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The linking of clinical entities is a crucial part of extracting structured information from clinical texts. It is the process of assigning a code from a medical ontology or classification to a phrase in the text. The International…

Computation and Language · Computer Science 2025-09-08 Sylvia Vassileva , Ivan Koychev , Svetla Boytcheva

Recent advances in large language models (LLMs) show potential for clinical applications, such as clinical decision support and trial recommendations. However, the GPT-4 LLM predicts an excessive number of ICD codes for medical coding…

Computation and Language · Computer Science 2023-11-27 Zhichao Yang , Sanjit Singh Batra , Joel Stremmel , Eran Halperin

Background: Medical coding structures healthcare data for research, quality monitoring, and policy. This study assesses the potential of large language models (LLMs) to assign ICPC-2 codes using the output of a domain-specific search…

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

Computation and Language · Computer Science 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Large Language Models (LLMs) have become a pivotal research area, potentially making beneficial contributions in fields like healthcare where they can streamline automated billing and decision support. However, the frequent use of…

Computation and Language · Computer Science 2024-06-10 Simon A. Lee , Timothy Lindsey

General purpose Large Language Models (LLM) such as the Generative Pretrained Transformer (GPT) and Large Language Model Meta AI (LLaMA) have attracted much attention in recent years. There is strong evidence that these models can perform…

Computation and Language · Computer Science 2024-04-25 Hossein Salami , Brandye Smith-Goettler , Vijay Yadav

Metadata play a crucial role in ensuring the findability, accessibility, interoperability, and reusability of datasets. This paper investigates the potential of large language models (LLMs), specifically GPT-4, to improve adherence to…

Artificial Intelligence · Computer Science 2025-02-24 Sowmya S. Sundaram , Benjamin Solomon , Avani Khatri , Anisha Laumas , Purvesh Khatri , Mark A. Musen

This study presents a novel two-stage Retrieve-Rank system for automated ICD-10-CM medical coding, comparing its performance against a Vanilla Large Language Model (LLM) approach. Evaluating both systems on a dataset of 100 single-term…

Information Retrieval · Computer Science 2024-07-19 Keith Kwan

Improving the accuracy and reliability of medical coding reduces clinician burnout and supports revenue cycle processes, freeing providers to focus more on patient care. However, automating the assignment of ICD-10-CM and CPT codes from…

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

Mental health has become a global priority, leading to a massive administrative burden in the coding of clinical diagnoses. This study proposes the automation of psychiatric diagnostic analysis by mapping free-text descriptions to the…

This paper introduces an approach that combines the language reasoning capabilities of large language models (LLMs) with the benefits of local training to tackle complex, domain-specific tasks. Specifically, the authors demonstrate their…

Computation and Language · Computer Science 2023-08-04 V. K. Cody Bumgardner , Aaron Mullen , Sam Armstrong , Caylin Hickey , Jeff Talbert

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan

Although large language models (LLMs) often produce impressive outputs, it remains unclear how they perform in real-world scenarios requiring strong reasoning skills and expert domain knowledge. We set out to investigate whether close- and…

Computation and Language · Computer Science 2023-12-27 Valentin Liévin , Christoffer Egeberg Hother , Andreas Geert Motzfeldt , Ole Winther

LLMs are increasingly explored for malware analysis; however, current LLM-based malware attribution remains limited by unsupported indicators and insufficient code-level grounding for identifying malicious and vulnerable code segments. To…

Cryptography and Security · Computer Science 2026-05-08 Christopher G. Pedraza Pohlenz , Hassan Jalil Hadi , Ali Hassan , Ali Shoker

Dead code introduces several challenges in software development, such as increased binary size and maintenance difficulties. It can also obscure logical errors and be exploited for obfuscation in malware. For LLM-based code-related tasks,…

Software Engineering · Computer Science 2025-06-16 Minyu Chen , Guoqiang Li , Ling-I Wu , Ruibang Liu

By encoding time series as a string of numerical digits, we can frame time series forecasting as next-token prediction in text. Developing this approach, we find that large language models (LLMs) such as GPT-3 and LLaMA-2 can surprisingly…

Machine Learning · Computer Science 2024-08-13 Nate Gruver , Marc Finzi , Shikai Qiu , Andrew Gordon Wilson

Recent advancements in Large Language Models (LLMs) have led to their widespread application in automated code generation. However, these models can still generate defective code that deviates from the specification. Previous research has…

Software Engineering · Computer Science 2025-03-21 QiHong Chen , Jiachen Yu , Jiawei Li , Jiecheng Deng , Justin Tian Jin Chen , Iftekhar Ahmed

Large language models (LLMs) have shown impressive in-context learning (ICL) ability in code generation. LLMs take a prompt consisting of requirement-code examples and a new requirement as input, and output new programs. Existing studies…

Software Engineering · Computer Science 2023-10-17 Jia Li , Ge Li , Chongyang Tao , Jia Li , Huangzhao Zhang , Fang Liu , Zhi Jin
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