, lower dimensional and non-negative representation. Researchers in biology, medicine, pharmacy and other fields often prefer NMF over other…

Machine Learning · Computer Science 2025-02-04 Matej Mihelčić , Pauli Miettinen

The spectrum of mutations in a collection of cancer genomes can be described by a mixture of a few mutational signatures. The mutational signatures can be found using non-negative matrix factorization (NMF). To extract the mutational…

Methodology · Statistics 2022-11-02 Marta Pelizzola , Ragnhild Laursen , Asger Hobolth

Mutational signature analysis has emerged as a powerful method for uncovering the underlying biological processes driving cancer development. However, the signature extraction process, typically performed using non-negative matrix…

Applications · Statistics 2026-02-27 Ida Egendal , Rasmus Froberg Brøndum , Dan J Woodcock , Christopher Yau , Martin Bøgsted

Nonnegative matrix factorization (NMF) has become a widely used tool for the analysis of high-dimensional data as it automatically extracts sparse and meaningful features from a set of nonnegative data vectors. We first illustrate this…

Machine Learning · Statistics 2014-12-10 Nicolas Gillis

Non-negative matrix factorization (NMF) has become a popular method for representing meaningful data by extracting a non-negative basis feature from an observed non-negative data matrix. Some of the unique features of this method in…

Optimization and Control · Mathematics 2022-11-15 Sajad Fathi Hafshejani , Zahra Moaberfard

Nonnegative Matrix Factorization (NMF) is the problem of approximating a nonnegative matrix with the product of two low-rank nonnegative matrices and has been shown to be particularly useful in many applications, e.g., in text mining, image…

Optimization and Control · Mathematics 2012-08-13 Nicolas Gillis , François Glineur

Nonnegative matrix factorization (NMF) is a popular model in the field of pattern recognition. It aims to find a low rank approximation for nonnegative data M by a product of two nonnegative matrices W and H. In general, NMF is NP-hard to…

Machine Learning · Computer Science 2021-09-07 Junjun Pan , Michael K. Ng

Non-negative matrix factorization (NMF) is one of the most popular decomposition techniques for multivariate data. NMF is a core method for many machine-learning related computational problems, such as data compression, feature extraction,…

Numerical Analysis · Computer Science 2017-12-07 Gabriele Torre , Michael Graber

In this paper we explore avenues for improving the reliability of dimensionality reduction methods such as Non-Negative Matrix Factorization (NMF) as interpretive exploratory data analysis tools. We first explore the difficulties of the…

Artificial Intelligence · Computer Science 2009-04-22 Nikolaos Vasiloglou , Alexander G. Gray , David V. Anderson

Non-negative matrix factorisation (NMF) is a widely used tool for unsupervised learning and feature extraction, with applications ranging from genomics to text analysis and signal processing. Standard formulations of NMF are typically…

Machine Learning · Computer Science 2026-03-11 Elisabeth Sommer James , Asger Hobolth , Marta Pelizzola

Nonnegative matrix factorization (NMF) has become a workhorse for signal and data analytics, triggered by its model parsimony and interpretability. Perhaps a bit surprisingly, the understanding to its model identifiability---the major…

Signal Processing · Electrical Eng. & Systems 2019-03-27 Xiao Fu , Kejun Huang , Nicholas D. Sidiropoulos , Wing-Kin Ma

Non-negative Matrix Factorization (NMF) is one of the most popular techniques for data representation and clustering, and has been widely used in machine learning and data analysis. NMF concentrates the features of each sample into a…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Mulin Chen , Maoguo Gong , Xuelong Li

Non-negative matrix factorization (NMF) and non-negative tensor factorization (NTF) decompose non-negative high-dimensional data into non-negative low-rank components. NMF and NTF methods are popular for their intrinsic interpretability and…

Machine Learning · Computer Science 2024-12-02 Alexander Sietsema , Zerrin Vural , James Chapman , Yotam Yaniv , Deanna Needell

In this paper we consider the Nonnegative Matrix Factorization (NMF) problem: given an (elementwise) nonnegative matrix $V \in \R_+^{m\times n}$ find, for assigned $k$, nonnegative matrices $W\in\R_+^{m\times k}$ and $H\in\R_+^{k\times n}$…

Optimization and Control · Mathematics 2007-05-23 Lorenzo Finesso , Peter Spreij

Nonnegative matrix factorization (NMF) is a widely used tool for learning parts-based, low-dimensional representations of nonnegative data, with applications in vision, text, and bioinformatics. In clustering applications, orthogonal NMF…

Machine Learning · Computer Science 2025-12-10 Manh Nguyen , Daniel Pimentel-Alarcón

Dimensionality reduction is considered as an important step for ensuring competitive performance in unsupervised learning such as anomaly detection. Non-negative matrix factorization (NMF) is a popular and widely used method to accomplish…

Machine Learning · Computer Science 2021-02-08 Imtiaz Ahmed , Xia Ben Hu , Mithun P. Acharya , Yu Ding

In this paper, we introduce and provide a short overview of nonnegative matrix factorization (NMF). Several aspects of NMF are discussed, namely, the application in hyperspectral imaging, geometry and uniqueness of NMF solutions,…

Numerical Analysis · Computer Science 2017-03-03 Nicolas Gillis

Non-negative Matrix Factorization (NMF) is a powerful technique for analyzing regularly-sampled data, i.e., data that can be stored in a matrix. For audio, this has led to numerous applications using time-frequency (TF) representations like…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-10 Krishna Subramani , Paris Smaragdis , Takuya Higuchi , Mehrez Souden

We show how to incorporate information from labeled examples into nonnegative matrix factorization (NMF), a popular unsupervised learning algorithm for dimensionality reduction. In addition to mapping the data into a space of lower…

Machine Learning · Computer Science 2011-12-19 Youngmin Cho , Lawrence K. Saul
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