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Background: Existing clinical prediction models often represent patient data using features that ignore the semantic relationships between clinical concepts. This study integrates domain-specific semantic information by mapping the SNOMED…

Machine Learning · Computer Science 2025-08-21 Luis H. John , Jan A. Kors , Jenna M. Reps , Peter R. Rijnbeek , Egill A. Fridgeirsson

The exponential growth of neuroscientific data necessitates platforms that facilitate data management and multidisciplinary collaboration. In this paper, we introduce Pennsieve - an open-source, cloud-based scientific data management…

Computers and Society · Computer Science 2024-09-24 Zack Goldblum , Zhongchuan Xu , Haoer Shi , Patryk Orzechowski , Jamaal Spence , Kathryn A Davis , Brian Litt , Nishant Sinha , Joost Wagenaar

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single…

Machine Learning · Computer Science 2025-05-13 Fergus Imrie , Stefan Denner , Lucas S. Brunschwig , Klaus Maier-Hein , Mihaela van der Schaar

Classifying breast cancer molecular subtypes is crucial for tailoring treatment strategies. While immunohistochemistry (IHC) and gene expression profiling are standard methods for molecular subtyping, IHC can be subjective, and gene…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Masoud Tafavvoghi , Anders Sildnes , Mehrdad Rakaee , Nikita Shvetsov , Lars Ailo Bongo , Lill-Tove Rasmussen Busund , Kajsa Møllersen

Background: The integration of multi-stain histopathology images through deep learning poses a significant challenge in digital histopathology. Current multi-modal approaches struggle with data heterogeneity and missing data. This study…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Valentin Koch , Sabine Bauer , Valerio Luppberger , Michael Joner , Heribert Schunkert , Julia A. Schnabel , Moritz von Scheidt , Carsten Marr

Accurate uncertainty estimation is a critical challenge in open-set recognition, where a probe biometric sample may belong to an unknown identity. It can be addressed through sample quality estimation via probabilistic embeddings. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Leonid Erlygin , Alexey Zaytsev

The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

Cancer is a leading cause of death worldwide, necessitating advancements in early detection and treatment technologies. In this paper, we present a novel and highly efficient melanoma detection framework that synergistically combines the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Peng Zhang , Divya Chaudhary

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

Accurate detection and classification of nuclei in histopathology images are critical for diagnostic and research applications. We present KongNet, a multi-headed deep learning architecture featuring a shared encoder and parallel,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaqi Lv , Esha Sadia Nasir , Kesi Xu , Mostafa Jahanifar , Brinder Singh Chohan , Behnaz Elhaminia , Shan E Ahmed Raza

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

KonfAI is a modular, extensible, and fully configurable deep learning framework specifically designed for medical imaging tasks. It enables users to define complete training, inference, and evaluation workflows through structured YAML…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Valentin Boussot , Jean-Louis Dillenseger

Breast cancer is one of the leading causes of cancer-related mortality in women, and early detection is essential for improving outcomes. Magnetic resonance imaging (MRI) is a highly sensitive tool for breast cancer detection, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Smriti Joshi , Lidia Garrucho , Richard Osuala , Oliver Diaz , Karim Lekadir

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

Methodology · Statistics 2022-02-11 Dongyan Yan , Subharup Guha

Transformer-based detectors have advanced small-object detection, but they often remain inefficient and vulnerable to background-induced query noise, which motivates deep decoders to refine low-quality queries. We present HELP…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Yangchen Zeng , Zhenyu Yu , Dongming Jiang , Wenbo Zhang , Yifan Hong , Zhanhua Hu , Jiao Luo , Kangning Cui

Deep learning methods have been widely used for Human Activity Recognition (HAR) using recorded signals from Iner-tial Measurement Units (IMUs) sensors that are installed on various parts of the human body. For this type of HAR, sev-eral…

Machine Learning · Computer Science 2025-02-10 Saeed Arabzadeh , Farshad Almasganj , Mohammad Mahdi Ahmadi

Mapping X-ray images, radiology reports, and other medical data as binary codes in the common space, which can assist clinicians to retrieve pathology-related data from heterogeneous modalities (i.e., hashing-based cross-modal medical data…

Machine Learning · Computer Science 2022-05-18 Yufeng Shi , Shuhuang Chen , Xinge You , Qinmu Peng , Weihua Ou , Yue Zhao

This study proposes a novel perspective on multimodal deep learning for biomedical signal classification, systematically analyzing how complementary feature domains impact model performance. While fusing multiple domains often presumes…

Machine Learning · Computer Science 2025-08-05 Timothy Oladunni , Alex Wong

Survival prediction is a crucial task in the medical field and is essential for optimizing treatment options and resource allocation. However, current methods often rely on limited data modalities, resulting in suboptimal performance. In…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Binyu Zhang , Zhu Meng , Junhao Dong , Fei Su , Zhicheng Zhao

Recent advances in clinical AI have enabled remarkable progress across many clinical domains. However, existing benchmarks and models are primarily limited to a small set of modalities and tasks, which hinders the development of large-scale…

Machine Learning · Computer Science 2025-03-21 Wei Dai , Peilin Chen , Malinda Lu , Daniel Li , Haowen Wei , Hejie Cui , Paul Pu Liang
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